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Autor:
Petr Dzubak, Monika Harvanova, Pavla Perlíková, Marian Hajduch, Pawel Znojek, Dalibor Dolezal, Tomáš Elbert, Lenka Slavetinska, Eva Tloušt’ová, Petr Nauš, Jan Hlaváč, Michal Hocek, Kamil Motyka, Aurelie Bourderioux, Gabriela Rylova, Alice Nova, Michal Siler
Publikováno v:
Cancer Research. 77:5100-5100
7-(2-Thienyl)-7-deazaadenosine (AB61) showed nanomolar cytotoxic activities against various cancer cell lines but only mild (micromolar) activities against normal fibroblasts. The selectivity of AB61 was found to be due to inefficient phosphorylation