Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Micheal Leser"'
Publikováno v:
BBA Advances, Vol 3, Iss , Pp 100079- (2023)
Accumulation of advanced glycation end products (AGEs), particularly in long-lived extracellular matrix proteins, has been implicated in pathogenesis of diabetic complications and in aging. Knowledge about specific locations of AGEs and their precurs
Externí odkaz:
https://doaj.org/article/a1a76c6c18c242e9b7106fb87f251d94
Autor:
Leandro Cerchietti, Ari Melnick, John P. Leonard, Giorgio Inghirami, Katherine L. Borden, Randy D. Gascoyne, Lucy A. Godley, Fabrizio Tabbo, Amy Chadburn, Rita Shaknovich, Micheal Leser, Sarah Wyman, David W. Scott, Biljana Culjkovic, Aparna Vasanthakumar, Samprit Banerjee, Matthias Kormaksson, Peter Martin, Wayne Tam, Rebecca L. Elstrom, ShaoNing Yang, Thomas Clozel
Figure S5 - PDF file 224K, Toxicity studies in mice
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::12229b5cf6bc86e4efd6d0e0b8d98300
https://doi.org/10.1158/2159-8290.22530860
https://doi.org/10.1158/2159-8290.22530860
Autor:
Leandro Cerchietti, Ari Melnick, John P. Leonard, Giorgio Inghirami, Katherine L. Borden, Randy D. Gascoyne, Lucy A. Godley, Fabrizio Tabbo, Amy Chadburn, Rita Shaknovich, Micheal Leser, Sarah Wyman, David W. Scott, Biljana Culjkovic, Aparna Vasanthakumar, Samprit Banerjee, Matthias Kormaksson, Peter Martin, Wayne Tam, Rebecca L. Elstrom, ShaoNing Yang, Thomas Clozel
Figures S7, S8 and S9 - PDF file 206K, SMAD1 expression in patients and functional experiments
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ca549b750f9d6f63af947e11464c660
https://doi.org/10.1158/2159-8290.22530851
https://doi.org/10.1158/2159-8290.22530851
Autor:
Leandro Cerchietti, Ari Melnick, John P. Leonard, Giorgio Inghirami, Katherine L. Borden, Randy D. Gascoyne, Lucy A. Godley, Fabrizio Tabbo, Amy Chadburn, Rita Shaknovich, Micheal Leser, Sarah Wyman, David W. Scott, Biljana Culjkovic, Aparna Vasanthakumar, Samprit Banerjee, Matthias Kormaksson, Peter Martin, Wayne Tam, Rebecca L. Elstrom, ShaoNing Yang, Thomas Clozel
Supplementary Methods - PDF file 100K, Reagents, gene expression profiling, RT-PCR, mice studies, clinical trial, patient samples, ex vivo treatments, immunohistochemistry and statistical analysis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2326ec3a1d30f923d31bcbe2ba3c981c
https://doi.org/10.1158/2159-8290.22530845.v1
https://doi.org/10.1158/2159-8290.22530845.v1
Table S2 from Mechanism-Based Epigenetic Chemosensitization Therapy of Diffuse Large B-Cell Lymphoma
Autor:
Leandro Cerchietti, Ari Melnick, John P. Leonard, Giorgio Inghirami, Katherine L. Borden, Randy D. Gascoyne, Lucy A. Godley, Fabrizio Tabbo, Amy Chadburn, Rita Shaknovich, Micheal Leser, Sarah Wyman, David W. Scott, Biljana Culjkovic, Aparna Vasanthakumar, Samprit Banerjee, Matthias Kormaksson, Peter Martin, Wayne Tam, Rebecca L. Elstrom, ShaoNing Yang, Thomas Clozel
Table S2 - PDF file 62K, Genes hypermethylated and repressed in doxorubicin resistant cell lines
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::62d7982bda9ee4ee2866f7c05b2d8894
https://doi.org/10.1158/2159-8290.22530839.v1
https://doi.org/10.1158/2159-8290.22530839.v1
Autor:
Kavi P. M. Mehta, Vaughn Thada, Runxiang Zhao, Archana Krishnamoorthy, Micheal Leser, Kristie Lindsey Rose, David Cortez
Publikováno v:
Science Advances. 8
Replication-coupled DNA repair and damage tolerance mechanisms overcome replication stress challenges and complete DNA synthesis. These pathways include fork reversal, translesion synthesis, and repriming by specialized polymerases such as PRIMPOL. H
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0bd56af36d57ec5e3fb1b2d550326499
https://doi.org/10.1126/sciadv.abm0314
https://doi.org/10.1126/sciadv.abm0314
Autor:
Matt Law, Micheal Leser, Beatrix Ueberheide, Michael Brenowitz, Jonathan Pegan, Mohammed El Makkaoui, Michelle Khine, Jessica R. Chapman
Publikováno v:
Protein & Peptide Letters. 26:61-69
Background:For almost four decades, hydroxyl radical chemically generated by Fenton chemistry has been a mainstay for the oxidative ‘footprinting’ of macromolecules.Objective:In this article, we start by reviewing the application of chemical gene
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9780868e65cc95bb6d2b91a1fff51d46
https://doi.org/10.2174/0929866526666181212164812
https://doi.org/10.2174/0929866526666181212164812
Autor:
Michael Brenowitz, Joerg C. Schlatterer, Jonathan Pegan, Mohammed El Makkaoui, Micheal Leser, Michelle Khine, Matt Law
Publikováno v:
Lab on a chip, vol 15, iss 7
Lab Chip
Lab Chip
The structure of macromolecules and their complexes dictate their biological function. In “footprinting”, the solvent accessibility of the residues that constitute proteins, DNA and RNA can be determined from their reactivity to an exogenous reag
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e990a427d717a6acbdb30d3bc60012ac
https://doi.org/10.1039/c4lc01288g
https://doi.org/10.1039/c4lc01288g
Autor:
Rita Shaknovich, Biljana Culjkovic, Rebecca Elstrom, Ari Melnick, Amy Chadburn, David Scott, John P. Leonard, Sarah Wyman, Wayne Tam, Peter Martin, Micheal Leser, Giorgio Inghirami, Randy D. Gascoyne, Matthias Kormaksson, Aparna Vasanthakumar, Shao Ning Yang, Fabrizio Tabbò, Thomas Clozel, Katherine L. B. Borden, Samprit Banerjee, Lucy A. Godley, Leandro Cerchietti
Although aberrant DNA methylation patterning is a hallmark of cancer, the relevance of targeting DNA methyltransferases (DNMT) remains unclear for most tumors. In diffuse large B-cell lymphoma (DLBCL) we observed that chemoresistance is associated wi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b6ed197e0c4ff3e3749f76f4655847da
https://europepmc.org/articles/PMC3770813/
https://europepmc.org/articles/PMC3770813/