Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Michal Kluknavsky"'
Autor:
Michal Kluknavsky, Peter Balis, Silvia Liskova, Andrea Micurova, Martin Skratek, Jan Manka, Iveta Bernatova
Publikováno v:
Antioxidants, Vol 13, Iss 8, p 947 (2024)
This study investigated the effects of chronic crowding-induced social stress and dimethyl fumarate (DMF) on borderline hypertensive rats, focusing on the transcription nuclear factor (erythroid-derived 2)-like 2 (NRF2) gene Nfe2l2, on the expression
Externí odkaz:
https://doaj.org/article/0bab3dff7ca64b43a57c44fb1b22e867
Autor:
Sona Cacanyiova, Martina Cebova, Fedor Simko, Tomas Baka, Iveta Bernatova, Michal Kluknavsky, Stefan Zorad, Katarina Krskova, Ezgi Shaman, Anna Zemancikova, Andrej Barta, Basak G. Aydemir, Andrea Berenyiova
Publikováno v:
Biological Research, Vol 56, Iss 1, Pp 1-23 (2023)
Abstract Background Angiotensin converting enzyme 2 (ACE2) plays a crucial role in the infection cycle of SARS-CoV-2 responsible for formation of COVID-19 pandemic. In the cardiovascular system, the virus enters the cells by binding to the transmembr
Externí odkaz:
https://doaj.org/article/5aaaae2bd527423c9187dda7bfa601ac
Autor:
Silvia Liskova, Sona Cacanyiova, Martina Cebova, Andrea Berenyiova, Michal Kluknavsky, Andrea Micurova, Katarina Valachova, Ladislav Soltes, Iveta Bernatova
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 16, p 12616 (2023)
The effect of a 10-day-long treatment with taxifolin (TAX, 20 mg/kg/day p.o.) was investigated on spontaneously hypertensive rats (SHRs) with a focus on the vascular functions of isolated femoral arteries and thoracic aortas. TAX reduced blood pressu
Externí odkaz:
https://doaj.org/article/7e3ae04448554d6ea339fdb79f7793fd
Autor:
Michal Kluknavsky, Andrea Micurova, Martin Skratek, Peter Balis, Monika Okuliarova, Jan Manka, Iveta Bernatova
Publikováno v:
Pharmaceutics, Vol 15, Iss 5, p 1475 (2023)
This study investigated genotype- and tissue-related differences in the biodistribution of superparamagnetic magnetite (Fe3O4) nanoparticles (IONs) into the heart and liver of normotensive Wistar Kyoto (WKY) and spontaneously hypertensive (SHR) rats
Externí odkaz:
https://doaj.org/article/e7b9136fd0f3490ebae121f0ccf47662
Autor:
Michal Kluknavsky, Andrea Micurova, Martina Cebova, Ezgi Şaman, Sona Cacanyiova, Iveta Bernatova
Publikováno v:
Antioxidants, Vol 11, Iss 12, p 2385 (2022)
Reduced angiotensin 1–7 bioavailability due to inhibition of angiotensin-converting enzyme 2 (ACE2) may contribute to increased mortality in hypertensive individuals during COVID-19. However, effects of ACE2 inhibitor MLN-4760 in brain functions re
Externí odkaz:
https://doaj.org/article/58faea74ffa74fa098f819ce774bc573
Autor:
Andrea Micurova, Michal Kluknavsky, Silvia Liskova, Peter Balis, Martin Skratek, Ludmila Okruhlicova, Jan Manka, Iveta Bernatova
Publikováno v:
Biomedicines, Vol 9, Iss 12, p 1855 (2021)
We investigate the distribution and biological effects of polyethylene glycol (PEG)-coated magnetite (Fe3O4@PEG) nanoparticles (~30 nm core size, ~51 nm hydrodynamic size, 2 mg Fe/kg/day, intravenously, for two days) in the aorta and liver of Wistar
Externí odkaz:
https://doaj.org/article/8c36987efbeb435dbd8f6b79bc7bab6c
Publikováno v:
Antioxidants, Vol 9, Iss 2, p 96 (2020)
This study investigated the effects of (−)-epicatechin (Epi) in young male borderline hypertensive rats (BHR) during two weeks of treatment (Epi group, 100 mg/kg/day p.o.) and two weeks post treatment (PE group). Epi reduced blood pressure (BP), wh
Externí odkaz:
https://doaj.org/article/01d6ac5e6b214a1cab70e9d54b1a7c75
Autor:
Andrea Berenyiova, Peter Balis, Michal Kluknavsky, Iveta Bernatova, Sona Cacanyiova, Angelika Puzserova
Publikováno v:
Oxidative medicine and cellular longevity. 2022
This study was aimed at examining the role of the NOS/NO/sGC signaling pathway in the vasoactive control of the thoracic aorta (TA) from the early to late ontogenetic stages (7 weeks, 20 weeks, and 52 weeks old) of normotensive Wistar-Kyoto (WKY) rat
Publikováno v:
Antioxidants, Vol 9, Iss 2, p 96 (2020)
Antioxidants
Volume 9
Issue 2
Antioxidants
Volume 9
Issue 2
This study investigated the effects of (&ndash
)-epicatechin (Epi) in young male borderline hypertensive rats (BHR) during two weeks of treatment (Epi group, 100 mg/kg/day p.o.) and two weeks post treatment (PE group). Epi reduced blood pressure
)-epicatechin (Epi) in young male borderline hypertensive rats (BHR) during two weeks of treatment (Epi group, 100 mg/kg/day p.o.) and two weeks post treatment (PE group). Epi reduced blood pressure
Autor:
Zdenka Durackova, Angelika Puzserova, Martina Horvathova, Jana Muchová, Ingrid Zitnanova, Michal Kluknavsky, Iveta Bernatova, Peter Balis, Zuzana Kralovicova
Publikováno v:
Hypertension Research. 39:64-69
This study investigated the contribution of blood oxidative stress (OS) to the development of hypertension, as well as sex differences in the antioxidant defense system (ADS) in genetic models of hypertension. Nine-week-old normotensive Wistar-Kyoto