Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Michal Rudnik"'
Autor:
Mara Stellato, Matthias Dewenter, Michal Rudnik, Amela Hukara, Çagla Özsoy, Florian Renoux, Elena Pachera, Felix Gantenbein, Petra Seebeck, Siim Uhtjaerv, Elena Osto, Daniel Razansky, Karin Klingel, Joerg Henes, Oliver Distler, Przemysław Błyszczuk, Gabriela Kania
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-15 (2023)
The role of the transcription factor Fosl-2 in promoting myocardial fibrosis, arrhythmias and aberrant response to stress under immunofibrotic conditions is described using an in vivo mouse model and human cardiac fibroblasts.
Externí odkaz:
https://doaj.org/article/ff374a3b12b64c5493c7766311f21e33
Autor:
Mara Stellato, Matthias Dewenter, Michal Rudnik, Amela Hukara, Çagla Özsoy, Florian Renoux, Elena Pachera, Felix Gantenbein, Petra Seebeck, Siim Uhtjaerv, Elena Osto, Daniel Razansky, Karin Klingel, Joerg Henes, Oliver Distler, Przemysław Błyszczuk, Gabriela Kania
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-1 (2023)
Externí odkaz:
https://doaj.org/article/65251c0cfd2949a9a9955de755ce0884
Autor:
Przemyslaw Blyszczuk, Gabriela Kania, Oliver Distler, Tonja Mertelj, Filip Rolski, Suzana Jordan, Michal Rudnik, Mara Stellato
Publikováno v:
Arthritis & Rheumatology. 73:1720-1730
Objective Systemic sclerosis (SSc) is characterized by dysregulation of type I interferon (IFN) signaling. CD52 is known for its immunosuppressive functions in T cells. This study was undertaken to investigate the role of CD52 in monocyte adhesion an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a6898ea068e7e7f82a65e2936fe258ef
https://doi.org/10.1002/art.41737
https://doi.org/10.1002/art.41737
Autor:
Irina Agarkova, Nadezhda Rotankova, Michal Rudnik, Silvan Strebel, Olga Zimmermannova, Andre Rosa, Fabio F. Rosa, Wolfgang Moritz, Carlos-Filipe Pereira, Christiana F. Pires
Publikováno v:
Cancer Research. 83:4550-4550
Immunotherapy has brought hope for cancer treatment, but its clinical success remains limited. Recently, overexpression of the transcription factors PU.1, IRF8 and BATF3 (PIB) was shown to induce direct reprogramming of tumor cells into antigen-prese
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::eecedf44f5d13bca96a260b911f721ee
https://doi.org/10.1158/1538-7445.am2023-4550
https://doi.org/10.1158/1538-7445.am2023-4550
Autor:
Michal Rudnik, Ozlem Yavaş Grining, Simon Hutter, Frauke Greve, Daniela Ortiz Franyuti, Ramona Matheis, Ekaterina Breous-Nystrom, Olivier Frey
Publikováno v:
Cancer Research. 83:2747-2747
The superior clinical therapeutic effects and broad applications of bispecific T cell engagers (BiTEs) has transformed treatment strategies in oncology. While benefits of the novel immunotherapies are indisputable, the safety aspects require to be in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fe5a21a32cdb2dad4aa70b499c7604e2
https://doi.org/10.1158/1538-7445.am2023-2747
https://doi.org/10.1158/1538-7445.am2023-2747
Autor:
Michal Rudnik, Özlem Yavaş Grining, Nadezhda Rotankova, Silvan Strebel, Francesca Chiovaro, Olivier Frey, Irina Agarkova, Wolfgang Moritz
Publikováno v:
Cancer Research. 83:4558-4558
Emerging studies have demonstrated that innate immune checkpoints, regulating Tumor-associated Macrophage (TAM) phagocytic activity, play a crucial role in immune escape and survival of cancer cells. CD47-SIRPα axis is the best studied example of th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::449cc6bb210f3bc39737170109515bee
https://doi.org/10.1158/1538-7445.am2023-4558
https://doi.org/10.1158/1538-7445.am2023-4558
Autor:
Petra Seebeck, Przemyslaw Blyszczuk, Matthias Dewenter, Michal Rudnik, Oliver Distler, Gabriela Kania, Mara Stellato, Florian Renoux, Elena Osto, E. Pachera
Publikováno v:
Oral Presentations.
Background Cardiac dysfunction is a significant cause of mortality in SSc due to inflammation, vasculopathy and fibrosis. In fibrotic conditions, the excessive number of fibroblasts, myofibroblasts and extracellular matrix in the myocardium may direc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::18846a43a08dcc101e65ccb7a0d9289c
https://doi.org/10.1136/annrheumdis-2019-eular.6403
https://doi.org/10.1136/annrheumdis-2019-eular.6403
Autor:
Michal Rudnik, Gabriela Kania, Carol Feghali-Bostwick, Przemyslaw Blyszczuk, Mara Stellato, Oliver Distler, Karin Klingel, Jörg Henes
Publikováno v:
Oral Presentations.
Background During the course of systemic sclerosis (SSc), infiltration of inflammatory cells, including monocytes, into the organs is a major process leading to fatal fibrosis, remodelling and organ dysfunction. CD52 protein is highly expressed on CD
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8c07a0397839396a1da7c0e0fcd0b5c0
https://doi.org/10.1136/annrheumdis-2019-eular.5952
https://doi.org/10.1136/annrheumdis-2019-eular.5952
Systemic sclerosis (SSc) is an autoimmune fibrotic disease of unknown aetiology that is characterized by vascular changes in the skin and visceral organs. Autologous haematopoietic stem cell transplantation can improve skin and organ fibrosis in pati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c3a63d786b738155d9de3cacd61552f5
https://www.zora.uzh.ch/id/eprint/170632/
https://www.zora.uzh.ch/id/eprint/170632/
Publikováno v:
Annals of the Rheumatic Diseases. 80:442.2-443
Background:Systemic sclerosis (SSc) is associated with an interferon (IFN) signature, which is defined by a higher expression of IFN-stimulated genes (mainly in response to IFNα). Histone deacetylases (HDACs) are a family of epigenetic modifiers med
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::15be03a38fec05403d54fe4275d3ea89
https://doi.org/10.1136/annrheumdis-2021-eular.2869
https://doi.org/10.1136/annrheumdis-2021-eular.2869