Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Michal Scur"'
Autor:
Marinella Pinelli, Stephanie Makdissi, Michal Scur, Brendon D. Parsons, Kristi Baker, Anthony Otley, Brad MacIntyre, Huong D. Nguyen, Peter K. Kim, Andrew W. Stadnyk, Francesca Di Cara
Publikováno v:
Cell Death and Disease, Vol 15, Iss 7, Pp 1-19 (2024)
Abstract Intestinal epithelial cells line the luminal surface to establish the intestinal barrier, where the cells play essential roles in the digestion of food, absorption of nutrients and water, protection from microbial infections, and maintaining
Externí odkaz:
https://doaj.org/article/48e7ee7072a0461597d0d132b55cff6c
Autor:
Brendon D. Parsons, Daniel Medina-Luna, Michal Scur, Marinella Pinelli, Gayani S. Gamage, Rebecca A. Chilvers, Yannick Hamon, Ibrahim H.I. Ahmed, Stéphane Savary, Andrew P. Makrigiannis, Nancy E. Braverman, Juan F. Rodriguez-Alcazar, Eicke Latz, Tobias K. Karakach, Francesca Di Cara
Publikováno v:
Cell Reports, Vol 43, Iss 2, Pp 113744- (2024)
Summary: Peroxisome biogenesis disorders (PBDs) represent a group of metabolic conditions that cause severe developmental defects. Peroxisomes are essential metabolic organelles, present in virtually every eukaryotic cell and mediating key processes
Externí odkaz:
https://doaj.org/article/a066126b3d614f75b0ca3c0d6ec4d610
Autor:
Michal Scur, Ahmad Bakur Mahmoud, Sayanti Dey, Farah Abdalbarri, Iona Stylianides, Daniel Medina-Luna, Gayani S. Gamage, Aaron Woblistin, Alexa N. M. Wilson, Haggag S. Zein, Ashley Stueck, Andrew Wight, Oscar A. Aguilar, Francesca Di Cara, Brendon D. Parsons, Mir Munir A. Rahim, James R. Carlyle, Andrew P. Makrigiannis
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-20 (2022)
Alveolar macrophages (AM) in the lungs maintain surfactant during homeostasis and respond to infectious pathogens. Here the authors show that in the absence of NKR-P1B, pneumococcal infection is more severe because KO AM have increased rates of lipid
Externí odkaz:
https://doaj.org/article/ca6a2921570140329609abd0d7a69abd
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Our understanding of the C-type lectin-like receptors (CTLRs) and their functions in immunity have continued to expand from their initial roles in pathogen recognition. There are now clear examples of CTLRs acting as scavenger receptors, sensors of c
Externí odkaz:
https://doaj.org/article/09945eee95c44153864c0d61ea51df9b
Autor:
Haggag S. Zein, Elias Abou-Samra, Michal Scur, Alex Gutsol, Clayton W. Hall, Bishal Dasgupta, Lara Gharibeh, Turki Abujamel, Daniel Medina-Luna, Gayani S. Gamage, Tessa J. Pelino, Mona Nemer, Mir Munir A. Rahim, Alexander Steinle, Brendon D. Parsons, Andrew P. Makrigiannis
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-18 (2022)
Abstract The C-type lectin-related protein, Clr-f, encoded by Clec2h in the mouse NK gene complex (NKC), is a member of a family of immune regulatory lectins that guide immune responses at distinct tissues of the body. Clr-f is highly expressed in th
Externí odkaz:
https://doaj.org/article/def7019997cf41cd84054dbbb63b9616
Autor:
Anu S. Nath, Brendon D. Parsons, Stephanie Makdissi, Rebecca L. Chilvers, Yizhu Mu, Ceileigh M. Weaver, Irene Euodia, Katherine A. Fitze, Juyang Long, Michal Scur, Duncan P. Mackenzie, Andrew P. Makrigiannis, Nicolas Pichaud, Luc H. Boudreau, Andrew J. Simmonds, Christine A. Webber, Beata Derfalvi, Yannick Hamon, Richard A. Rachubinski, Francesca Di Cara
Publikováno v:
Cell Reports
Cell Reports, 2022, 38 (9), pp.110433. ⟨10.1016/j.celrep.2022.110433⟩
Cell Reports, 2022, 38 (9), pp.110433. ⟨10.1016/j.celrep.2022.110433⟩
International audience; Phagocytosis, signal transduction, and inflammatory responses require changes in lipid metabolism. Peroxisomes have key roles in fatty acid homeostasis and in regulating immune function. We find that Drosophila macrophages lac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4369b37024de44921a1e06b281ef7e1a
https://hal-amu.archives-ouvertes.fr/hal-03763652/document
https://hal-amu.archives-ouvertes.fr/hal-03763652/document
Autor:
Haggag S, Zein, Elias, Abou-Samra, Michal, Scur, Alex, Gutsol, Clayton W, Hall, Bishal, Dasgupta, Lara, Gharibeh, Turki, Abujamel, Daniel, Medina-Luna, Gayani S, Gamage, Tessa J, Pelino, Mona, Nemer, Mir Munir A, Rahim, Alexander, Steinle, Brendon D, Parsons, Andrew P, Makrigiannis
Publikováno v:
Scientific reports. 12(1)
The C-type lectin-related protein, Clr-f, encoded by Clec2h in the mouse NK gene complex (NKC), is a member of a family of immune regulatory lectins that guide immune responses at distinct tissues of the body. Clr-f is highly expressed in the kidney;
Autor:
Daniel Medina-Luna, Gayani Gamage, Michal Scur, Haggah Zein, Brendon Parsons, Andrew P. Makrigiannis
Publikováno v:
Cancer Research. 82:2111-2111
Introduction: Immunological memory has long been exclusively attributed to T and B lymphocytes; however, we now know that natural killer (NK) cells also possess an analogous function. Studies of Rag-1-deficient mice (Rag1-/-), which lack T and B cell
Autor:
Mir Munir A. Rahim, Ahmad Bakur Mahmoud, James R. Carlyle, Sergey Pyatibrat, Michal Scur, Megan M. Tu, Andrew P. Makrigiannis, Elias Abou-Samra, Arthur Mortha, Oscar A. Aguilar, Zachary Hickey, Jeffrey Francispillai
Publikováno v:
Cell Mol Immunol
Helper-type innate lymphoid cells (ILC) play an important role in intestinal homeostasis. Members of the NKR-P1 gene family are expressed in various innate immune cells, including natural killer (NK) cells, and their cognate Clr ligand family members
Critical role for the Ly49 family of class I MHC receptors in adaptive natural killer cell responses
Autor:
Andrew Wight, Mir Munir A. Rahim, Subash Sad, Megan M. Tu, Andrew P. Makrigiannis, Michal Scur, Ahmad Bakur Mahmoud
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 115(45)
Adaptive natural killer (NK) cell memory represents a new frontier in immunology. Work over the last decade has discovered and confirmed the existence of NK cells with antigen-specific memories, which had previously been considered a unique property