Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Michal R. Gdula"'
Autor:
Michal R. Gdula, Tatyana B. Nesterova, Greta Pintacuda, Jonathan Godwin, Ye Zhan, Hakan Ozadam, Michael McClellan, Daniella Moralli, Felix Krueger, Catherine M. Green, Wolf Reik, Skirmantas Kriaucionis, Edith Heard, Job Dekker, Neil Brockdorff
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-14 (2019)
The inactive X chromosome (Xi) has an atypical structure, with global loss of TADs, A/B compartments and formation of mega-domains. Here the authors show that the non-canonical SMC family protein, SmcHD1, important for developmental gene silencing on
Externí odkaz:
https://doaj.org/article/9651dc44fd574c31817692a66b9637db
Autor:
Tatyana B. Nesterova, Arne W. Mould, Neil Brockdorff, Yoko Koseki, Lothar Schermelleh, Haruhiko Koseki, Manabu Nakayama, Mafalda Almeida, Andrea Cerase, Osamu Masui, Cassandravictoria Innocent, David Brown, Greta Pintacuda, Michal R. Gdula
Publikováno v:
Science. 356:1081-1084
Polycomb steps to inactivate X XX females silence one of their X chromosomes. This involves a process whereby a noncoding RNA known as Xist coats one of the X chromosomes and recruits chromatin silencing factors. The Polycomb complexes PRC1 and PRC2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d0f1396edb102306ff07b7b0eba61449
https://doi.org/10.1126/science.aal2512
https://doi.org/10.1126/science.aal2512
Publikováno v:
Methods in Molecular Biology ISBN: 9781493996452
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f562d10a76c01752b5530873d89bba12
https://doi.org/10.1007/978-1-4939-9646-9_15
https://doi.org/10.1007/978-1-4939-9646-9_15
Autor:
Skirmantas Kriaucionis, Edith Heard, Neil Brockdorff, Daniella Moralli, Greta Pintacuda, Ye Zhan, Michal R. Gdula, Tatyana B. Nesterova, Wolf Reik, Catherine M. Green, Felix Krueger, Job Dekker, Hakan Ozadam, Michael McClellan, Jonathan Godwin
The inactive X chromosome (Xi) in female mammals adopts an atypical higher-order chromatin structure, manifested as a global loss of local topologically associated domains (TADs), and formation of two mega-domains. In this study we demonstrate that t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::35239ae794101056ac1a11b1d359ab32
Autor:
Krzysztof Poterlowicz, Andrey A. Sharov, Vladimir A. Botchkarev, Michael Y. Fessing, I. Malashchuk, Andrei N. Mardaryev, Michal R. Gdula, Joanne L. Yarker, Brian R. Lajoie, Terumi Kohwi-Shigematsu
Publikováno v:
PLoS genetics, vol 13, iss 9
PLoS Genetics, Vol 13, Iss 9, p e1006966 (2017)
PLoS Genetics
PLoS Genetics, Vol 13, Iss 9, p e1006966 (2017)
PLoS Genetics
Mammalian genomes contain several dozens of large (>0.5 Mbp) lineage-specific gene loci harbouring functionally related genes. However, spatial chromatin folding, organization of the enhancer-promoter networks and their relevance to Topologically Ass
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a3f03a77ad4d757f6ebbbdb83a11ce7
https://escholarship.org/uc/item/9pv8g12z
https://escholarship.org/uc/item/9pv8g12z
Autor:
Vladimir A. Botchkarev, Yonghong Peng, Michael Y. Fessing, Michal R. Gdula, Krzysztof Poterlowicz, Andrei N. Mardaryev, Andrey A. Sharov
Publikováno v:
Journal of Investigative Dermatology. 133(9):2191-2201
The nucleus of epidermal keratinocytes (KCs) is a complex and highly compartmentalized organelle, whose structure is markedly changed during terminal differentiation and transition of the genome from a transcriptionally active state seen in the basal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b25e15c07b9b4e37d09696b12a65af6
Autor:
O. Zlobinskaya, Gunnar Brunborg, Krzysztof Poterlowicz, Roger W. L. Godschalk, Diana Anderson, Michal R. Gdula, Eleni Fthenou, Jos C. S. Kleinjans, Adolf Baumgartner, Thomas E. Schmid, Julian Laubenthal, S. J. Hepworth, Maria Keramarou, Frederik-Jan van Schooten
Publikováno v:
Faseb Journal, 26(10), 3946-3956. FASEB
The relevance of preconceptional and prenatal toxicant exposures for genomic stability in offspring is difficult to analyze in human populations, because gestational exposures usually cannot be separated from preconceptional exposures. To analyze the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::948e21d4224221836fa346922217c9d0
https://doi.org/10.1096/fj.11-201194
https://doi.org/10.1096/fj.11-201194
Autor:
Anna Kostrzak, Piotr Bociąg, Halina Otta, Sławomir Samardakiewicz, Piotr Wójcik, Andrzej Plucienniczak, Michal R. Gdula, Olga Fedorowicz-Strońska, Bogdan Wolko, Tomasz Pniewski, Jacek Wojciechowicz, Józef Kapusta
Publikováno v:
Journal of Applied Genetics
Efficient immunization against hepatitis B virus (HBV) and other pathogens with plant-based oral vaccines requires appropriate plant expressors and the optimization of vaccine compositions and administration protocols. Previous immunization studies w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ca041cea3d9bf92e26d8e6464b8c39eb
http://europepmc.org/articles/PMC3088802
http://europepmc.org/articles/PMC3088802
Autor:
I. Malashchuk, Joanne L. Yarker, Michal R. Gdula, Vladimir A. Botchkarev, Terumi Kohwi-Shigematsu, Michael Y. Fessing, Andrey A. Sharov, Krzysztof Poterlowicz, Andrei N. Mardaryev
Publikováno v:
Journal of Investigative Dermatology. 137:S208
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b7ad75c66d4be2e0ce5f0cdb114889c3
https://doi.org/10.1016/j.jid.2017.07.401
https://doi.org/10.1016/j.jid.2017.07.401
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 1044
DNA damage through endogenous and environmental toxicants is a constant threat to both a human's ability to pass on intact genetic information to its offspring as well as somatic cells for their own survival. To counter these threats posed by DNA dam
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::e94b0b75c5b6f7301901aee6b0a6d0c7
https://pubmed.ncbi.nlm.nih.gov/23896884
https://pubmed.ncbi.nlm.nih.gov/23896884