Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Michal Sperber"'
Autor:
Mor Bordeynik-Cohen, Michal Sperber, Lena Ebbers, Naama Messika-Gold, Constanze Krohs, Tal Koffler-Brill, Yael Noy, Ran Elkon, Hans Gerd Nothwang, Karen B. Avraham
Publikováno v:
RNA Biology, Vol 20, Iss 1, Pp 629-640 (2023)
The peripheral and central auditory subsystems together form a complex sensory network that allows an organism to hear. The genetic programs of the two subsystems must therefore be tightly coordinated during development. Yet, their interactions and c
Externí odkaz:
https://doaj.org/article/52292a900357441c8821cdf77955ae5d
Autor:
Kathleen Gwilliam, Michal Sperber, Katherine Perry, Kevin P. Rose, Laura Ginsberg, Nikhil Paladugu, Yang Song, Beatrice Milon, Ran Elkon, Ronna Hertzano
Publikováno v:
Frontiers in Audiology and Otology, Vol 2 (2024)
IntroductionMutations in microRNA-96 (miR-96), a microRNA expressed within the hair cells (HCs) of the inner ear, result in progressive hearing loss in both mouse models and humans. In this study, we present the first HC-specific RNA-sequencing (RNA-
Externí odkaz:
https://doaj.org/article/76a1afa39487424886cff7765775e17c
Autor:
Tomokatsu Udagawa, Patrick J Atkinson, Beatrice Milon, Julia M Abitbol, Yang Song, Michal Sperber, Elvis Huarcaya Najarro, Mirko Scheibinger, Ran Elkon, Ronna Hertzano, Alan G Cheng
Publikováno v:
PLoS Biology, Vol 19, Iss 11, p e3001445 (2021)
Cochlear supporting cells (SCs) are glia-like cells critical for hearing function. In the neonatal cochlea, the greater epithelial ridge (GER) is a mitotically quiescent and transient organ, which has been shown to nonmitotically regenerate SCs. Here
Externí odkaz:
https://doaj.org/article/6257f12c990547c7b8b5062d341a46d0
Autor:
Beatrice Milon, Eldad D. Shulman, Kathy S. So, Christopher R. Cederroth, Erika L. Lipford, Michal Sperber, Jonathan B. Sellon, Heela Sarlus, Gabriela Pregernig, Benjamin Shuster, Yang Song, Sunayana Mitra, Joshua Orvis, Zachary Margulies, Yoko Ogawa, Christopher Shults, Didier A. Depireux, Adam T. Palermo, Barbara Canlon, Joe Burns, Ran Elkon, Ronna Hertzano
Publikováno v:
Cell Reports, Vol 36, Iss 13, Pp 109758- (2021)
Summary: Noise-induced hearing loss (NIHL) results from a complex interplay of damage to the sensory cells of the inner ear, dysfunction of its lateral wall, axonal retraction of type 1C spiral ganglion neurons, and activation of the immune response.
