Zobrazeno 1 - 10
of 47
pro vyhledávání: '"Michal R Tomaszewski"'
Autor:
Michal R. Tomaszewski, Alexander L. Sukstanskii, Hyking Haley, Xiangjun Meng, Corin O. Miller, Dmitriy A. Yablonskiy
Publikováno v:
NeuroImage, Vol 298, Iss , Pp 120794- (2024)
Robust methods are needed for preclinical evaluation of novel Alzheimer Disease (AD) therapies to accelerate drug discovery. Quantitative Gradient Recalled Echo (qGRE) MRI has shown promise to provide insight into neurodegeneration in AD prior to atr
Externí odkaz:
https://doaj.org/article/aef6c483f9084e05bdd928adfab0bc1f
Autor:
Michal R. Tomaszewski, Xiangjun Meng, Hyking D. Haley, Charles M. Harrell, Terrence P. Mcdonald, Corin O. Miller, Sean M. Smith
Publikováno v:
Journal of Lipid Research, Vol 64, Iss 8, Pp 100408- (2023)
Weight gain is a common harmful side effect of atypical antipsychotics used for schizophrenia treatment. Conversely, treatment with the novel phosphodiesterase-10A (PDE10A) inhibitor MK-8189 in clinical trials led to significant weight reduction, esp
Externí odkaz:
https://doaj.org/article/75aa8f1b2779458bb44d7d39037b5d33
Autor:
Michal R. Tomaszewski, Shuxuan Fan, Alberto Garcia, Jin Qi, Youngchul Kim, Robert A. Gatenby, Matthew B. Schabath, William D. Tap, Denise K. Reinke, Rikesh J. Makanji, Damon R. Reed, Robert J. Gillies
Publikováno v:
Tomography, Vol 8, Iss 1, Pp 341-355 (2022)
Purpose: Success of clinical trials increasingly relies on effective selection of the target patient populations. We hypothesize that computational analysis of pre-accrual imaging data can be used for patient enrichment to better identify patients wh
Externí odkaz:
https://doaj.org/article/b7bfcc234f824a8f824df183331d4c45
Autor:
Mariyah Pressley, Jill A. Gallaher, Joel S. Brown, Michal R. Tomaszewski, Punit Borad, Mehdi Damaghi, Robert J. Gillies, Christopher J. Whelan
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-14 (2021)
Abstract Tumors experience temporal and spatial fluctuations in oxygenation. Hypoxia inducible transcription factors (HIF-α) respond to low levels of oxygen and induce re-supply oxygen. HIF-α stabilization is typically facultative, induced by hypox
Externí odkaz:
https://doaj.org/article/80fe1800dde0464a95b640975ccb6ff5
Autor:
Thierry L. Lefebvre, Emma Brown, Lina Hacker, Thomas Else, Mariam-Eleni Oraiopoulou, Michal R. Tomaszewski, Rajesh Jena, Sarah E. Bohndiek
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
Radiotherapy is recognized globally as a mainstay of treatment in most solid tumors and is essential in both curative and palliative settings. Ionizing radiation is frequently combined with surgery, either preoperatively or postoperatively, and with
Externí odkaz:
https://doaj.org/article/40c9b9bf4c6f4baa815e1f3c2549753f
Autor:
Kevin M. Brindle, Robert W. Wilkinson, Sarah E. Bohndiek, Richard C.A. Sainson, David Tice, Stefanie R. Mullins, Sarah McGuire, De-En Hu, Susana Ros, André A. Neves, Michal R. Tomaszewski, Bangwen Xie
Supplementary videos. Representative reconstructed 3D rendering of a Colo205 tumor 3 h after injection of 0.2 µmole/kg of C2Am-750. Signals from C2Am-750, oxygenated hemoglobin (HbO2), deoxygenated hemoglobin (Hb) are shown in green, red and blue re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::33b293660af54350dae220ee09a01c2b
https://doi.org/10.1158/1078-0432.22463276.v1
https://doi.org/10.1158/1078-0432.22463276.v1
Autor:
Kevin M. Brindle, Robert W. Wilkinson, Sarah E. Bohndiek, Richard C.A. Sainson, David Tice, Stefanie R. Mullins, Sarah McGuire, De-En Hu, Susana Ros, André A. Neves, Michal R. Tomaszewski, Bangwen Xie
Supplementary figures 1 - 4. Caption for video file.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a8b461b7c2a039461eaf997b9ce45034
https://doi.org/10.1158/1078-0432.22463279.v1
https://doi.org/10.1158/1078-0432.22463279.v1
Autor:
Kevin M. Brindle, Robert W. Wilkinson, Sarah E. Bohndiek, Richard C.A. Sainson, David Tice, Stefanie R. Mullins, Sarah McGuire, De-En Hu, Susana Ros, André A. Neves, Michal R. Tomaszewski, Bangwen Xie
Purpose: The development of new treatments and their deployment in the clinic may be assisted by imaging methods that allow an early assessment of treatment response in individual patients. The C2A domain of Synaptotagmin-I (C2Am), which binds to the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::03869d7447f0a5db80e579a7bc991957
https://doi.org/10.1158/1078-0432.c.6525359.v1
https://doi.org/10.1158/1078-0432.c.6525359.v1
Autor:
Sarah E. Bohndiek, Rosa M. Sainz, Dominique-Laurent Couturier, Lina Hacker, Laura Ansel-Bollepalli, Emma Brown, Monika A. Golinska, Michal R. Tomaszewski, Isabel Quiros-Gonzalez
Supplementary Data from Photoacoustic Tomography Detects Response and Resistance to Bevacizumab in Breast Cancer Mouse Models
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0bbad5b73d645b571d151e92a424a561
https://doi.org/10.1158/0008-5472.22430002
https://doi.org/10.1158/0008-5472.22430002
Autor:
Sarah E. Bohndiek, Rosa M. Sainz, Dominique-Laurent Couturier, Lina Hacker, Laura Ansel-Bollepalli, Emma Brown, Monika A. Golinska, Michal R. Tomaszewski, Isabel Quiros-Gonzalez
Angiogenesis is an established prognostic factor in advanced breast cancer, yet response to antiangiogenic therapies in this disease remains highly variable. Noninvasive imaging biomarkers could help identify patients that will benefit from antiangio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::307c7546f69ad4eac36f41ed58e3ad4b
https://doi.org/10.1158/0008-5472.c.6513511
https://doi.org/10.1158/0008-5472.c.6513511