muLTi-Arm Therapeutic study in pre-ICu patients admitted with Covid-19-Experimental drugs and mechanisms (TACTIC-E): A structured summary of a study protocol for a randomized controlled trial

Autor: Ing Ni Lu, Spoorthy Kulkarni, Marie Fisk, Michalis Kostapanos, Edward Banham-Hall, Sonakshi Kadyan, Simon Bond, Sam Norton, Andrew Cope, James Galloway, Frances Hall, David Jayne, Ian B. Wilkinson, Joseph Cheriyan

Publikováno v: Trials, Vol 21, Iss 1, Pp 1-3 (2020)

Abstract Objectives To determine if a specific intervention reduces the composite of progression of patients with COVID-19-related disease to organ failure or death as measured by time to incidence of any one of the following: death, invasive mechani

Externí odkaz: https://doaj.org/article/687f408b59e14999b1fbb41441801e5d

Advanced imaging for quantification of abnormalities in the salivary glands of patients with primary Sjögren’s syndrome

Autor: Nicolas Wisniacki, Azeem Saleem, Paul Galette, Coziana Ciurtin, Ruth M. Tarzi, Teresa Fuller, Kathleen Port, Robert L. Janiczek, Davide Lucchesi, Calum Gray, Marius de Groot, Pilar Jimenez-Royo, Anwar R. Tappuni, Michele Bombardieri, Michalis Kostapanos, Mats Bergström, Elena Pontarini, Natasha Jordan, Nirav Ratia, André van Maurik, Neel Patel, Lucy E Kershaw, Graham E. Searle

Publikováno v: Jimenez-royo, P, Bombardieri, M, Ciurtin, C, Kostapanos, M, Tappuni, A R, Jordan, N, Saleem, A, Fuller, T, Port, K, Pontarini, E, Lucchesi, D, Janiczek, R L, Galette, P, Searle, G E, Patel, N, Kershaw, L, Gray, C, Ratia, N, van Maurik, A, de Groot, M, Wisniacki, N, Bergstrom, M & Tarzi, R 2021, ' Advanced imaging for quantification of abnormalities in the salivary glands of patients with primary Sjögren's Syndrome ', Rheumatology, vol. 60, no. 5, pp. 2396–2408 . https://doi.org/10.1093/rheumatology/keaa624
Rheumatology (Oxford, England)

Objectives To assess non-invasive imaging for detection and quantification of gland structure, inflammation and function in patients with primary Sjogren's syndrome (pSS) using PET-CT with 11C-Methionine (11C-MET; radiolabelled amino acid), and 18F-f

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cb3aca584b8b2814615a95056b6a1eea
https://doi.org/10.1093/rheumatology/keaa624

muLTi-Arm Therapeutic study in pre-ICu patients admitted with Covid-19-Experimental drugs and mechanisms (TACTIC-E): A structured summary of a study protocol for a randomized controlled trial

Autor: David Jayne, James Galloway, Sonakshi Kadyan, Michalis Kostapanos, Edward Banham-Hall, Frances Hall, Simon Bond, Joseph Cheriyan, Andrew P. Cope, Ian B. Wilkinson, Spoorthy Kulkarni, Ing Ni Lu, Marie Fisk, Sam Norton

Publikováno v: Trials, Vol 21, Iss 1, Pp 1-3 (2020)
Trials

Objectives To determine if a specific intervention reduces the composite of progression of patients with COVID-19-related disease to organ failure or death as measured by time to incidence of any one of the following: death, invasive mechanical venti

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6da1616b6e217bb8dc2a101c04b19523
http://link.springer.com/article/10.1186/s13063-020-04618-2

Baricitinib set to join the Covid-19 therapeutic arsenal?

Autor: Andrew P. Cope, Ian B. Wilkinson, Joseph Cheriyan, Tania Gudu, Carmel Stober, Michalis Kostapanos, Frances Hall, James Galloway, David Jayne

Publikováno v: Rheumatology (Oxford, England)
Rheumatology

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef704aad4fb3ad8bcf251c89776a894c
http://europepmc.org/articles/PMC7928625

132 Investigating the lowest threshold of vascular benefits from LDL lowering with a PCSK9 inhibitor in healthy volunteers – results from the intensity-low study

Autor: Joseph Cheriyan, Ian B. Wilkinson, Paul J. Cacciottolo, Annette Hubsch, Michalis Kostapanos, Holly Pavey

Publikováno v: Stable IHD/Prevention/Hypertension/Lipids.

Background There is a continuous relationship between low density lipoprotein cholesterol (LDL-C) and cardiovascular risk. The cardiovascular benefits of reducing LDL-C in low risk normocholesterolaemic subjects is unknown. The INTENSITY LOW study so

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::17d1f6c6885c95bc4ecdff70e08b5402
https://doi.org/10.1136/heartjnl-2020-bcs.132