Zobrazeno 1 - 10
of 36
pro vyhledávání: '"Michal Kielbik"'
Autor:
Patrycja Przygodzka, Kamila Soboska, Ewelina Sochacka, Marcin Pacholczyk, Marcin Braun, Hassan Kassassir, Izabela Papiewska-Pająk, Michal Kielbik, Joanna Boncela
Publikováno v:
Cell Communication and Signaling, Vol 20, Iss 1, Pp 1-17 (2022)
Abstract Background Neuromedin U (NMU) was identified as one of the hub genes closely related to colorectal cancer (CRC) progression and was recently shown to be a motility inducer in CRC cells. Its autocrine signalling through specific receptors inc
Externí odkaz:
https://doaj.org/article/af77aad5869f4c03a78c7d79fa083911
Autor:
Izabela Szulc-Kielbik, Jakub Pawelczyk, Michal Kielbik, Laurent Kremer, Jaroslaw Dziadek, Magdalena Klink
Publikováno v:
Microbial Cell Factories, Vol 16, Iss 1, Pp 1-11 (2017)
Abstract Background Although mycobacterial glycolipids are among the first-line molecules involved in host–pathogen interactions, their contribution in virulence remains incomplete. Mycobacterium marinum is a waterborne pathogen of fish and other e
Externí odkaz:
https://doaj.org/article/8d6b2d40f72744a6b39bad2dc15f0911
Autor:
Izabela Szulc-Kielbik, Michal Kielbik, Patrycja Przygodzka, Anna Brzostek, Jaroslaw Dziadek, Magdalena Klink
Publikováno v:
Mediators of Inflammation, Vol 2019 (2019)
This study tested the hypothesis that Mycobacterium tuberculosis (Mtb) uses a cholesterol oxidase enzyme (ChoD) to suppress a toll-like receptor type 2- (TLR2-) dependent signalling pathway to modulate macrophages’ immune response. We investigated
Externí odkaz:
https://doaj.org/article/50b1b22965374f36ae054ee34ba0b2d5
Publikováno v:
Cells, Vol 10, Iss 1, p 130 (2021)
Immunogenic cell death (ICD) is a type of death, which has the hallmarks of necroptosis and apoptosis, and is best characterized in malignant diseases. Chemotherapeutics, radiotherapy and photodynamic therapy induce intracellular stress response path
Externí odkaz:
https://doaj.org/article/f953fb054a5e496aaf1ce102625db71d
Publikováno v:
Redox Biology, Vol 5, Iss , Pp 420- (2015)
Background: Despite significant improvements in the conventional anti-ovarian cancer therapies, tumor cell resistance to various cytostatic drugs remains a relevant problem. Therefore, the new cancer treatment strategies are being developed. Among ma
Externí odkaz:
https://doaj.org/article/1c42e30f871843bc9ba00eb09dc6fd94
Publikováno v:
Mediators of Inflammation, Vol 2014 (2014)
Cholesterol oxidase (ChoD) is considered to be an important virulence factor for Mycobacterium tuberculosis (Mtb), but its influence on macrophage activity is unknown. Here we used Nocardia erythropolis ChoD, which is very similar to the Mtb enzyme (
Externí odkaz:
https://doaj.org/article/050d0c35e5274a6b9864865f198c71cb
Autor:
Magdalena Klink, Marta Brzezinska, Izabela Szulc, Anna Brzostek, Michal Kielbik, Zofia Sulowska, Jaroslaw Dziadek
Publikováno v:
PLoS ONE, Vol 8, Iss 9, p e73333 (2013)
Despite considerable research effort, the molecular mechanisms of Mycobacterium tuberculosis (Mtb) virulence remain unclear. Cholesterol oxidase (ChoD), an extracellular enzyme capable of converting cholesterol to its 3-keto-4-ene derivative, cholest
Externí odkaz:
https://doaj.org/article/918764a3e5234a7da9e132194adf96da
Publikováno v:
Experientia supplementum (2012). 113
Tumor microenvironment (TME) is a complex and constantly evolving entity that consists not only of cancer cells, but also of resident host cells and immune-infiltrating cells, among which macrophages are significant components, due to their diversity
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::315cac4e88d9cc97078a84cc7d9efc45
https://pubmed.ncbi.nlm.nih.gov/35165862
https://pubmed.ncbi.nlm.nih.gov/35165862
Autor:
Izabela Szulc-Kielbik, Michal Kielbik
Publikováno v:
Experientia Supplementum ISBN: 9783030913106
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e8d3e744ecc021ba5afa7c58566b3f6c
https://doi.org/10.1007/978-3-030-91311-3_4
https://doi.org/10.1007/978-3-030-91311-3_4
Autor:
Anna Brzostek, Magdalena Klink, Jarosław Dziadek, Michal Kielbik, Patrycja Przygodzka, Izabela Szulc-Kielbik
Publikováno v:
Mediators of Inflammation, Vol 2019 (2019)
Mediators of Inflammation
Mediators of Inflammation
This study tested the hypothesis that Mycobacterium tuberculosis (Mtb) uses a cholesterol oxidase enzyme (ChoD) to suppress a toll-like receptor type 2- (TLR2-) dependent signalling pathway to modulate macrophages’ immune response. We investigated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::71d98f23d99aa5343523c1738c5fcf29
https://doi.org/10.1155/2019/2373791
https://doi.org/10.1155/2019/2373791