Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Michalis Hadjithomas"'
Autor:
Samuel P. Forry, Stephanie L. Servetas, Jason G. Kralj, Keng Soh, Michalis Hadjithomas, Raul Cano, Martha Carlin, Maria G. de Amorim, Benjamin Auch, Matthew G. Bakker, Thais F. Bartelli, Juan P. Bustamante, Ignacio Cassol, Mauricio Chalita, Emmanuel Dias-Neto, Aaron Del Duca, Daryl M. Gohl, Jekaterina Kazantseva, Muyideen T. Haruna, Peter Menzel, Bruno S. Moda, Lorieza Neuberger-Castillo, Diana N. Nunes, Isha R. Patel, Rodrigo D. Peralta, Adrien Saliou, Rolf Schwarzer, Samantha Sevilla, Isabella K. T. M. Takenaka, Jeremy R. Wang, Rob Knight, Dirk Gevers, Scott A. Jackson
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-14 (2024)
Abstract Several studies have documented the significant impact of methodological choices in microbiome analyses. The myriad of methodological options available complicate the replication of results and generally limit the comparability of findings b
Externí odkaz:
https://doaj.org/article/9326cd72a787444696c754805552b79a
Autor:
Alexander M Kloosterman, Peter Cimermancic, Somayah S Elsayed, Chao Du, Michalis Hadjithomas, Mohamed S Donia, Michael A Fischbach, Gilles P van Wezel, Marnix H Medema
Publikováno v:
PLoS Biology, Vol 18, Iss 12, p e3001026 (2020)
Microbial natural products constitute a wide variety of chemical compounds, many which can have antibiotic, antiviral, or anticancer properties that make them interesting for clinical purposes. Natural product classes include polyketides (PKs), nonri
Externí odkaz:
https://doaj.org/article/37a2f5ceef8e46f8a72e0714fee61104
Autor:
Jie Xiong, Wentao Yang, Kai Chen, Chuanqi Jiang, Yang Ma, Xiaocui Chai, Guanxiong Yan, Guangying Wang, Dongxia Yuan, Yifan Liu, Shelby L Bidwell, Nikhat Zafar, Michalis Hadjithomas, Vivek Krishnakumar, Robert S Coyne, Eduardo Orias, Wei Miao
Publikováno v:
PLoS Biology, Vol 17, Iss 6, p e3000294 (2019)
A morphospecies is defined as a taxonomic species based wholly on morphology, but often morphospecies consist of clusters of cryptic species that can be identified genetically or molecularly. The nature of the evolutionary novelty that accompanies sp
Externí odkaz:
https://doaj.org/article/f400c8dce213444cb2a01bfe2025ac91
Autor:
Hernan Lorenzi, Asis Khan, Michael S. Behnke, Sivaranjani Namasivayam, Lakshmipuram S. Swapna, Michalis Hadjithomas, Svetlana Karamycheva, Deborah Pinney, Brian P. Brunk, James W. Ajioka, Daniel Ajzenberg, John C. Boothroyd, Jon P. Boyle, Marie L. Dardé, Maria A. Diaz-Miranda, Jitender P. Dubey, Heather M. Fritz, Solange M. Gennari, Brian D. Gregory, Kami Kim, Jeroen P. J. Saeij, Chunlei Su, Michael W. White, Xing-Quan Zhu, Daniel K. Howe, Benjamin M. Rosenthal, Michael E. Grigg, John Parkinson, Liang Liu, Jessica C. Kissinger, David S. Roos, L. David Sibley
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-13 (2016)
Toxoplasma gondii is a parasite that causes zoonotic infections in humans. Here, the authors identify tandem amplification and diversification of secretory pathogenesis determinants in the T. gondiigenome and show that clade-specific inheritance of c
Externí odkaz:
https://doaj.org/article/d6f0f5ce233e43bc8b47026b7307e2e5
Autor:
Eileen P Hamilton, Aurélie Kapusta, Piroska E Huvos, Shelby L Bidwell, Nikhat Zafar, Haibao Tang, Michalis Hadjithomas, Vivek Krishnakumar, Jonathan H Badger, Elisabet V Caler, Carsten Russ, Qiandong Zeng, Lin Fan, Joshua Z Levin, Terrance Shea, Sarah K Young, Ryan Hegarty, Riza Daza, Sharvari Gujja, Jennifer R Wortman, Bruce W Birren, Chad Nusbaum, Jainy Thomas, Clayton M Carey, Ellen J Pritham, Cédric Feschotte, Tomoko Noto, Kazufumi Mochizuki, Romeo Papazyan, Sean D Taverna, Paul H Dear, Donna M Cassidy-Hanley, Jie Xiong, Wei Miao, Eduardo Orias, Robert S Coyne
