Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Michal Zimecki"'
Publikováno v:
Frontiers in Chemistry, Vol 9 (2021)
During inflammation neutrophils become activated and segregate neutrophil serine proteases (NSPs) to the surrounding environment in order to support a natural immune defense. However, an excess of proteolytic activity of NSPs can cause many complicat
Externí odkaz:
https://doaj.org/article/9e010d1b5c704a3abf66bcde79779acf
Publikováno v:
Frontiers in Immunology, Vol 8 (2017)
Much progress has been achieved to elucidate the function of lactoferrin (LTF), an iron-binding glycoprotein, in the milieu of immune functionality. This review represents a unique examination of LTF toward its importance in physiologic homeostasis a
Externí odkaz:
https://doaj.org/article/4c1c3311e7a14d7fabb104b897c2aeb9
Autor:
Steffen Eipper, Robin Steiner, Adam Lesner, Marcin Sienczyk, David Palesch, Marc-Eric Halatsch, Ewa Zaczynska, Christopher Heim, Marcus D Hartmann, Michal Zimecki, Christian Rainer Wirtz, Timo Burster
Publikováno v:
PLoS ONE, Vol 11, Iss 3, p e0151509 (2016)
Protease-mediated degradation of proteins is critical in a plethora of physiological processes. Neutrophils secrete serine proteases including cathepsin G (CatG), neutrophile elastase (NE), and proteinase 3 (PR3) together with lactoferrin (LF) as a f
Externí odkaz:
https://doaj.org/article/d3ce30b2596a4d178a0a69b6c596b172
Autor:
Leon Strzadala, Anna Fiedorowicz, Edyta Wysokinska, Ewa Ziolo, Małgorzata Grudzień, Malgorzata Jelen, Krystian Pluta, Beata Morak-Mlodawska, Michal Zimecki, Wojciech Kalas
Publikováno v:
Molecules, Vol 23, Iss 10, p 2443 (2018)
An azaphenothiazine derivative, 6-chloroethylureidoethyldiquino[3,2-b;2′,3′-e][1,4]thiazine (DQT), has recently been shown to exhibit immunosuppressive activities in mouse models. It also inhibited the expression of CXCL10 at the protein level, a
Externí odkaz:
https://doaj.org/article/25a57afd18f44ac39b8941184b3cf559
Publikováno v:
Annals of clinical and laboratory science. 51(3)
The aim of this investigation was to evaluate the property of bovine lactoferrin (LF) in the generation of delayed type hypersensitivity (DTH) as an oral adjuvant during immunization with ovalbumin (OVA) and BCG.LF admixed with OVA or BCG was used fo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::927957639d7c19c5d17a8f895fdeb81d
https://pubmed.ncbi.nlm.nih.gov/34162566
https://pubmed.ncbi.nlm.nih.gov/34162566
Autor:
Krzysztof Kaczmarek, Jolanta Artym, Joanna Bojarska, Barbara Pacholczyk-Sienicka, Joanna Waśko, Ingrid Jelemenska, Wojciech M. Wolf, Martin Breza, Michał Zimecki
Publikováno v:
Pharmaceutics, Vol 16, Iss 8, p 1106 (2024)
The anti-inflammatory, antiviral, and anti-cancer properties, as well as the mechanism of action of cyclo-[Pro-Pro-β3-HoPhe-Phe-] tetrapeptide (denoted as 4B8M), were recently described. The aim of this work was to synthesize and evaluate the immuno
Externí odkaz:
https://doaj.org/article/7fad97f9e46f4960810bada3b0d223b0
Autor:
Michał Zimecki, Jolanta Artym, Maja Kocięba, Ewa Zaczyńska, Angelika Sysak, Marianna Szczypka, Magdalena Lis, Aleksandra Pawlak, Bożena Obmińska-Mrukowicz, Katarzyna Kaleta-Kuratewicz, Aleksandra Zambrowicz, Łukasz Bobak
Publikováno v:
Molecules, Vol 29, Iss 14, p 3254 (2024)
Yolkin, an egg yolk immunoregulatory protein, stimulates the humoral but inhibits the cellular immune response in adult mice. The aim of this investigation was to evaluate the effects of yolkin administration on the immune response using a model of j
Externí odkaz:
https://doaj.org/article/153321340a8749938f69cff6c92179f3
Publikováno v:
Bioconjugate Chemistry. 17:1116-1124
The nonapeptide fragment of the HLA-DR molecule, located in the exposed loop of the beta chain (164-172) and having the sequence VPRSGEVYT, suppresses the immune response. On the basis of the three-dimensional structure of the HLA-DR superdimer, we d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::356f98b18f78fba2ecaea412c33c5c33
https://doi.org/10.1021/bc050360h
https://doi.org/10.1021/bc050360h
