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pro vyhledávání: '"Micheal D. Schaber"'
Autor:
Rands E, Samuel L. Graham, George D. Hartman, Nancy E. Kohl, Micheal D. Schaber, Robert P. Gomez, Oliff Allen I, Daksha Shah, Neville J. Anthony, Scott D. Mosser, Kelly Hamilton, Timothy J. O'Neil, Kenneth S. Koblan, Jackson B. Gibbs
Publikováno v:
Journal of medicinal chemistry. 42(17)
Inhibitors of farnesyl protein transferase (FPTase) based upon a pseudotripeptide template are described that comprise an imidazole group substituted with a hydrophobic substituent. (1, 5)-Disubstitution of the imidazole group is shown to be the opti