Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Michel, Cailleret"'
Autor:
Elie Frank, Michel Cailleret, Constantin Nelep, Pascal Fragner, Jérome Polentes, Elise Herardot, Lina El Kassar, Karine Giraud-Triboult, Christelle Monville, Karim Ben M’Barek
Publikováno v:
Stem Cell Research & Therapy, Vol 14, Iss 1, Pp 1-14 (2023)
Abstract Background CRISPR/Cas9 editing systems are currently used to generate mutations in a particular gene to mimic a genetic disorder in vitro. Such “disease in a dish” models based on human pluripotent stem cells (hPSCs) offer the opportunit
Externí odkaz:
https://doaj.org/article/a0978364e13741ee98c9f4e6a67499fa
Autor:
Jérôme Polentes, Hélène Polvèche, Cécile Martinat, Axel Sciauvaud, Maria-Gabriela Boza-Moran, Laetitia Aubry, Marc Peschanski, Margot Jarrige, Sandra Pourtoy-Brasselet, Michel Cailleret, Eric Chevet
Publikováno v:
American Journal of Human Genetics
American Journal of Human Genetics, 2021, 108 (11), pp.2171-2185. ⟨10.1016/j.ajhg.2021.10.001⟩
American Journal of Human Genetics, Elsevier (Cell Press), 2021, 108 (11), pp.2171-2185. ⟨10.1016/j.ajhg.2021.10.001⟩
Am J Hum Genet
American Journal of Human Genetics, 2021, 108 (11), pp.2171-2185. ⟨10.1016/j.ajhg.2021.10.001⟩
American Journal of Human Genetics, Elsevier (Cell Press), 2021, 108 (11), pp.2171-2185. ⟨10.1016/j.ajhg.2021.10.001⟩
Am J Hum Genet
International audience; Recent studies indicate that neurodegenerative processes that appear during childhood and adolescence in individuals with Wolfram syndrome (WS) occur in addition to early brain development alteration, which is clinically silen
Autor:
Céline Leteur, Margot Jarrige, Jérôme Polentes, Hélène Polvèche, Denis Furling, Cécile Martinat, Christian Pinset, Alexandre Carteron, Julie Tahraoui-Bories, Jean-Paul Concordet, Antoine Mérien, Michel Cailleret, Jean-Baptiste Dupont
Publikováno v:
Human Molecular Genetics
Human Molecular Genetics, 2022, 31 (1), pp.41-56. ⟨10.1093/hmg/ddab218⟩
Human Molecular Genetics, 2022, 31 (1), pp.41-56. ⟨10.1093/hmg/ddab218⟩
Alternative splicing has emerged as a fundamental mechanism for the spatiotemporal control of development. A better understanding of how this mechanism is regulated has the potential not only to elucidate fundamental biological principles, but also t
Autor:
Jérôme Polentes, Pavla Jendelova, Michel Cailleret, Holger Braun, Nataliya Romanyuk, Philippe Tropel, Marion Brenot, Valerie Itier, Christine Seminatore, Kathrin Baldauf, Karolina Turnovcova, Daniel Jirak, Marius Teletin, Julien Côme, Johana Tournois, Klaus Reymann, Eva Sykova, Stéphane Viville, Brigitte Onteniente
Publikováno v:
Cell Transplantation, Vol 21 (2012)
Human induced pluripotent stem cells (hiPSCs) are a most appealing source for cell replacement therapy in acute brain lesions. We evaluated the potential of hiPSC therapy in stroke by transplanting hiPSC-derived neural progenitor cells (NPCs) into th
Externí odkaz:
https://doaj.org/article/f3cf046e2ed744fcb08b607d843f1e68
Autor:
Laetitia, Barrault, Jacqueline, Gide, Tingting, Qing, Lea, Lesueur, Jorg, Tost, Jerome Alexandre, Denis, Michel, Cailleret, Laetitia, Aubry, Marc, Peschanski, Cécile, Martinat, Sandrine, Baghdoyan
Publikováno v:
Cells
Substantial variations in differentiation properties have been reported among human pluripotent cell lines (hPSC), which could affect their utility and clinical safety. We characterized the variable osteogenic capacity observed between different huma
Autor:
Margot Jarrige, Julie Bigarreau, Gabriel Vachey, Morgane Louessard, Nicole Déglon, Anselme L. Perrier, Michel Cailleret
Publikováno v:
Pathogenic mechanisms.
In Huntington disease (HD), the most affected cells are the GABA-releasing medium spiny neurons (MSN) of the striatum, the subcortical brain structure that controls body movement. DARPP32 (dopamine- and 3’,5’-cyclic adenosine monophosphate-regula
Autor:
Camille Nicoleau, Michel Cailleret, Marc Lechuga, Benjamin Brinon, Martine Guillermier, Emmanuel Brouillet, Caroline Bonnefond, Laetitia Francelle, Maxime Feyeux, Pedro Viegas, Gwenaëlle Auregan, Cécile Martinat, Marc Peschanski, Elena Cattaneo, Anselme L. Perrier, Jérémie Charbord, Pauline Poydenot, Fabrice Casagrande
Publikováno v:
STEM CELLS
STEM CELLS; Vol 31
STEM CELLS; Vol 31
Decreased expression of neuronal genes such as brain-derived neurotrophic factor (BDNF) is associated with several neurological disorders. One molecular mechanism associated with Huntington disease (HD) is a discrete increase in the nuclear activity
Autor:
Yacine Laâbi, Johana Tournois, Julien Côme, Pascal Fragner, Michel Cailleret, Philippe Tropel, Christine Varela, Marc Peschanski, Céline Moutou, Stéphane Viville
Publikováno v:
In Vitro Cellular & Developmental Biology - Animal. 46:376-385
Pre-implantation genetic diagnosis allows the characterisation of embryos that carry a gene responsible for a severe monogenic disease and to transfer to the mother’s uterus only the unaffected one(s). The genetically affected embryos can be used t
Autor:
Marc Peschanski, Laetitia Aubry, Johana Tournois, Julien Côme, Anselme L. Perrier, Xavier Nissan, Michel Cailleret, Mathilde Girard
Publikováno v:
Tissue Engineering Part C: Methods. 14:289-298
In parallel to the active search for therapeutic and industrial applications of human embryonic stem cells (hESCs), designing automated means of producing those cells is a timely goal. Slow-turning lateral vessels (STLVs) with low shear stress have s
Autor:
Martha Cecilia Rosales-Hernández, Vandana Joshi, Michel Cailleret, Martha Edith Macías Pérez, Cyril Bauvais, Flavio Toma, Andrea Burgo, Imane Hamdi, Guillaume Bollot, Patrick A. Curmi, Marie-Jeanne Clément, Daoudi Chabane-Sari, Meryem Sari-Hassoun
Publikováno v:
Biochemical Pharmacology
Biochemical Pharmacology, Elsevier, 2016, 102, pp.45-63. ⟨10.1016/j.bcp.2015.12.013⟩
Biochemical Pharmacology, 2016, 102, pp.45-63. ⟨10.1016/j.bcp.2015.12.013⟩
Biochemical Pharmacology, Elsevier, 2016, 102, pp.45-63. ⟨10.1016/j.bcp.2015.12.013⟩
Biochemical Pharmacology, 2016, 102, pp.45-63. ⟨10.1016/j.bcp.2015.12.013⟩
International audience; Cucurbitacins are cytotoxic triterpenoid sterols isolated from plants. One of their earliest cellular effect is the aggregation of actin associated with blockage of cell migration and division that eventually lead to apoptosis