Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Michal Kýr"'
Autor:
Hana Palova, Anirban Das, Petra Pokorna, Viera Bajciova, Zdenek Pavelka, Marta Jezova, Karol Pal, Jose R. Dimayacyac, Logine Negm, Lucie Stengs, Vanessa Bianchi, Klara Vejmelkova, Kristyna Noskova, Marie Jarosova, Sona Mejstrikova, Peter Mudry, Michal Kyr, Tomas Merta, Pavel Tinka, Klara Drabova, Stefania Aulicka, Robin Jugas, Uri Tabori, Ondrej Slaby, Jaroslav Sterba
Publikováno v:
npj Precision Oncology, Vol 8, Iss 1, Pp 1-9 (2024)
Abstract Constitutional mismatch repair deficiency (CMMRD) is a rare syndrome characterized by an increased incidence of cancer. It is caused by biallelic germline mutations in one of the four mismatch repair genes (MMR) genes: MLH1, MSH2, MSH6, or P
Externí odkaz:
https://doaj.org/article/b0a2950947714c9188792348f38d31f7
Autor:
Peter Múdry, Michal Kýr, Ondřej Rohleder, Michal Mahdal, Iva Staniczková Zambo, Marta Ježová, Tomáš Tomáš, Jaroslav Štěrba
Publikováno v:
Journal of Bone Oncology, Vol 28, Iss , Pp 100362- (2021)
Purpose: Conventional osteosarcoma is an orphan disease. Current treatment approaches include combining a three drug chemotherapy schedule and surgery. The 3- and 5-year event-free survival (EFS) in localized disease is roughly 65 and 60%, respective
Externí odkaz:
https://doaj.org/article/d2c6f7ddce29434c93d6a72a9563cdf9
Autor:
Michal Kýr, Giannoula Lakka Klement, Lenka Zdrazilova-Dubska, Regina Demlova, Dalibor Valik, Ondrej Slaby, Irene Slavc, Jaroslav Sterba
Publikováno v:
Frontiers in Oncology, Vol 10 (2020)
Externí odkaz:
https://doaj.org/article/5d8a8e190d794418846f582691ec283b
Autor:
Iva Staniczková Zambo, Michal Mahdal, Jaroslav Štěrba, Michal Kýr, Peter Múdry, Tomáš Tomáš, Ondřej Rohleder, Marta Ježová
Publikováno v:
Journal of Bone Oncology
Journal of Bone Oncology, Vol 28, Iss, Pp 100362-(2021)
Journal of Bone Oncology, Vol 28, Iss, Pp 100362-(2021)
Highlights • A report on the best treatment results on an osteosarcoma cohort. • There has been a lack of improvement in osteosarcoma treatment for the last four decades. • Mifamurtide is the only new drug against osteosarcoma licensed by the E
Background Conventional osteosarcoma is rare disease. Current treatment approaches have been set decades ago and include combination of three drug chemotherapy schedule and surgery. Three and five years event free survival in localized disease is rou
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dfc3192ef5afc741fb66364ab78b1e97
https://doi.org/10.21203/rs.2.14968/v1
https://doi.org/10.21203/rs.2.14968/v1
Publikováno v:
European Journal of Lipid Science and Technology. 123:2000259
lt; 0.05), while PPD reduction is not affected. The retained GT does not compromise healing. EGT is proposed as a promising, inexpensive, and simple method that may improve the outcome of periodontal regenerative treatment. However, the described pro
Autor:
Jaroslav Štěrba, Josef Tomandl, Michal Kýr, Julie Bienertová-Vašků, Klára Drábová, Zbyněk Šplíchal, Filip Zlámal
Publikováno v:
Tumor Biology. 37:9209-9219
Recently, vitamin D has been recognized as an important player in the immune system, and multiple studies suggested its involvement in cancer, too. The aims of this study were to investigate selected single nucleotide polymorphisms (SNPs) in the VDR
Autor:
Michal Kýr, Otakar Čapoun, Roman Sobotka, Tomáš Hanuš, Jan Hrbáček, Marek Babjuk, Ivo Minárik
Publikováno v:
Central European Journal of Urology
Introduction Extended transrectal ultrasound-guided prostate biopsy is a state-of-the-art tool for prostate cancer detection. Nevertheless, approximately 1/3 of cancers are missed when using this method and repeat biopsy sessions are often required.
Publikováno v:
Peptides. 46:1-5
Intestinal injury significantly contributes to critical illness, sepsis and multiorgan failure. TFF2 (Trefoil Factor 2) is expressed and secreted preferentially by gastric mucous neck cells. TFF2 gene expression is promptly increased after gut injury
Publikováno v:
Open Medicine, Vol 10, Iss 1 (2015)
Open Medicine
Open Medicine
Objective: Gastrointestinal dysfunction or gut failure frequently occurs in seriously ill patients and can be responsible for multi-organ failure. Trefoil factor 3 (TFF3) was characterized for its role in reconstitution of an epithelial barrier after