The conjugates of 5'-deoxy-5-fluorocytidine and hydroxycinnamic acids - synthesis, anti-pancreatic cancer activity and molecular docking studies.

Autor: Cybulski M; Pharmacy, Cosmetic Chemistry and Biotechnology Research Group, Łukasiewicz Research Network-Industrial Chemistry Institute Rydygiera 8 01-793 Warsaw Poland olga.michalak@ichp.lukasiewicz.gov.pl marcin.cybulski@ichp.lukasiewicz.gov.pl +48 453 056 175 +48 453 056 177., Zaremba-Czogalla M; Department of Lipids and Liposomes, Faculty of Biotechnology, University of Wroclaw Fryderyka Joliot-Curie 14a 50-383 Wroclaw Poland., Trzaskowski B; Chemical and Biological Systems Simulation Laboratory, Center of New Technologies, University of Warsaw Banacha 2c 02-097 Warsaw Poland., Kubiszewski M; Pharmaceutical Analysis Laboratory, Łukasiewicz Research Network-Industrial Chemistry Institute Rydygiera 8 01-793 Warsaw Poland., Tobiasz J; Pharmacy, Cosmetic Chemistry and Biotechnology Research Group, Łukasiewicz Research Network-Industrial Chemistry Institute Rydygiera 8 01-793 Warsaw Poland olga.michalak@ichp.lukasiewicz.gov.pl marcin.cybulski@ichp.lukasiewicz.gov.pl +48 453 056 175 +48 453 056 177., Jaromin A; Department of Lipids and Liposomes, Faculty of Biotechnology, University of Wroclaw Fryderyka Joliot-Curie 14a 50-383 Wroclaw Poland., Krzeczyński P; Pharmacy, Cosmetic Chemistry and Biotechnology Research Group, Łukasiewicz Research Network-Industrial Chemistry Institute Rydygiera 8 01-793 Warsaw Poland olga.michalak@ichp.lukasiewicz.gov.pl marcin.cybulski@ichp.lukasiewicz.gov.pl +48 453 056 175 +48 453 056 177., Gubernator J; Department of Lipids and Liposomes, Faculty of Biotechnology, University of Wroclaw Fryderyka Joliot-Curie 14a 50-383 Wroclaw Poland., Michalak O; Pharmacy, Cosmetic Chemistry and Biotechnology Research Group, Łukasiewicz Research Network-Industrial Chemistry Institute Rydygiera 8 01-793 Warsaw Poland olga.michalak@ichp.lukasiewicz.gov.pl marcin.cybulski@ichp.lukasiewicz.gov.pl +48 453 056 175 +48 453 056 177.

Publikováno v: RSC advances [RSC Adv] 2024 Apr 23; Vol. 14 (19), pp. 13129-13141. Date of Electronic Publication: 2024 Apr 23 (Print Publication: 2024).

The Conjugates of Indolo[2,3- b ]quinoline as Anti-Pancreatic Cancer Agents: Design, Synthesis, Molecular Docking and Biological Evaluations.

Autor: Cybulski M; Pharmacy, Cosmetic Chemistry and Biotechnology Research Group, Łukasiewicz Research Network-Industrial Chemistry Institute, 01-793 Warsaw, Poland., Sidoryk K; Pharmacy, Cosmetic Chemistry and Biotechnology Research Group, Łukasiewicz Research Network-Industrial Chemistry Institute, 01-793 Warsaw, Poland., Zaremba-Czogalla M; Department of Lipids and Liposomes, Faculty of Biotechnology, University of Wroclaw, 50-383 Wroclaw, Poland., Trzaskowski B; Chemical and Biological Systems Simulation Lab, Center of New Technologies, University of Warsaw, 02-097 Warsaw, Poland., Kubiszewski M; Pharmaceutical Analysis Laboratory, Łukasiewicz Research Network-Industrial Chemistry Institute, 01-793 Warsaw, Poland., Tobiasz J; Pharmacy, Cosmetic Chemistry and Biotechnology Research Group, Łukasiewicz Research Network-Industrial Chemistry Institute, 01-793 Warsaw, Poland., Jaromin A; Department of Lipids and Liposomes, Faculty of Biotechnology, University of Wroclaw, 50-383 Wroclaw, Poland., Michalak O; Pharmacy, Cosmetic Chemistry and Biotechnology Research Group, Łukasiewicz Research Network-Industrial Chemistry Institute, 01-793 Warsaw, Poland.

