Zobrazeno 1 - 10
of 172
pro vyhledávání: '"Michal Lebl"'
Autor:
Mikhail Makarov, Alma C. Sanchez Rocha, Robin Krystufek, Ivan Cherepashuk, Volha Dzmitruk, Tatsiana Charnavets, Anneliese M. Faustino, Michal Lebl, Kosuke Fujishima, Stephen D. Fried, Klara Hlouchova
Publikováno v:
Journal of the American Chemical Society. 145:5320-5329
Whereas modern proteins rely on a quasi-universal repertoire of 20 canonical amino acids (AAs), numerous lines of evidence suggest that ancient proteins relied on a limited alphabet of 10 ‘early’ AAs, and that the 10 ‘late’ AAs were products
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c2ca8cb37b64e3946b9527babfc6bab5
https://doi.org/10.1021/jacs.2c12987
https://doi.org/10.1021/jacs.2c12987
Publikováno v:
Sensors and Actuators A: Physical. 169:250-255
a b s t r a c t This paper presents a radial frit geometry electroosmotic pump with a soft, semi-permeable gas venting membrane top. Radial pumps exhibit more than three times the average open flow rate per applied voltage and four times the average
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a601fdcf566651b824de62cfad0caedd
https://doi.org/10.1016/j.sna.2011.05.013
https://doi.org/10.1016/j.sna.2011.05.013
Autor:
Michal Lebl
Publikováno v:
Amino Acids, Peptides and Proteins in Organic Chemistry: Protection Reactions, Medicinal Chemistry, Combinatorial Synthesis, Volume 4
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dd983ab90ce0a1f214bf0937bc6d444d
https://doi.org/10.1002/9783527631827.ch12
https://doi.org/10.1002/9783527631827.ch12
Publikováno v:
International Journal of Peptide and Protein Research. 40:148-151
Four diastereomeric analogs of oxytocin containing substituted phenylalanine in position 2 were synthesized. This modified phenylalanine side chain contained one methyl group attached to the beta-carbon and the second one at the 2' position of the ar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ca719ef870569a5927324ea14b4151b
https://doi.org/10.1111/j.1399-3011.1992.tb01463.x
https://doi.org/10.1111/j.1399-3011.1992.tb01463.x
Publikováno v:
International Journal of Peptide and Protein Research. 43:31-38
The extent of transfer of the Pmc protecting group from the guanidino group of arginine to the side chain of tryptophan depends on the spacial distance of these side chains. When these two amino acids are separated by one amino acid, the transfer of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::31af8e9a6415caba02d7eca18bbbebbe
https://doi.org/10.1111/j.1399-3011.1994.tb00373.x
https://doi.org/10.1111/j.1399-3011.1994.tb00373.x
Publikováno v:
International Journal of Peptide and Protein Research. 29:40-45
The downfield shift of the tyrosyl proton resonances and an increased chemical shift difference between the resonances for the 2',6' and 3',5' hydrogens in a series of deamino-oxytocin analogs modified in the disulfide bridge provide evidence for aro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c56769bd49199187309dd1eb3f7c5594
https://doi.org/10.1111/j.1399-3011.1987.tb02227.x
https://doi.org/10.1111/j.1399-3011.1987.tb02227.x
Autor:
Piotr Cieplak, Roxane Desjardins, Robert Day, Boris I. Ratnikov, Alex Y. Strongin, Michal Lebl, Eok Soo Oh, Sergey A. Shiryaev, Jeffrey W. Smith, Robert C. Liddington, Albert G. Remacle, Anupama Srinivasan, Ge Wei, Amelie Parent
Publikováno v:
Journal of Biological Chemistry. 283:20897-20906
We present the data and the technology, a combination of which allows us to determine the identity of proprotein convertases (PCs) related to the processing of specific protein targets including viral and bacterial pathogens. Our results, which suppo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::40611898964b080e1535ecf9e083a7e1
https://doi.org/10.1074/jbc.m803762200
https://doi.org/10.1074/jbc.m803762200
Autor:
Richard A. Houghten, Michal Lebl
This volume contains the proceedings of the Second International Peptide Symposium and the Seventeenth American Peptide Symposium, held on 9-14 June, 2001, at the Town and Country Resort in San Diego, California. The biennial meeting was held under t
Autor:
Michal Lebl, Anu Srinivasan, Igor A. Kozlov, Melissa D. Shults, Nicholas A. Nelson, David L. Barker, John P. Hachmann, Peter C. Melnyk, Chanfeng Zhao, Joseph Musmacker
Publikováno v:
Combinatorial Chemistry & High Throughput Screening. 11:24-35
We have developed a miniaturized and multiplexed solution assay for the measurement of protease activity in complex samples. This technology can accelerate research in functional proteomics and enable biologists to carry out multiplexed protease inhi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b3c641ef547b5d55928d3d5439b899d
https://doi.org/10.2174/138620708783398304
https://doi.org/10.2174/138620708783398304
Autor:
Peter C. Melnyk, Chanfeng Zhao, Igor A. Kozlov, Michal Lebl, John P. Hachmann, David L. Barker
Publikováno v:
Nucleosides, Nucleotides and Nucleic Acids. 26:1353-1357
We developed novel assays for high-throughput detection of one or many kinases or proteases. The assays use hundreds of different peptide substrates, each covalently linked to an oligonucleotide tag. After incubation with sample, the pool of substrat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e3e5cd3a214d2212d0d19adfc4c18b8f
https://doi.org/10.1080/15257770701533909
https://doi.org/10.1080/15257770701533909