Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Michal Pokusa"'
Autor:
Andrea Evinova, Beata Cizmarova, Michal Pokusa, Renata Pecova, Martin Pec, Katarina Dibdiaková
Publikováno v:
Acta Medica Martiniana, Vol 24, Iss 1, Pp 42-48 (2024)
Various types of cancer exhibit distinct sensitivities to anticancer drugs, reflecting their unique developmental pathways. Exploiting mitochondrial dysfunction in cancer cells presents novel therapeutic opportunities. In recent years, advancements h
Externí odkaz:
https://doaj.org/article/4ffd8ee93cd24fb381c77e6a33ecc56f
Autor:
Dominika Hajduchova, Stanislava Suroviakova, Sandra Mersakova, Dusan Brany, Romana Zahumenska, Martin Rehak, Henrieta Skovierova, Slavomíra Nováková, Vladimir Nosal, Juraj Marcinek, Michal Kalman, Martin Jozef Pec, Mariana Brozmanova, Jana Melegova, Stefan Juhas, Jana Juhasova, Hana Studenovska, Barbora Mitruskova, Michal Pokusa, Marek Samec, Matej Samos, Andreas Nicodemou, Lubos Danisovic, Zuzana Dankova, Egon Kurca, Katarina Lexova Kolejakova, Jan Chandoga, Lukas Plank, Erika Halasova, Renata Pecova, Jan Strnadel
Publikováno v:
Stem Cell Research, Vol 71, Iss , Pp 103187- (2023)
Here, we present newly derived in vitro model for modeling Duchenne muscular dystrophy. Our new cell line was derived by reprogramming of peripheral blood mononuclear cells (isolated from blood from pediatric patient) with Sendai virus encoding Yaman
Externí odkaz:
https://doaj.org/article/b840dd393efe463882ba1a573dacb2ac
Quantification of Iron Release from Native Ferritin and Magnetoferritin Induced by Vitamins B2 and C
Autor:
Oliver Strbak, Lucia Balejcikova, Martina Kmetova, Jan Gombos, Alzbeta Trancikova, Michal Pokusa, Peter Kopcansky
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 17, p 6332 (2020)
Various pathological processes in humans are associated with biogenic iron accumulation and the mineralization of iron oxide nanoparticles, especially magnetite. Ferritin has been proposed as a precursor to pathological magnetite mineralization. This
Externí odkaz:
https://doaj.org/article/c3fac8da71f54e90b1bca401e949f76c
Autor:
Terezia Okajcekova, Jan Strnadel, Michal Pokusa, Romana Zahumenska, Maria Janickova, Erika Halasova, Henrieta Skovierova
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 7, p 2280 (2020)
Dental pulp stem cells (DPSCs) have excellent proliferative properties, mineralization potential and can be easily obtained from third molar teeth. Recently, many studies have focused on isolation and differentiation of DPSCs. In our study, we focuse
Externí odkaz:
https://doaj.org/article/cdd023fb398846a287e3184397172548
Autor:
Katarina Ziakova, Maria Kovalska, Ivana Pilchova, Katarina Dibdiakova, Michal Pokusa, Dagmar Kalenska, Peter Racay
A brief period of transient global brain ischemia leads to a selective ischemic neurodegeneration associated with death of hippocampal CA1 pyramidal neurons days after reperfusion. The mechanism of such selective and delayed neurodegeneration is stil
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e063b069976e68b64149d7a7ac1d4544
https://doi.org/10.21203/rs.3.rs-2174277/v1
https://doi.org/10.21203/rs.3.rs-2174277/v1
Autor:
Dominika Hajduchova, Roman Holic, Peter Gajdos, Milan Certik, Erika Halasova, Renata Pecova, Michal Pokusa
Publikováno v:
General physiology and biophysics. 41(6)
Events associated with the progression of Parkinson´s disease (PD) are closely related to biomembrane dysfunction. The specific role of membrane composition in the conformational stability of alpha synuclein (αS) has already been well documented. A
Publikováno v:
Physiol Res
Numerous pathological changes of subcellular structures are characteristic hallmarks of neurodegeneration. The main research has focused to mitochondria, endoplasmic reticulum, Golgi apparatus, lysosomal networks as well as microtubular system of the
Autor:
Michal Pokusa, A. Kráľová Trančíková
Publikováno v:
Physiological Research. :S673-S683
Parkinson's disease (PD) is currently the second most common neurodegenerative disorder in the world. Major features of cell pathology of the disease include the presence of cytoplasmic inclusions called Lewy bodies, which are composed of aggregated
Autor:
Ivan Kocan, Adriana Kompanikova, Zuzana Kolková, Dana Dvorská, Dusan Loderer, M Sarlinova, Vladimir Nosal, Veronika Holubekova, Martina Hrnciarova, Dusan Brany, Jana Kompanikova, Michal Pokusa, Jan Strnadel, Maria Skerenova, Sandra Mersakova, M Petras, Nina Kotlebova, Andrea Stanclova, Katarína Janíková, V. Sadlonova, Zuzana Dankova, M Antosova, Marek Samec, Dusan Krkoska, Ivana Kasubova, Vincent Lucansky, Dalibor Murgas, Anton Dzian, Andrea Calkovska, Erika Halasova, Elena Novakova
Publikováno v:
International Journal of Environmental Research and Public Health
International Journal of Environmental Research and Public Health, Vol 18, Iss 7037, p 7037 (2021)
Volume 18
Issue 13
International Journal of Environmental Research and Public Health, Vol 18, Iss 7037, p 7037 (2021)
Volume 18
Issue 13
The global pandemic of coronavirus disease 2019 (COVID-19) caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is having a tremendous impact on the global economy, health care systems and the lives of almost all people in the w
Autor:
Michal Pokusa, Dusan Dobrota, Alžbeta Kráľová Trančíková, Eva Baranovicova, Radovan Murín, Zuzana Majerčíková, Peter Bystrický, Eduard Gondáš
Publikováno v:
General physiology and biophysics. 40(2)
Pyruvate carboxylase (PC) is an enzyme catalyzing the conversion of pyruvate to oxaloacetate, which possesses anaplerotic role in cellular metabolism. The expression of PC was confirmed in cells of several cancer types, in which it ensures several ce