Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Micheal G. Darnowski"'
Autor:
André R. Paquette, Sterling R. Payne, Geoffrey A. McKay, Jordan T. Brazeau-Henrie, Micheal G. Darnowski, Anitha Kammili, Federico Bernal, Thien-Fah Mah, Samantha Gruenheid, Dao Nguyen, Christopher N. Boddy
Publikováno v:
RSC Medicinal Chemistry. 13:445-455
Optimized RpoN-based stapled peptides selectively bind promoter DNA sequence and inhibit virulence of Pseudomonas aeruginosa in an in vivo model.
Autor:
André R, Paquette, Sterling R, Payne, Geoffrey A, McKay, Jordan T, Brazeau-Henrie, Micheal G, Darnowski, Anitha, Kammili, Federico, Bernal, Thien-Fah, Mah, Samantha, Gruenheid, Dao, Nguyen, Christopher N, Boddy
Publikováno v:
RSC Med Chem
Stapled peptides have the ability to mimic α-helices involved in protein binding and have proved to be effective pharmacological agents for disrupting protein–protein interactions. DNA-binding proteins such as transcription factors bind their cogn