Externí odkaz:
https://doaj.org/article/339f5e676bfd45d480fda7df6c6888d0
Publikováno v:
Proceedings of the Royal Society B: Biological Sciences. 290
Nutrient deprivation (starvation) induced by fasting and hypercaloric regimens are stress factors that can influence cell and tissue homeostasis in mammals. One of the key cellular responses to changes in nutrient availability is the cell survival pa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::07087a10331326a745ed2bdee47c8717
https://doi.org/10.1098/rspb.2023.0407
https://doi.org/10.1098/rspb.2023.0407
Autor:
Michal Sperber, Joseph C. Burns, Didier A. Depireux, Sunayana Mitra, Ronna Hertzano, Kathy S. So, Jonathan B. Sellon, Ran Elkon, Zachary Margulies, Christopher R. Cederroth, Heela Sarlus, Barbara Canlon, Joshua Orvis, Benjamin Shuster, Yoko Ogawa, Erika L. Lipford, Christopher Shults, Beatrice Milon, Eldad David Shulman, Yang Song, Gabriela Pregernig, Adam T. Palermo
Publikováno v:
Cell Reports, Vol 36, Iss 13, Pp 109758-(2021)
Cell reports
Cell reports
SUMMARY Noise-induced hearing loss (NIHL) results from a complex interplay of damage to the sensory cells of the inner ear, dysfunction of its lateral wall, axonal retraction of type 1C spiral ganglion neurons, and activation of the immune response.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f1429b77c1b05708ac2a85c862ceaa7
http://www.sciencedirect.com/science/article/pii/S2211124721012122
http://www.sciencedirect.com/science/article/pii/S2211124721012122
Autor:
Joshua McElwee, Yael Haberman, Joseph C. Maranville, Dror S. Shouval, Ortal Barel, Lael Werner, Michal Sperber, Batia Weiss, Michael Field, Iris Barshack, Yair Anikster, Moran Nunberg, Iddo Vardi, Raz Somech, Gideon Rechavi, Michael Schvimer, Jodie Ouahed, Avishay Lahad, D. Marek-Yagel, Scott B. Snapper
Publikováno v:
Digestive Diseases and Sciences. 63:1192-1199
BACKGROUND: Advances in genomics have facilitated the discovery of monogenic disorders in patients with unique gastro-intestinal phenotypes. Syndromic diarrhea, also called tricho-hepato-enteric (THE) syndrome, results from deleterious mutations in S
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f68b85ce51636d1947d4622f4e87458f
https://doi.org/10.1007/s10620-018-4983-x
https://doi.org/10.1007/s10620-018-4983-x
Autor:
Michal Sperber, Elvis Huarcaya Najarro, Mirko Scheibinger, Ran Elkon, Tomokatsu Udagawa, Beatrice Milon, Julia M. Abitbol, Ronna Hertzano, Yang Song, Patrick J. Atkinson, Alan G. Cheng
Publikováno v:
PLoS Biology, Vol 19, Iss 11, p e3001445 (2021)
PLoS Biology
PLoS Biology
Cochlear supporting cells (SCs) are glia-like cells critical for hearing function. In the neonatal cochlea, the greater epithelial ridge (GER) is a mitotically quiescent and transient organ, which has been shown to nonmitotically regenerate SCs. Here
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::792c18ad38d89d05803e7538c27445ba
https://doi.org/10.1371/journal.pbio.3001445
https://doi.org/10.1371/journal.pbio.3001445
Autor:
Nawsad Alam, Michal Sperber, Ora Schueler-Furman, Dima Kozakov, Orly Marcu, Marc F. Lensink, Emma-Joy Dodson
Publikováno v:
Proteins
Proteins, 2017, Proteins, 85 (3), pp.445-462. ⟨10.1002/prot.25230⟩
Proteins, 2017, Proteins, 85 (3), pp.445-462. ⟨10.1002/prot.25230⟩
CAPRI rounds 28 and 29 included, for the first time, peptide‐receptor targets of three different systems, reflecting increased appreciation of the importance of peptide‐protein interactions. The CAPRI rounds allowed us to objectively assess the p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::66035f1f0096f81abe26056244e18648
https://doi.org/10.1002/prot.25230
https://doi.org/10.1002/prot.25230
Autor:
Maria Belitsky, Haim Avshalom, Hanna Engelberg-Kulka, Ariel Erental, Idan Yelin, Sathish Kumar, Ora Schueler-Furman, Nir London, Michal Sperber
Publikováno v:
Molecular Cell. 41(6):625-635
Escherichia coli (E. coli) mazEF is a toxin-antitoxin (TA) stress-induced module that mediates cell death requiring the quorum-sensing pentapeptide NNWNN designated EDF (extracellular death factor). E. coli toxin MazF is a sequence-specific endoribon
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5bd047ffca924e765cbedbfaea173e2c