Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Michal Margalith"'
Autor:
Denise L. Doolan, Robert A. Gramzinski, Richard C. Hedstrom, Joao C. Aguiar, Ruobing Wang, Martha Sedegah, Stephen L. Hoffman, Walter R. Weiss, Anita Malik, Peter Hobart, Jon Norman, Michal Margalith
Publikováno v:
Vaccine. 15:842-845
Data generated in the Plasmodium yoelii rodent model indicated that plasmid DNA vaccines encoding the P. yoelii circumsporozoite protein (PyCSP) or 17 kDa hepatocyte erythrocyte protein (PyHEP17) were potent inducers of protective CD8+ T cell respons
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::58ab7cf6d81c483eb369181b7947ff35
https://doi.org/10.1016/s0264-410x(96)00273-3
https://doi.org/10.1016/s0264-410x(96)00273-3
Autor:
Marston Manthorpe, Jiin Felgner, Jukka Hartikka, Francine Cornefert-Jensen, Ann Rundell, Michal Margalith, Varavani Dwarki
Publikováno v:
Scopus-Elsevier
Direct injection of nonviral, covalently closed circular plasmid DNA into muscle results in expression of the DNA in myofiber cells. We have examined the expression of firefly luciferase DNA constructs injected into adult murine skeletal muscle. Cons
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f7c308e259b314b2ace693d2b32dddcc
https://doi.org/10.1089/hum.1993.4.4-419
https://doi.org/10.1089/hum.1993.4.4-419
Autor:
Michal Margalith, Kai M. Wilhelm, David M. Koelle, William J. Muller, David Kaslow, Benjamin Byrd, Lichun Dong, Adrian Vilalta, Christopher L. McClurkan, John Sidney, Chao Liu, Alessandro Sette
Publikováno v:
The Journal of general virology. 90(Pt 5)
Cytotoxic T cells are important in controlling herpes simplex virus type 2 (HSV-2) reactivation and peripheral lesion resolution. Humans latently infected with HSV-2 have cytotoxic T cells directed against epitopes present in tegument proteins. Studi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::457d19ecf1601fde750fab5a361fe35c
https://pubmed.ncbi.nlm.nih.gov/19264627
https://pubmed.ncbi.nlm.nih.gov/19264627
Autor:
Michal Margalith, Peter Hobart, Nicanor Obaldia, Martha Sedegah, Stephen L. Hoffman, Ruobing Wang, Yupin Charoenvit, RN Rossan, Denise L. Doolan, Dorina C. Maris, Robert A. Gramzinski
Publikováno v:
Vaccine. 15:913-915
In preparation for the development of DNA vaccines designed to produce protective antibodies against Plasmodium falciparum antigens (Ag), we conducted studies to optimize antibody responses in Aotus monkeys after immunization with the P. yoelli circu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d64d0cb5b9a5b0d14c070f101476190b
https://doi.org/10.1016/s0264-410x(96)00270-8
https://doi.org/10.1016/s0264-410x(96)00270-8
Autor:
Denise L. Doolan, John A. Tine, Richard C. Hedstrom, Yupin Charoenvit, Joao C. Aguiar, Malcolm J. Gardner, Stephen L. Hoffman, Michal Margalith, John B. Sacci, R. Wang, Peter Hobart, Martha Sedegah, Anita Kumar
Publikováno v:
Europe PubMed Central
DNA vaccine plasmids were constructed that encoded four pre-erythrocytic antigens from the human malaria parasite Plasmodium falciparum: circumsporozoite protein (PfCSP); sporozoite surface protein 2 (PfSSP2); carboxyl terminus of liver stage antigen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9bb5170b38eaf0a18dbbf19488861550
https://pubmed.ncbi.nlm.nih.gov/9854139
https://pubmed.ncbi.nlm.nih.gov/9854139
Autor:
Ruobing Wang, Kevin M. Coonan, Jon Norman, Walter R. Weiss, Thong P. Le, Stephen L. Hoffman, Martha Sedegah, Trevor R. Jones, Yupin Charoenvit, Jennifer Ng, Richard C. Hedstrom, Michal Margalith, Denise L. Doolan, Charles de Taisne, Peter Hobart
Publikováno v:
Science (New York, N.Y.). 282(5388)
CD8+cytotoxic T lymphocytes (CTLs) are critical for protection against intracellular pathogens but often have been difficult to induce by subunit vaccines in animals. DNA vaccines elicit protective CD8+T cell responses. Malaria-naı̈ve volunteers wh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1eced73ef3d0c8918f461489770865cc
https://pubmed.ncbi.nlm.nih.gov/9774275
https://pubmed.ncbi.nlm.nih.gov/9774275
Autor:
Stephen L. Hoffman, Malcolm J. Gardner, Richard C. Hedstrom, Denise L. Doolan, H. Wang, Robert A. Gramzinski, Michal Margalith, Peter Hobart, Martha Sedegah
Publikováno v:
Current Topics in Microbiology and Immunology ISBN: 9783642804779
During the twentieth century, the primary approach to malaria prevention has been to interfere with transmission of the parasite between the infected mosquito and the human host using physical barriers, insecticides and prophylactic drugs. Despite th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6c9374a63bee9ee6e0997ca41f901ad6
https://doi.org/10.1007/978-3-642-80475-5_3
https://doi.org/10.1007/978-3-642-80475-5_3
Autor:
Richard C. Hedstrom, Denise L. Doolan, Ruobing Wang, Malcolm J. Gardner, Anita Kumar, Martha Sedegah, Robert A. Gramzinski, John B. Sacci, Yupin Charoenvit, Walter R. Weiss, Michal Margalith, Jon A. Norman, Peter Hobart, Stephen L. Hoffman
Publikováno v:
Gene Vaccination: Theory and Practice ISBN: 9783642468698
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b2801c69f175072751cd6de5ddf4e49a
https://doi.org/10.1007/978-3-642-46867-4_3
https://doi.org/10.1007/978-3-642-46867-4_3
Autor:
Malcolm J. Gardner, Richard C. Hedstrom, Martha Sedegah, Robert A. Gramzinski, Michal Margalith, Denise L. Doolan, Stephen L. Hoffman, Peter Hobart, Helen Heng Wang, Joao C. Aguiar, Ruobing Wang
Publikováno v:
Journal of pharmaceutical sciences. 85(12)
Since the first demonstration of the technology a few years ago, DNA vaccines have emerged as a promising method of vaccination. In a variety of experimental systems, DNA vaccines have been shown not only to induce potent immune responses, but also t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4639b78422661adf7275fd84e80f0048
https://pubmed.ncbi.nlm.nih.gov/8961142
https://pubmed.ncbi.nlm.nih.gov/8961142
Autor:
Peter Hobart, Michal Margalith, Hugh B. Black, Eric C. Svensson, Sandeep K. Tripathy, Eugene Goldwasser, Jeffrey M. Leiden
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 93(20)
Erythropoietin (Epo)-responsive anemia is a common and debilitating complication of chronic renal failure and human immunodeficiency virus infection. Current therapy for this condition involves repeated intravenous or subcutaneous injections of recom
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d436b2a2b6d5356a0234cbf61eba761c
https://pubmed.ncbi.nlm.nih.gov/8855275
https://pubmed.ncbi.nlm.nih.gov/8855275