Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Michal Izrael"'
Autor:
Marc Gotkine, Yoseph Caraco, Yossef Lerner, Simcha Blotnick, Maor Wanounou, Shalom Guy Slutsky, Judith Chebath, Graciela Kuperstein, Elena Estrin, Tamir Ben-Hur, Arik Hasson, Kfir Molakandov, Tehila Sonnenfeld, Yafit Stark, Ariel Revel, Michel Revel, Michal Izrael
Publikováno v:
Journal of Translational Medicine, Vol 21, Iss 1, Pp 1-12 (2023)
Abstract Background Malfunction of astrocytes is implicated as one of the pathological factors of ALS. Thus, intrathecal injection of healthy astrocytes in ALS can potentially compensate for the diseased astrocytes. AstroRx® is an allogeneic cell-ba
Externí odkaz:
https://doaj.org/article/3ddbc58896384d3a9d1071138a07d1a3
Autor:
Anastasya Birger, Israel Ben-Dor, Miri Ottolenghi, Tikva Turetsky, Yaniv Gil, Sahar Sweetat, Liat Perez, Vitali Belzer, Natania Casden, Debora Steiner, Michal Izrael, Eithan Galun, Eva Feldman, Oded Behar, Benjamin Reubinoff
Publikováno v:
EBioMedicine, Vol 50, Iss , Pp 274-289 (2019)
Background: Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disease that affects motor neurons (MNs). It was shown that human astrocytes with mutations in genes associated with ALS, like C9orf72 (C9) or SOD1, reduce survival of
Externí odkaz:
https://doaj.org/article/0750a3f2516642e688f2805e1ec47deb
Autor:
Michal Izrael, Kfir Molakandov, Ariel Revel, Shalom Guy Slutsky, Tehila Sonnenfeld, Julia Miriam Weiss, Michel Revel
Publikováno v:
Frontiers in Medicine, Vol 8 (2021)
Background: An acute respiratory distress syndrome (ARDS) is caused by the increased amounts of pro-inflammatory cytokines and neutrophil-mediated tissue injury. To date, there is no effective treatment for the ARDS available, while the need for one
Externí odkaz:
https://doaj.org/article/4e669f64b52142248ccc4e18b56f57ea
Publikováno v:
Frontiers in Neuroscience, Vol 14 (2020)
Amyotrophic lateral sclerosis (ALS) is a multifactorial disease, characterized by a progressive loss of motor neurons that eventually leads to paralysis and death. The current ALS-approved drugs modestly change the clinical course of the disease. The
Externí odkaz:
https://doaj.org/article/047abe6601864a4c941034ee6aa3b471
Autor:
Michal Izrael, Shalom Guy Slutsky, Tamar Admoni, Louisa Cohen, Avital Granit, Arik Hasson, Joseph Itskovitz-Eldor, Lena Krush Paker, Graciela Kuperstein, Neta Lavon, Shiran Yehezkel Ionescu, Leonardo Javier Solmesky, Rachel Zaguri, Alina Zhuravlev, Ella Volman, Judith Chebath, Michel Revel
Publikováno v:
Stem Cell Research & Therapy, Vol 9, Iss 1, Pp 1-17 (2018)
Abstract Background Amyotrophic lateral sclerosis (ALS) is a motor neuron (MN) disease characterized by the loss of MNs in the central nervous system. As MNs die, patients progressively lose their ability to control voluntary movements, become paraly
Externí odkaz:
https://doaj.org/article/abd5746dc0f746fab78916491ba612f7
Autor:
Carlos E. Pedraza, Christopher Taylor, Albertina Pereira, Michelle Seng, Chui-Se Tham, Michal Izrael, Michael Webb
Publikováno v:
ASN Neuro, Vol 6 (2014)
In inflammatory demyelinating diseases such as multiple sclerosis (MS), myelin degradation results in loss of axonal function and eventual axonal degeneration. Differentiation of resident oligodendrocyte precursor cells (OPCs) leading to remyelinatio
Externí odkaz:
https://doaj.org/article/a2e6084c430e4add8fba7ed88168328c
Autor:
Marc Gotkine, Yoseph Caraco, Yossef Lerner, Simcha Blotnick, Maor Wanounou, Shalom Guy Guy Slutsky, Judith Chebath, Graciela Kuperstein, elena estrin, Tamir Ben-Hur, Arik Hasson, Kfir Molakandov, Tehila Sonnenfeld, Yafit Stark, Ariel Revel, Michel Revel, Michal Izrael
Background: AstroRx is an allogeneic cell-based product, composed of healthy and functional human astrocytes derived from embryonic stem cells. We previously showed that AstroRx protects neurons in ALS animal models by multiple mechanisms, including
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c367fbb256e70677d5f503149589df3f
https://doi.org/10.21203/rs.3.rs-2275247/v1
https://doi.org/10.21203/rs.3.rs-2275247/v1
Autor:
Graciela Kuperstein, Judith Chebath, Yossef Lerner, Yoseph Caraco, Yafit Stark, Elena Estrin, Tehila Sonnefeld, Guy Slutsky, Michel Revel, Arik Hasson, Michal Izrael, Ariel Revel, Tamir Ben-Hur, Marc Gotkine
Publikováno v:
Journal of the Neurological Sciences. 429:119398
Autor:
Sahar Sweetat, Natania Casden, Michal Izrael, Yaniv Gil, Eithan Galun, Eva L. Feldman, Anastasya Birger, Miri Ottolenghi, Liat Perez, Benjamin Reubinoff, Tikva Turetsky, Israel Ben-Dor, Oded Behar, Vitali Belzer, Debora Steiner
Publikováno v:
EBioMedicine
EBioMedicine, Vol 50, Iss, Pp 274-289 (2019)
EBioMedicine, Vol 50, Iss, Pp 274-289 (2019)
Background: Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disease that affects motor neurons (MNs). It was shown that human astrocytes with mutations in genes associated with ALS, like C9orf72 (C9) or SOD1, reduce survival of
Autor:
Arik Hasson, Shiran Yehezkel Ionescu, Alina Zhuravlev, Rachel Zaguri, Ella Volman, Tamar Admoni, Leonardo Javier Solmesky, Graciela Kuperstein, Judith Chebath, Lena Krush Paker, Michal Izrael, Louisa Cohen, Avital Granit, Joseph Itskovitz-Eldor, Neta Lavon, Michel Revel, Shalom Guy Slutsky
Publikováno v:
Stem Cell Research & Therapy, Vol 9, Iss 1, Pp 1-17 (2018)
Background Amyotrophic lateral sclerosis (ALS) is a motor neuron (MN) disease characterized by the loss of MNs in the central nervous system. As MNs die, patients progressively lose their ability to control voluntary movements, become paralyzed and e