Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Michal J. Dabrowski"'
Autor:
Malgorzata Perycz, Michal J. Dabrowski, Marta Jardanowska-Kotuniak, Adria-Jaume Roura, Bartlomiej Gielniewski, Karolina Stepniak, Michał Dramiński, Iwona A. Ciechomska, Bozena Kaminska, Bartosz Wojtas
Publikováno v:
Acta Neuropathologica Communications, Vol 12, Iss 1, Pp 1-29 (2024)
Abstract The RE1-silencing transcription factor (REST) acts either as a repressor or activator of transcription depending on the genomic and cellular context. REST is a key player in brain cell differentiation by inducing chromatin modifications, inc
Externí odkaz:
https://doaj.org/article/9e43803f2e9b471f8242922568240305
Autor:
Adria-Jaume Roura, Paulina Szadkowska, Katarzyna Poleszak, Michal J. Dabrowski, Aleksandra Ellert-Miklaszewska, Kamil Wojnicki, Iwona A. Ciechomska, Karolina Stepniak, Bozena Kaminska, Bartosz Wojtas
Publikováno v:
Clinical Epigenetics, Vol 15, Iss 1, Pp 1-22 (2023)
Abstract Background Glioblastoma (GBM, WHO grade IV) is an aggressive, primary brain tumor. Despite extensive tumor resection followed by radio- and chemotherapy, life expectancy of GBM patients did not improve over decades. Several studies reported
Externí odkaz:
https://doaj.org/article/7137ac18dafd4e8eaf59d8af42507495
Autor:
Natalia Zeber-Lubecka, Katarzyna Suchta, Maria Kulecka, Anna Kluska, Magdalena Piątkowska, Michal J. Dabrowski, Katarzyna Jankowska, Monika Grymowicz, Roman Smolarczyk, Ewa E. Hennig
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
A large body of evidence indicates that women with polycystic ovary syndrome (PCOS) have a higher risk of developing Hashimoto’s thyroiditis (HT) than healthy individuals. Given the strong genetic impact on both diseases, common predisposing geneti
Externí odkaz:
https://doaj.org/article/6fd67e991031441f8ad3cdb47a9e93cd
Autor:
Adrian A. Michalski, Karol Lis, Joanna Stankiewicz, Sylwester M. Kloska, Arkadiusz Sycz, Marek Dudziński, Katarzyna Muras-Szwedziak, Michał Nowicki, Stanisława Bazan-Socha, Michal J. Dabrowski, Grzegorz W. Basak
Publikováno v:
Journal of Clinical Medicine, Vol 12, Iss 10, p 3599 (2023)
In clinical practice, the consideration of non-specific symptoms of rare diseases in order to make a correct and timely diagnosis is often challenging. To support physicians, we developed a decision-support scoring system on the basis of retrospectiv
Externí odkaz:
https://doaj.org/article/994dde7595b14d5c931be5c763d3134b
Autor:
Michal J. Dabrowski, Bartosz Wojtas
Publikováno v:
International Journal of Molecular Sciences, Vol 20, Iss 14, p 3478 (2019)
During the last two decades, several international consortia have been established to unveil the molecular background of human cancers including gliomas. As a result, a huge outbreak of new genetic and epigenetic data appeared. It was not only shown
Externí odkaz:
https://doaj.org/article/475173735a91495cb2369ba3f8d5027a
Autor:
Paulina Kaminska, Peter L. Ovesen, Mateusz Jakiel, Tomasz Obrebski, Vanessa Schmidt, Magdalena Bieniek, Jasper Anink, Bohdan Paterczyk, Michal Draminski, Anne Mette Gissel Jensen, Sylwia Piatek, Olav M. Andersen, Eleonora Aronica, Thomas E. Willnow, Bozena Kaminska, Michal J. Dabrowski, Anna R. Malik
SorLA, encoded by the geneSORL1, is an intracellular sorting receptor of the VPS10P domain receptor gene family. Although SorLA is best recognized for its ability to shuttle target proteins between intracellular compartments in neurons, recent data s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::363d1639ef084bea7d7fc8a8ae5f74b3
https://doi.org/10.1101/2023.04.12.536447
https://doi.org/10.1101/2023.04.12.536447
Autor:
Malgorzata Perycz, Michal J. Dabrowski, Marta Jardanowska, Adria-Jaume Roura, Bartlomiej Gielniewski, Karolina Stepniak, Michał Dramiński, Bozena Kaminska, Bartosz Wojtas
SummaryREST acts as a transcriptional repressor of neuronal genes in non-neuronal cells but could be a transcriptional activator under certain conditions. REST was implicated in a blockage of cell differentiation and is an important oncogenic factor.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b569e3fd91c7d2459c933ee102c5537f
https://doi.org/10.1101/2022.07.28.501927
https://doi.org/10.1101/2022.07.28.501927
Autor:
Adria-Jaume Roura, Paulina Szadkowska, Katarzyna Poleszak, Michal J. Dabrowski, Aleksandra Ellert-Miklaszewska, Kamil Wojnicki, Iwona A. Ciechomska, Karolina Stepniak, Bozena Kaminska, Bartosz Wojtas
Background Glioblastoma (GBM, WHO grade IV) is an aggressive, primary brain tumor. Despite extensive tumor resection followed by radio- and chemotherapy, life expectancy of GBM patients did not improve over decades. Several studies reported transcrip
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c3c6d1e3c5483ee94303be6fca0415f8
https://doi.org/10.1101/2022.07.18.500476
https://doi.org/10.1101/2022.07.18.500476
Publikováno v:
Experimental Oncology.
BACKGROUND Somatic mutations in coding regions of the genome may result in non-functional proteins that can lead to cancer or other diseases, however cancer mutations in the non-coding regions have rarely been studied and the interpretation of their
Autor:
Agata Dziedzic, Michał Dramiński, Jakub Mieczkowski, Wiesława Grajkowska, Michal J. Dabrowski, Magdalena A. Machnicka, Rafal Guzik, Bartłomiej Gielniewski, Klev Diamanti, Bartosz Wojtas, Katarzyna Kotulska, Jan Komorowski, Anna Macioszek, Karolina Sienkiewicz, Marcin Roszkowski, Sylwia K Król, Andrzej Marchel, Ilona E. Grabowicz, Karolina Stepniak, Hanna Kranas, Bartek Wilczyński, Marta Jardanowska, Bozena Kaminska, Tomasz Czernicki
SummaryChromatin structure and accessibility, and combinatorial binding of transcription factors to regulatory elements in genomic DNA control transcription. Genetic variations in genes encoding histones, epigenetics-related enzymes or modifiers affe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0158f80e5b25ed9f10a18b520b46067a