Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Michal Zucker"'
Autor:
Michal Zucker, Ariella Zivelin, Meytal Landau, Ophira Salomon, Gili Kenet, Frederic Bauduer, Michel Samama, Jacqueline Conard, Marie-Hélène Denninger, Abu-Samra Hani, Micheline Berruyer, Donald Feinstein, Uri Seligsohn
Publikováno v:
Haematologica, Vol 92, Iss 10 (2007)
Background and Objectives Factor XI (FXI) deficiency is a rare autosomal recessive disorder, the main manifestation of which is injury-related bleeding. The disorder is rare in most populations, but common among Jews in whom two mutations, E117X and
Externí odkaz:
https://doaj.org/article/47f3ce0a707347499acff32ff6842104
Autor:
Uri Seligsohn, Antoinette Blair, Matthew T. Rondina, Michal Zucker, Ronit Mor-Cohen, Colin K. Grissom, Robert A. Campbell, Samuel M. Brown
Publikováno v:
Journal of thrombosis and thrombolysis. 47(2)
BACKGROUND. Coagulation Factor XI (FXI) contributes to the pathobiology of sepsis-associated thrombosis and is a target for new therapeutics. Through cleavage of disulfide bonds, FXI becomes reduced (rFXI), accelerating intrinsic coagulation cascade
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b00f0ac776cf9ab5f6093f1f5ffe46a9
https://pubmed.ncbi.nlm.nih.gov/30600428
https://pubmed.ncbi.nlm.nih.gov/30600428
Publikováno v:
Annals of Tourism Research Empirical Insights, Vol 4, Iss 2, Pp 100108- (2023)
Externí odkaz:
https://doaj.org/article/009e30368b274895ada854d9f5e55b67
Publikováno v:
Blood cells, moleculesdiseases. 69
Background The structure and function of platelet factor XI (FXI) protein and the presence of F11 mRNA in platelets are controversial. Although platelets are anucleated cells they contain spliceosome components and pre-mRNAs. Three platelet proteins
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1626462eb9590502640269ea44e47bbd
https://pubmed.ncbi.nlm.nih.gov/28760385
https://pubmed.ncbi.nlm.nih.gov/28760385
Publikováno v:
Journal of thrombosis and haemostasis : JTH. 14(11)
Essentials Reduction of three disulfide bonds in factor (F) XI enhances chromogenic substrate cleavage. We measured FXI activity upon reduction and identified a bond involved in the enhanced activity. Reduction of FXI augments FIX cleavage, probably
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4844d4f685e2e805a83fd6dcb51e49b4
https://pubmed.ncbi.nlm.nih.gov/27575053
https://pubmed.ncbi.nlm.nih.gov/27575053
Autor:
David M. Steinberg, David Varon, Uri Seligsohn, Ariella Zivelin, Ophira Salomon, Michal Zucker
Publikováno v:
Thrombosis and Haemostasis. 105:269-273
SummaryFactor XI (FXI) plays a dual role in haemostasis and thrombosis. It contributes to thrombin generation and promotes inhibition of fibrinolysis. Severe FXI deficiency was shown to confer protection against arterial and venous thrombosis in anim
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5865684ba38697631a362f96d4321239
https://doi.org/10.1160/th10-05-0307
https://doi.org/10.1160/th10-05-0307
Publikováno v:
Journal of Thrombosis and Haemostasis. 5:O-S
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::58ad3edaf78c1c23c64a86d518aea128
https://doi.org/10.1111/j.1538-7836.2007.tb00089.x
https://doi.org/10.1111/j.1538-7836.2007.tb00089.x
Publikováno v:
Psychiatry Research. 112:251-256
The intraneuronal uptake of monoamines into brain synaptic vesicles is mediated by the vesicular monoamine transporter (VMAT2). This transporter plays a major role in monoamine storage and quantal release. Recently we demonstrated a high degree of si
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a1d15aea882e2859a90dc5d822a2324e
https://doi.org/10.1016/s0165-1781(02)00223-8
https://doi.org/10.1016/s0165-1781(02)00223-8
Publikováno v:
European Neuropsychopharmacology. 12:343-347
Vesicular monoamine transporter (VMAT2) plays a major role in the synaptic accumulation and release of monoamines. In the present study, we assessed high affinity [(3)H]dihydrotetrabenazine binding to platelet VMAT2 in a group of treated (n = 9) and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::43bbb3d30729695d28de776e7fe0f692
https://doi.org/10.1016/s0924-977x(02)00041-x
https://doi.org/10.1016/s0924-977x(02)00041-x
Publikováno v:
Life Sciences. 69:2311-2317
The present study indicates that human platelets can be used as an accessible peripheral model not only for the plasma membrane serotonin transporter, but also for the vesicular monoamine transporter. The vesicular monoamine transporter (VMAT2) is re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::55e756a15372f3947f992326f7b43233
https://doi.org/10.1016/s0024-3205(01)01301-7
https://doi.org/10.1016/s0024-3205(01)01301-7