Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Michale Bouskila"'
Autor:
Michale Bouskila, Noor Esoof, Laurie Gay, Emily H. Fang, Maria Deak, Michael J. Begley, Lewis C. Cantley, Alan Prescott, Kate G. Storey, Dario R. Alessi
Publikováno v:
Biochemical Journal. 437:157-167
Mutations that truncate the C-terminal non-catalytic moiety of TTBK2 (tau tubulin kinase 2) cause the inherited, autosomal dominant, SCA11 (spinocerebellar ataxia type 11) movement disorder. In the present study we first assess the substrate specific
Publikováno v:
American Journal of Physiology-Endocrinology and Metabolism. 294:E28-E35
Insulin promotes dephosphorylation and activation of glycogen synthase (GS) by inactivating glycogen synthase kinase (GSK) 3 through phosphorylation. Insulin also promotes glucose uptake and glucose 6-phosphate (G-6- P) production, which allosterical
Autor:
Mark Peggie, Lucie Delattre, Adel F. M. Ibrahim, Jørgen Jensen, Peter J. Voshol, Janna A. van Diepen, Kei Sakamoto, Roger W. Hunter, Michale Bouskila
Publikováno v:
Cell Metabolism, 12(5), 456-466
Glycogen synthase (GS), a key enzyme in glycogen synthesis, is activated by the allosteric stimulator glucose-6-phosphate (G6P) and by dephosphorylation through inactivation of GS kinase-3 with insulin. The relative importance of these two regulatory
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c276bb2f7fc863d31a91298701268a57
http://hdl.handle.net/1887/109020
http://hdl.handle.net/1887/109020
Autor:
Michael F. Hirshman, Kei Sakamoto, Laurie J. Goodyear, Adel F. M. Ibrahim, Mark Peggie, Michale Bouskila, Jørgen Arendt Jensen
Publikováno v:
The FASEB Journal. 22
Autor:
Doris Cassio, Virginie E. Bender, Stephan Chevalier, Elodie Boissel, Aurelien Mignot, Laetitia Nicaise, Christine P. Biagini, Michale Bouskila, Fabien Blazy, Françoise Borde
Publikováno v:
Toxicology in vitro : an international journal published in association with BIBRA. 20(6)
The cytotoxicity profile of various chemical entities was evaluated using two in vitro hepatocyte models. Liverbeads is a cryopreserved model consisting of primary hepatocytes entrapped in alginate beads. WIF-B9 is a hybrid cell line obtained by fusi