Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Michel, DuPage"'
Autor:
Janneke GC Peeters, Stephanie Silveria, Merve Ozdemir, Grigorios Georgolopoulos, Michel DuPage
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss Suppl 1 (2023)
Externí odkaz:
https://doaj.org/article/a5464f4f031d4264985ee78d383c7f9d
Autor:
David Wang, Jason Quiros, Kelly Mahuron, Chien-Chun Pai, Valeria Ranzani, Arabella Young, Stephanie Silveria, Tory Harwin, Arbi Abnousian, Massimiliano Pagani, Michael D. Rosenblum, Frederic Van Gool, Lawrence Fong, Jeffrey A. Bluestone, Michel DuPage
Publikováno v:
Cell Reports, Vol 23, Iss 11, Pp 3262-3274 (2018)
Summary: Regulatory T cells (Tregs) are critical for maintaining immune homeostasis, but their presence in tumor tissues impairs anti-tumor immunity and portends poor prognoses in cancer patients. Here, we reveal a mechanism to selectively target and
Externí odkaz:
https://doaj.org/article/a503e440cd0b44659da60774374572e3
Autor:
Janneke G C, Peeters, Michel, DuPage
Publikováno v:
Nature cancer. 2(10)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::76cac461839c55ff0b8895df9a6ff2b8
https://pubmed.ncbi.nlm.nih.gov/35121884
https://pubmed.ncbi.nlm.nih.gov/35121884
Autor:
Mariela A. Moreno Ayala, Timothy F. Campbell, Chenyu Zhang, Noa Dahan, Alissa K. Danford, Varsha Prakash, Lawrence Feng, Theo Sher, Michel DuPage
Publikováno v:
SSRN Electronic Journal.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::12877956e5662a08edbabdb78e4bd107
https://doi.org/10.2139/ssrn.4170185
https://doi.org/10.2139/ssrn.4170185
Autor:
Michael C. Zaiken, Ryan Flynn, Katelyn G. Paz, Stephanie Y. Rhee, Sujeong Jin, Fathima A. Mohamed, Asim Saha, Govindarajan Thangavelu, Paul M. C. Park, Matthew L. Hemming, Peter T. Sage, Arlene H. Sharpe, Michel DuPage, Jeffrey A. Bluestone, Angela Panoskaltsis-Mortari, Corey S. Cutler, John Koreth, Joseph H. Antin, Robert J. Soiffer, Jerome Ritz, Leo Luznik, Ivan Maillard, Geoffrey R. Hill, Kelli P. A. MacDonald, David H. Munn, Jonathan S. Serody, William J. Murphy, Leslie S. Kean, Yi Zhang, James E. Bradner, Jun Qi, Bruce R. Blazar
Publikováno v:
Blood. 139(19)
Despite advances in the field, chronic graft-versus-host-disease (cGVHD) remains a leading cause of morbidity and mortality following allogenic hematopoietic stem cell transplant. Because treatment options remain limited, we tested efficacy of antica
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8789c02293084d644b919d40fc5faec8
https://pubmed.ncbi.nlm.nih.gov/35552645
https://pubmed.ncbi.nlm.nih.gov/35552645
Autor:
Maxim N. Artyomov, Daniele Runci, Ilya Kizhvatov, Ruan F.V. Medrano, Kai W. Wucherpfennig, Danielle M. Lussier, Wei Meng, Cheryl F. Lichti, Kathleen C. F. Sheehan, Jeffrey P. Ward, Tyler Jacks, Alexander Chen, Adrienne M. Luoma, J. Michael White, Elise Alspach, Alexander P. Miceli, Matthew M. Gubin, Emil R. Unanue, Robert D. Schreiber, Michel DuPage, Ekaterina Esaulova, Anthony N. Vomund, Cora D. Arthur
Publikováno v:
PMC
Nature
Nature
The ability of the immune system to eliminate and shape the immunogenicity of tumours defines the process of cancer immunoediting1. Immunotherapies such as those that target immune checkpoint molecules can be used to augment immune-mediated eliminati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d98cb1bdaed9042b4a16e69dd9e0c149
https://doi.org/10.1038/s41586-019-1671-8
https://doi.org/10.1038/s41586-019-1671-8
Autor:
Banu Eskiocak, Celeste Dang, Da-Yae Lee, Ryan Kohn, Tyler Jacks, Michel DuPage, Leah Marie Schmidt, Nikhil S. Joshi
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Significance T cell-targeted therapies are effective against lung cancer only in a fraction of patients, highlighting a need for complimentary approaches. In genetically engineered lung cancer in mice, stimulation of natural killer cells in establish
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a76a0e6e3cedd3eccaea5cbd5579e07
https://doi.org/10.1073/pnas.1904253116
https://doi.org/10.1073/pnas.1904253116
Autor:
Michel DuPage, Janneke G. C. Peeters
Publikováno v:
Nature Cancer. 2:996-997
Shedding light on epigenetic mechanisms controlling anti-tumor immune responses, a new study shows that the tumor-intrinsic ring finger protein 2 (RNF2), the catalytic subunit of Polycomb repressor complex 1 (PRC1), acts as a negative regulator of a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ccbeef4efec2b987f946e9460d3045c2
https://doi.org/10.1038/s43018-021-00270-0
https://doi.org/10.1038/s43018-021-00270-0
Autor:
Michel DuPage
Publikováno v:
Cancer Research. 81:IA012-IA012
The treatment of cancer has been revolutionized by the development of immune-based therapies designed to boost the number and function of cytotoxic T cells that kill tumor cells. However, it is already apparent that this strategy alone will not benef
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0af35622c80b7a403ae6f5f4a71a10fb
https://doi.org/10.1158/1538-7445.tme21-ia012
https://doi.org/10.1158/1538-7445.tme21-ia012
Autor:
Jeffrey A. Bluestone, Michel DuPage
Publikováno v:
Dupage, M; & Bluestone, JA. (2016). Harnessing the plasticity of CD4+ T cells to treat immune-mediated disease. Nature Reviews Immunology, 16(3), 149-163. doi: 10.1038/nri.2015.18. UC San Francisco: Retrieved from: http://www.escholarship.org/uc/item/86r4b1pf
Nature reviews. Immunology, vol 16, iss 3
Nature reviews. Immunology, vol 16, iss 3
© 2016 Macmillan Publishers Limited. CD4 + T cells differentiate and acquire distinct functions to combat specific pathogens but can also adapt their functions in response to changing circumstances. Although this phenotypic plasticity can be potenti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4946ea5e70ed65bafeb5e8435f1ae913
https://doi.org/10.1038/nri.2015.18
https://doi.org/10.1038/nri.2015.18