Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Michal S. Hallside"'
Autor:
Martin Hutchings, Amber L. Thompson, Jack L. Sutro, Michal S. Hallside, Jonathan W. Burton, Erin D. Shepherd
Publikováno v:
Tetrahedron. 76:130981
The jatrophane class of natural products exhibit a wide range of biological activities with certain members of this family of complex sesquiterpenes being P-glycoprotein inhibitors. Considerable attention has been paid to the synthesis of biologicall
Autor:
Michal S. Hallside, Leo Marx, Simon J. Sprague, Amber L. Thompson, Angus W. J. Logan, Jonathan W. Burton, Vincenzo Garzya, Robert W. Foster
Publikováno v:
Organic Letters. 16:4078-4081
A mild, diastereoselective synthesis of fused lactone-pyrrolidinones using an oxidative radical cyclization is reported. The methodology is demonstrated in a formal synthesis of (-)-salinosporamide A.
Publikováno v:
Organic Letters
A synthesis of carolacton, a myxobacterial natural product that has profound effects on Streptococcus mutans biofilms, is reported. The synthesis proceeds via a longest linear sequence of 14 steps from an Evans β-ketoimide and enabled preliminary ev
Publikováno v:
Organic Letters. 14:2940-2943
Manganese(III) acetate mediated oxidative radical cyclizations have been used to synthesize a range of densely functionalized and sterically congested cyclopentane-lactones. A number of the resulting lactones contain vicinal all-carbon quaternary ste
Autor:
Amber L. Thompson, Leo Marx, Jonathan W. Burton, Robert W. Foster, Vincenzo Garzya, Angus W. J. Logan, Simon J. Sprague, Michal S. Hallside
Publikováno v:
ChemInform. 46
A mild methodology is developed for the synthesis of a range of fused bicyclic lactone-pyrrolidinones.
Publikováno v:
ChemInform. 45
A synthesis of carolacton, a myxobacterial natural product that has profound effects on Streptococcus mutans biofilms, is reported. The synthesis proceeds via a longest linear sequence of 14 steps from an Evans β-ketoimide and enabled preliminary ev
Publikováno v:
ChemInform. 43
Using this method a number of sterically congested [3.3.0]-bicyclic γ-lactones containing vicinal all-carbon quaternary stereocenters can be prepared.
Publikováno v:
Tetrahedron. 66:2768
0040-4020/$ – see front matter 2010 Elsevier Ltd. doi:10.1016/j.tet.2010.02.016 The authors inadvertently omitted to reference important work on the oxidative radical cyclisations of malonates bearing allylsilanes, mediated by ferrocenium hexafluor