Zobrazeno 1 - 10
of 71
pro vyhledávání: '"Michal Novotny"'
Autor:
Michal Novotny, Jan Bulla, Daniela Hubl, Sebastian Karl Maximilian Fischer, Martin Grosshans, Andreas Gutzeit, Oliver Bilke-Hentsch, Erich Seifritz, Jochen Mutschler
Publikováno v:
Frontiers in Public Health, Vol 11 (2024)
BackgroundPregabalin is a gamma-aminobutyric acid (GABA) analog that was approved in the EU in 2004 for the treatment of neuropathic pain, generalized anxiety disorder and epilepsy. Since its introduction, pregabalin abuse and misuse has increased si
Externí odkaz:
https://doaj.org/article/a26f53d231c0402b8f77979f978d607d
Autor:
Martin Valis, Alzbeta Dlabkova, Jakub Hort, Francesco Angelucci, Jaroslav Pejchal, Kamil Kuca, Zbysek Pavelek, Jana Zdarova Karasova, Michal Novotny
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 165, Iss , Pp 115226- (2023)
Externí odkaz:
https://doaj.org/article/e9d9c5fb4f944a3ab5793b47851d58ee
Autor:
Dominik Skrabal, Jan Rusz, Michal Novotny, Karel Sonka, Evzen Ruzicka, Petr Dusek, Tereza Tykalova
Publikováno v:
npj Parkinson's Disease, Vol 8, Iss 1, Pp 1-7 (2022)
Abstract Imprecise vowels represent a common deficit associated with hypokinetic dysarthria resulting from a reduced articulatory range of motion in Parkinson’s disease (PD). It is not yet unknown whether the vowel articulation impairment is alread
Externí odkaz:
https://doaj.org/article/e7fecb6a1bd6485f936955322ae4a94b
Publikováno v:
npj Digital Medicine, Vol 5, Iss 1, Pp 1-8 (2022)
Abstract Even though hypomimia is a hallmark of Parkinson’s disease (PD), objective and easily interpretable tools to capture the disruption of spontaneous and deliberate facial movements are lacking. This study aimed to develop a fully automatic v
Externí odkaz:
https://doaj.org/article/4e9119db6ce9426ca6e94d9491c7be49
Autor:
Martin Valis, Alzbeta Dlabkova, Jakub Hort, Francesco Angelucci, Jaroslav Pejchal, Kamil Kuca, Zbysek Pavelek, Jana Zdarova Karasova, Michal Novotny
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 159, Iss , Pp 114223- (2023)
Background: The acetylcholinesterase inhibitor donepezil is administered as a treatment for Alzheimer's disease (AD). However, the appropriate donepezil dosage is still a matter of debate. Methods: Forty AD patients receiving 10 mg/day of donepezil w
Externí odkaz:
https://doaj.org/article/9493af4d107e474493dfe188b7444fcc
Publikováno v:
npj Parkinson's Disease, Vol 8, Iss 1, Pp 1-6 (2022)
Abstract The effect of dopaminergic medication on speech has rarely been examined in early-stage Parkinson’s disease (PD) and the respective literature is inconclusive and limited by inappropriate design with lack of PD control group. The study aim
Externí odkaz:
https://doaj.org/article/24840ed693974fc4aa0ba2bf13a4dc84
Autor:
Zbysek Pavelek, Ondrej Soucek, Jan Krejsek, Ilona Sejkorova, Oldrich Vysata, Blanka Klimová, Francesco Angelucci, Pavel Stourac, Martin Valis, Marek Peterka, Lukáš Sobisek, Michal Novotny
Publikováno v:
Journal of Immunology Research, Vol 2023 (2023)
Background. The QuantiFERON®-Monitor (QFM) is an assay that measures interferon-γ production and was developed to provide an objective marker of complex immune response. In this study, we evaluated the use of the QFM test in patients with two forms
Externí odkaz:
https://doaj.org/article/681588e3d4a84d559d0b5dd4548066b2
Autor:
Patrik Oleksak, Michal Novotny, Jiri Patocka, Eugenie Nepovimova, Jakub Hort, Jan Pavlik, Blanka Klimova, Martin Valis, Kamil Kuca
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 16, p 8908 (2021)
At present, Alzheimer’s disease (AD) and related dementias cannot be cured. Therefore, scientists all over the world are trying to find a new approach to prolong an active life of patients with initial dementia. Both pharmacological and non-pharmac
Externí odkaz:
https://doaj.org/article/3ba7a53834fd46ae916f5fc9086860f4
Publikováno v:
Nutrients, Vol 13, Iss 6, p 2067 (2021)
At present, due to the demographic changes and the rise of senior population worldwide, there is effort to prolong an active life of these people by both pharmacological and non-pharmacological strategies. The purpose of this article is, on the basis
Externí odkaz:
https://doaj.org/article/2dbf83dc7ecd4704bdf0cfdff451d6b6
Publikováno v:
Frontiers in Neurology, Vol 9 (2019)
The purpose of this review study is to reveal a potential threat of one type of such widely used and freely distributed drugs, which are proton pump inhibitors that might be the cause of the onset of both dementia and depression. The authors performe
Externí odkaz:
https://doaj.org/article/5459987af0df4e9e9e1f5bfb172a7917