Publikováno v:
eLife, Vol 5 (2016)
The germline genome of the binucleated ciliate Tetrahymena thermophila undergoes programmed chromosome breakage and massive DNA elimination to generate the somatic genome. Here, we present a complete sequence assembly of the germline genome and analy
Externí odkaz:
https://doaj.org/article/5b8a3b25eb90453aad49d3598e13d79e
Autor:
Marcella D Cervantes, Eileen P Hamilton, Jie Xiong, Michael J Lawson, Dongxia Yuan, Michalis Hadjithomas, Wei Miao, Eduardo Orias
Publikováno v:
PLoS Biology, Vol 13, Iss 10, p e1002284 (2015)
Externí odkaz:
https://doaj.org/article/61022532a48740809c9332860d25de9e
Autor:
Michalis Hadjithomas, I-Min Amy Chen, Ken Chu, Anna Ratner, Krishna Palaniappan, Ernest Szeto, Jinghua Huang, T. B. K. Reddy, Peter Cimermančič, Michael A. Fischbach, Natalia N. Ivanova, Victor M. Markowitz, Nikos C. Kyrpides, Amrita Pati
Publikováno v:
mBio, Vol 6, Iss 4 (2015)
ABSTRACT In the discovery of secondary metabolites, analysis of sequence data is a promising exploration path that remains largely underutilized due to the lack of computational platforms that enable such a systematic approach on a large scale. In th
Externí odkaz:
https://doaj.org/article/af361eacc5134f4c8014f632c2e40e70
Autor:
Marcella D Cervantes, Eileen P Hamilton, Jie Xiong, Michael J Lawson, Dongxia Yuan, Michalis Hadjithomas, Wei Miao, Eduardo Orias
Publikováno v:
PLoS Biology, Vol 11, Iss 3, p e1001518 (2013)
The unicellular eukaryote Tetrahymena thermophila has seven mating types. Cells can mate only when they recognize cells of a different mating type as non-self. As a ciliate, Tetrahymena separates its germline and soma into two nuclei. During growth t
Externí odkaz:
https://doaj.org/article/19eaf37fd94b4fef9eed7022bd221623
Autor:
Samuel P. Forry, Stephanie L. Servetas, Jason G. Kralj, Keng Soh, Michalis Hadjithomas, Raul Cano, Martha Carlin, Maria G de Amorim, Benjamin Auch, Matthew G Bakker, Thais F Bartelli, Juan P. Bustamante, Ignacio Cassol, Mauricio Chalita, Emmanuel Dias-Neto, Aaron Del Duca, Daryl M. Gohl, Jekaterina Kazantseva, Muyideen T. Haruna, Peter Menzel, Bruno S Moda, Lorieza Neuberger-Castillo, Diana N Nunes, Isha R. Patel, Rodrigo D. Peralta, Adrien Saliou, Rolf Schwarzer, Samantha Sevilla, Isabella K T M Takenaka, Jeremy R. Wang, Rob Knight, Dirk Gevers, Scott A. Jackson
BackgroundSeveral studies have documented the significant impact of methodological choices in microbiome analyses. The myriad of methodological options available complicate the replication of results and generally limit the comparability of findings
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::70332dd7ea0edd61b896d06cc8a91aa8
https://doi.org/10.1101/2023.04.28.538741
https://doi.org/10.1101/2023.04.28.538741
Autor:
Jing Ke, Zhiying Zhao, Cameron R. Coates, Michalis Hadjithomas, Andrea Kuftin, Katherine Louie, David Weller, Linda Thomashow, Nigel J. Mouncey, Trent R. Northen, Yasuo Yoshikuni
Publikováno v:
Metabolic engineering. 69
Phenazines (Phzs), a family of chemicals with a phenazine backbone, are secondary metabolites with diverse properties such as antibacterial, anti-fungal, or anticancer activity. The core derivatives of phenazine, phenazine-1-carboxylic acid (PCA) and