Zobrazeno 1 - 10 of 300 pro vyhledávání: '"Michel, Bolla"'
1
Akademický článek
RND Efflux Pump Induction: A Crucial Network Unveiling Adaptive Antibiotic Resistance Mechanisms of Gram-Negative Bacteria
Autor: Marine Novelli, Jean-Michel Bolla
Publikováno v: Antibiotics, Vol 13, Iss 6, p 501 (2024)
The rise of multi-drug-resistant (MDR) pathogenic bacteria presents a grave challenge to global public health, with antimicrobial resistance ranking as the third leading cause of mortality worldwide. Understanding the mechanisms underlying antibiotic
Externí odkaz: https://doaj.org/article/2bea3156383e46a5b8d5e5ffbfaa82bc
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2
Akademický článek
Design and Synthesis of Novel Amino and Acetamidoaurones with Antimicrobial Activities
Autor: Attilio Di Maio, Hamza Olleik, Elise Courvoisier-Dezord, Sophie Guillier, Fabienne Neulat-Ripoll, Romain Haudecoeur, Jean-Michel Bolla, Magali Casanova, Jean-François Cavalier, Stéphane Canaan, Valérie Pique, Yolande Charmasson, Elias Baydoun, Akram Hijazi, Josette Perrier, Marc Maresca, Maxime Robin
Publikováno v: Antibiotics, Vol 13, Iss 4, p 300 (2024)
The development of new and effective antimicrobial compounds is urgent due to the emergence of resistant bacteria. Natural plant flavonoids are known to be effective molecules, but their activity and selectivity have to be increased. Based on previou
Externí odkaz: https://doaj.org/article/5d8370f86fa64562addc888a21f1289e
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3
Akademický článek
The membrane-active polyaminoisoprenyl compound NV716 re-sensitizes Pseudomonas aeruginosa to antibiotics and reduces bacterial virulence
Autor: Gang Wang, Jean-Michel Brunel, Matthias Preusse, Negar Mozaheb, Sven D. Willger, Gerald Larrouy-Maumus, Pieter Baatsen, Susanne Häussler, Jean-Michel Bolla, Françoise Van Bambeke
Publikováno v: Communications Biology, Vol 5, Iss 1, Pp 1-17 (2022)
The polyaminoisoprenyl compound NV716 re-sensitizes Pseudomonas aeruginosa to antibiotics through permeabilizing the outer membrane and increases the activity of antibiotics on biofilms.
Externí odkaz: https://doaj.org/article/33f1fe5183d344fa843566795f556d80
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4
Akademický článek
Tolerance engineering in Deinococcus geothermalis by heterologous efflux pumps
Autor: Erika Boulant, Emmanuelle Cambon, Julia Vergalli, Rémi Bernard, Fabienne Neulat-Ripoll, Flora Nolent, Olivier Gorgé, Maria Girleanu, Anne-Laure Favier, Jean-Paul Leonetti, Jean Michel Bolla
Publikováno v: Scientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)
Abstract Producing industrially significant compounds with more environmentally friendly represents a challenging task. The large-scale production of an exogenous molecule in a host microfactory can quickly cause toxic effects, forcing the cell to in
Externí odkaz: https://doaj.org/article/58071f4de37f4a468739d178ae7eda85
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5
Akademický článek
The role of radiotherapy in localised and locally advanced prostate cancer
Autor: Michel Bolla, Ann Henry, Malcom Mason, Thomas Wiegel
Publikováno v: Asian Journal of Urology, Vol 6, Iss 2, Pp 153-161 (2019)
For a patient suffering from non-metastatic prostate cancer, the individualized recommendation of radiotherapy has to be the fruit of a multidisciplinary approach in the context of a Tumor Board, to be explained carefully to the patient to obtain his
Externí odkaz: https://doaj.org/article/2dde49718f9741099b0ba5cf78fde03d
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7
Akademický článek
Peptide translocation across MOMP, the major outer membrane channel from Campylobacter jejuni
Autor: Naresh Niranjan Dhanasekar, Soumeya Aliouane, Mathias Winterhalter, Jean-Marie Pagès, Jean-Michel Bolla
Publikováno v: Biochemistry and Biophysics Reports, Vol 11, Iss C, Pp 79-83 (2017)
Here we report on translocation of short poly-arginines across the MOMP porin, the major outer membrane protein in the cell wall of Campylobacter jejuni. MOMP was purified to homogeneity from a pathogenic strain of C. jejuni. Its reconstitution in li
Externí odkaz: https://doaj.org/article/fe7136f606a44a22926d059f34690804
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10
Akademický článek
Polyamino-Isoprenyl Derivatives as Antibiotic Adjuvants and Motility Inhibitors for Bordetella bronchiseptica Porcine Pulmonary Infection Treatment
Autor: Diane Borselli, Jean Michel Brunel, Olivier Gorgé, Jean Michel Bolla
Publikováno v: Frontiers in Microbiology, Vol 10 (2019)
The spreading of multidrug-resistant bacteria and the lack of novel antibiotic molecules leave clinicians and veterinarians with very limited options to treat bacterial infections, especially those caused by Gram-negative pathogens. To reduce the sel
Externí odkaz: https://doaj.org/article/d06f590808f446d191d7fa882c68331a
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