Výsledky vyhledávání - "Michal Pawlik"

Gastroprotective action of orexin-A against stress-induced gastric damage is mediated by endogenous prostaglandins, sensory afferent neuropeptides and nitric oxide

Autor: Grzegorz Burnat, Michal Pawlik, Atsuzakau Kuwahara, Tomasz Brzozowski, Wieslaw W. Pawlik, Władysław Bielański, Stanislaw J. Konturek, Ikuo Kato, Danuta Drozdowicz, Zbigniew Sliwowski, Robert Pajdo, Peter C. Konturek

Publikováno v: Regulatory Peptides. 148:6-20

Orexin-A, identified in the neurons and endocrine cells in the gut, has been implicated in control of food intake and sleep behavior but little is known about its influence on gastric secretion and mucosal integrity. The effects of orexin-A on gastri

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::89e4443e17feed6d2a5ae9fc4d89e929
https://doi.org/10.1016/j.regpep.2008.02.003

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Gastric secretion, proinflammatory cytokines and epidermal growth factor (EGF) in the delayed healing of lingual and gastric ulcerations by testosterone

Autor: Stanislaw J. Konturek, M. Schwarz, Thomas Brzozowski, P C Konturek, Danuta Drozdowicz, Zbigniew Sliwowski, Anna Machowska, Wieslaw W. Pawlik, J. Stachura, Robert Pajdo, Michal Pawlik, Alexandra Szlachcic

Publikováno v: Inflammopharmacology. 16:40-47

Hormonal fluctuations are known to predispose ulceration of the upper gastrointestinal tract, but to date no comparative study of their effects on the healing of pre-existing ulcers in the oral cavity and stomach has been made. We studied the effects

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7710974abd424dd495f6d4d8b752d3a0
https://doi.org/10.1007/s10787-007-1600-6

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Role of central and peripheral ghrelin in the mechanism of gastric mucosal defence

Autor: Danuta Drozdowicz, Zbigniew Sliwowski, Peter C. Konturek, Michal Pawlik, Eckhart G. Hahn, Tomasz Brzozowski, Stanislaw J. Konturek, Wieslaw W. Pawlik

Publikováno v: InflammoPharmacology. 13:45-62

Ghrelin, identified in the gastric mucosa, has been involved in the control of food intake and growth hormone (GH) release, but whether this hormone influences the gastric secretion and gastric mucosal integrity has been little elucidated. We compare

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dcc1773df591ec1c9e4c14e69d189398
https://doi.org/10.1163/156856005774423971

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Involvement of nitric oxide (NO) in the mechanism of gastric preconditioning induced by short ischemia

Autor: Agata Ptak, Robert Pajdo, Tomasz Brzozowski, Stanislaw J. Konturek, Michal Pawlik, Eckhart G. Hahn, Peter C. Konturek, Danuta Drozdowicz

Publikováno v: InflammoPharmacology. 10:449-460

Gastric mucosa subjected to repeated brief episodes of ischemia exhibits an increased resistance to damage caused by a subsequent prolonged ischemic insult and this is called gastric preconditioning. In this study, L-NNA, a non-selective NO-synthase

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::3703d7b45a8f6c0be449c0ce52a8ec32
https://doi.org/10.1163/156856002321544918

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Role of prostaglandins, nitric oxide, sensory nerves and gastrin in acceleration of ulcer healing by melatonin and its precursor, L-tryptophan

Autor: Iwona Brzozowska, Eckhart G. Hahn, Peter C. Konturek, Slawomir Kwiecien, Robert Pajdo, Stanislaw J. Konturek, Tomasz Brzozowski, Danuta Drozdowicz, Michal Pawlik, Agata Ptak

Publikováno v: Journal of Pineal Research. 32:149-162

Melatonin, a major hormone of pineal gland, was recently shown to attenuate acute gastric lesions induced by strong irritants because of the scavenging of free radicals but its role in ulcer healing has been little investigated. In this study we comp

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::1fbeca55e6544f26b4028adc6edd522f
https://doi.org/10.1034/j.1600-079x.2002.1o811.x

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Ischemic preconditioning, the most effective gastroprotective intervention: involvement of prostaglandins, nitric oxide, adenosine and sensory nerves

Autor: Stanislaw J. Konturek, Peter C. Konturek, Slawomir Kwiecien, Eckhart G. Hahn, Danuta Drozdowicz, Zbigniew Sliwowski, Tomasz Brzozowski, Michal Pawlik, Robert Pajdo, Agata Ptak

Publikováno v: European Journal of Pharmacology. 427:263-276

Various organs, including heart, kidneys, liver or brain, respond to brief exposures to ischemia with an increased resistance to severe ischemia/reperfusion and this phenomenon is called "preconditioning". No study so far has been undertaken to check

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1fd3f9ed4d305beb942e9acf4a7f83d9
https://doi.org/10.1016/s0014-2999(01)01246-8

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Involvement of gastrin in gastric secretory and protective actions of N-alpha-methyl histamine

Autor: Stanislaw J. Konturek, Tomasz Brzozowski, Michal Pawlik, Eckhart G. Hahn, Agata Ptak, Danuta Drozdowicz, Peter C. Konturek, Robert Pajdo, Slawomir Kwiecien

Publikováno v: Journal of Physiology-Paris. 95:89-98

N alpha-methylhistamine (N alpha-MH) is one of an unusual metabolite of histamine that was found in Helicobacter pylori-infected stomachs and is believed to interact with specific histamine H(1), H(2) and H(3)-receptors to stimulate gastric acid secr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4532bbcf4988a6778ad8ea197d27590a
https://doi.org/10.1016/s0928-4257(01)00013-4

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Role of angiotensin-(1-7) in gastroprotection against stress-induced ulcerogenesis. The involvement of mas receptor, nitric oxide, prostaglandins, and sensory neuropeptides

Autor: Ryszard Korbut, Tomasz Brzozowski, Rafał Olszanecki, Katarzyna Jasnos, Agata Ptak-Belowska, Gracjana Krzysiek-Maczka, Michal Pawlik, Marcin Magierowski, Slawomir Kwiecien

Publikováno v: The Journal of pharmacology and experimental therapeutics. 347(3)

Angiotensin-(1-7) [Ang-(1-7)] is a major vasoactive metabolite of angiotensin I (Ang I), both being important components of the renin-angiotensin system (RAS). Ang-(1-7) acting via Mas receptor was documented in kidneys, heart, brain, and gastrointes

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::14ed82abcdbaf5b1d47c379ebe239bd2
https://pubmed.ncbi.nlm.nih.gov/25934764

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Esophagoprotection mediated by exogenous and endogenous melatonin in an experimental model of reflux esophagitis

Autor: Russel J. Reiter, Iwona Brzozowska, Michal Pawlik, Slawomir Kwiecien, Tomasz Brzozowski, Aneta Targosz, Stanislaw J. Konturek, Peter C. Konturek, Joanna Kania, Thomas Hess

Reflux esophagitis is a common clinical entity in western countries with approximately 30% of the population experiencing the symptoms at least once every month. The imbalance between the protective and aggressive factors leads to inflammation and da

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a71f232283974adb2ed6df3141c84b25
https://ruj.uj.edu.pl/xmlui/handle/item/118667

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