Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Michal Shoshkes-Carmel"'
Autor:
Michal Shoshkes-Carmel
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 17, Iss 5, Pp 697-701 (2024)
Telocytes are unique mesenchymal cells characterized by multiple remarkably long cytoplasmic extensions that extend hundreds of micron away from the cell body. Through these extensions, telocytes establish a 3-dimensional network by connecting with o
Externí odkaz:
https://doaj.org/article/5fc245de730345f8b8d8864f2158515d
Autor:
Ihab Ansari, Llorenç Solé-Boldo, Meshi Ridnik, Julian Gutekunst, Oliver Gilliam, Maria Korshko, Timur Liwinski, Birgit Jickeli, Noa Weinberg-Corem, Michal Shoshkes-Carmel, Eli Pikarsky, Eran Elinav, Frank Lyko, Yehudit Bergman
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-18 (2023)
Abstract TET2/3 play a well-known role in epigenetic regulation and mouse development. However, their function in cellular differentiation and tissue homeostasis remains poorly understood. Here we show that ablation of TET2/3 in intestinal epithelial
Externí odkaz:
https://doaj.org/article/cbb5a9ce71a14585b4a2f3a138ff783a
Autor:
Keren Bahar Halpern, Hassan Massalha, Rachel K. Zwick, Andreas E. Moor, David Castillo-Azofeifa, Milena Rozenberg, Lydia Farack, Adi Egozi, Dan R. Miller, Inna Averbukh, Yotam Harnik, Noa Weinberg-Corem, Frederic J. de Sauvage, Ido Amit, Ophir D. Klein, Michal Shoshkes-Carmel, Shalev Itzkovitz
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-12 (2020)
Epithelial gene expression has been shown to be zonated along the crypt-villus axis, but mechanisms shaping this spatial variability were unknown. Here, Bahar Halpern et al. uncover zonation of mesenchymal cells, including Lgr5+ telocytes, which regu
Externí odkaz:
https://doaj.org/article/06a4059134d14359ba2c09cd1b2ad006
Autor:
Moriya Shushan, Michal Shoshkes-Carmel
Publikováno v:
Life, Vol 12, Iss 2, p 176 (2022)
We recently identified a FOXL1+ intestinal subepithelial network of telocytes (TCs) without which epithelial stem and progenitor cells cannot proliferate and support regeneration. In addition to FOXL1 lineage cell distribution along the intestinal ep
Externí odkaz:
https://doaj.org/article/d3142889378b4d4ea580e860fad8f04a
Autor:
Reina Aoki, Michal Shoshkes-Carmel, Nan Gao, Soona Shin, Catherine L. May, Maria L. Golson, Adam M. Zahm, Michael Ray, Caroline L. Wiser, Christopher V.E. Wright, Klaus H. Kaestner
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 2, Iss 2, Pp 175-188 (2016)
Background & Aims: Intestinal epithelial stem cells that express leucine-rich repeat-containing G-protein coupled receptor 5 (Lgr5) and/or B cell specific Moloney murine leukemia virus integration site 1 (Bmi1) continuously replicate and generate dif
Externí odkaz:
https://doaj.org/article/9aa31af81af344169c10335fefc358e5
Autor:
Nofar Rosenberg, Matthias Van Haele, Tali Lanton, Neta Brashi, Zohar Bromberg, Hanan Adler, Hilla Giladi, Amnon Peled, Daniel S. Goldenberg, Jonathan H. Axelrod, Alina Simerzin, Chofit Chai, Mor Paldor, Auerlia Markezana, Dayana Yaish, Zohar Shemulian, Dvora Gross, Shanny Barnoy, Maytal Gefen, Osher Amran, Sofie Claerhout, Mirian Fernández-Vaquero, María García-Beccaria, Danijela Heide, Michal Shoshkes-Carmel, Dirk Schmidt Arras, Sharona Elgavish, Yuval Nevo, Hadar Benyamini, Janina E.E. Tirnitz-Parker, Aranzazu Sanchez, Blanca Herrera, Rifaat Safadi, Klaus H. Kaestner, Stefan Rose-John, Tania Roskams, Mathias Heikenwalder, Eithan Galun
Publikováno v:
Journal of Hepatology, 77(6), 1631-1641. Elsevier Science
BACKGROUND AND AIMS: Primary liver cancers include: Hepatocellular carcinoma (HCC), intrahepatic cholangiocarcinoma (CCA) and combined HCC-CCA tumors (cHCC-CCA). It has been suggested, but not unequivocally proven, that hepatic progenitor cells (HPCs
Autor:
Marco Canella, Simcha Nalick, Noa Corem, Amal Gharbi, Ittai Ben-Porath, Michal Shoshkes-Carmel
In multiple tissues, stem cell proliferation driving tissue regeneration is dependent on Wnt/β-catenin signaling, but the identity of the niche cells providing the Wnt proteins is not resolved. Here, we show that telocytes, unique interstitial cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::81e0db9b92dde8c42f86e94c7f877d01
https://doi.org/10.1101/2023.05.17.541070
https://doi.org/10.1101/2023.05.17.541070
Publikováno v:
Journal of Visualized Experiments.
Autor:
Moriya Shushan, Michal Shoshkes-Carmel
Publikováno v:
Life (Basel, Switzerland). 12(2)
We recently identified a FOXL1+ intestinal subepithelial network of telocytes (TCs) without which epithelial stem and progenitor cells cannot proliferate and support regeneration. In addition to FOXL1 lineage cell distribution along the intestinal ep
Autor:
Nofar Rosenberg, Matthias Van Haele, Maria Garcia Beccaria, Mirian Fernández-Vaquero, Danijela Heide, Neta Barashi, Amnon Peled, Yuval Nevo, Shrona Elgavish, Dirk Schmist-Arras, Hanan Edler, Alina Simerzin, Michal Shoshkes-Carmel, Klaus Kaestner, Hilla Giladi, Stefan Rose-John, Tania Roskams, Mathias Heikenwälder, Eithan Galun
Publikováno v:
Journal of Hepatology. 77:S47