Publikováno v: International journal of molecular sciences [Int J Mol Sci] 2024 Feb 22; Vol. 25 (5). Date of Electronic Publication: 2024 Feb 22.

Antioxidant activity of novel diosgenin derivatives: Synthesis, biological evaluation, and in silico ADME prediction.

Autor: Michalak O; Department of Pharmacy, Cosmetic Chemistry and Biotechnology, Team of Chemistry, Łukasiewicz Research Network-Industrial Chemistry Institute, 8 Rydygiera Str., 01-793 Warsaw, Poland. Electronic address: olga.michalak@ichp.pl., Krzeczyński P; Department of Pharmacy, Cosmetic Chemistry and Biotechnology, Team of Chemistry, Łukasiewicz Research Network-Industrial Chemistry Institute, 8 Rydygiera Str., 01-793 Warsaw, Poland. Electronic address: piotr.krzeczynski@ichp.pl., Jaromin A; Department of Lipids and Liposomes, Faculty of Biotechnology, University of Wrocław, 14a Joliot-Curie Street, 50-383 Wrocław, Poland. Electronic address: anna.jaromin@uwr.edu.pl., Cmoch P; Institute of Organic Chemistry Polish Academy of Sciences, 44/52 Kasprzaka Str., 01-224 Warsaw, Poland. Electronic address: piotr.cmoch@icho.edu.pl., Cybulski M; Department of Pharmacy, Cosmetic Chemistry and Biotechnology, Team of Chemistry, Łukasiewicz Research Network-Industrial Chemistry Institute, 8 Rydygiera Str., 01-793 Warsaw, Poland. Electronic address: marcin.cybulski@ichp.pl., Trzcińska K; Analytical Department, Łukasiewicz Research Network-Industrial Chemistry Institute, 8 Rydygiera Str., 01-793 Warsaw, Poland. Electronic address: kinga.trzcinska@ichp.pl., Miszta P; Faculty of Chemistry, Biological and Chemical Research Centre, University of Warsaw, 02-093 Warsaw, Poland. Electronic address: pmiszta@chem.uw.edu.pl., Mehta P; Faculty of Chemistry, Biological and Chemical Research Centre, University of Warsaw, 02-093 Warsaw, Poland. Electronic address: pakhurimehta@gmail.com., Gubernator J; Department of Lipids and Liposomes, Faculty of Biotechnology, University of Wrocław, 14a Joliot-Curie Street, 50-383 Wrocław, Poland. Electronic address: jerzy.gubernator@uwr.edu.pl., Filipek S; Faculty of Chemistry, Biological and Chemical Research Centre, University of Warsaw, 02-093 Warsaw, Poland. Electronic address: slawomir.filipek@biomodellab.net.

Publikováno v: Steroids [Steroids] 2022 Dec; Vol. 188, pp. 109115. Date of Electronic Publication: 2022 Sep 23.

Alkylation of thymine with 1,2-dibromoethane

Autor: Nawrot, B, Michalak, O, Olejniczak, S, Wieczorek, M.W, Lis, T, Stec, W.J

Publikováno v: In Tetrahedron 2001 57(18):3979-3985

Mucin 1 as a Molecular Target of a Novel Diisoquinoline Derivative Combined with Anti-MUC1 Antibody in AGS Gastric Cancer Cells.

Autor: Gornowicz A; Department of Biotechnology, Medical University of Bialystok, 15-222 Bialystok, Poland., Szymanowski W; Department of Biotechnology, Medical University of Bialystok, 15-222 Bialystok, Poland., Bielawski K; Department of Synthesis and Technology of Drugs, Medical University of Bialystok, 15-222 Bialystok, Poland., Kałuża Z; Institute of Organic Chemistry, Polish Academy of Sciences, 01-224 Warsaw, Poland., Michalak O; Department of Pharmacy, Cosmetic Chemistry and Biotechnology, Team of Chemistry, Łukasiewicz Research Network-Industrial Chemistry Institute, 01-793 Warsaw, Poland., Bielawska A; Department of Biotechnology, Medical University of Bialystok, 15-222 Bialystok, Poland.

Publikováno v: Molecules (Basel, Switzerland) [Molecules] 2021 Oct 28; Vol. 26 (21). Date of Electronic Publication: 2021 Oct 28.