Zobrazeno 1 - 10
of 122
pro vyhledávání: '"Michal Cifra"'
Autor:
Kateřina Červinková, Petra Vahalová, Michaela Poplová, Tomáš Zakar, Daniel Havelka, Martin Paidar, Viliam Kolivoška, Michal Cifra
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-19 (2024)
Abstract Technologies based on pulsed electric field (PEF) are increasingly pervasive in medical and industrial applications. However, the detailed understanding of how PEF acts on biosamples including proteins at the molecular level is missing. Ther
Externí odkaz:
https://doaj.org/article/7947b357c45044a7813a0d98a19b7c01
Autor:
Jiří Průša, Michal Cifra
Publikováno v:
Data in Brief, Vol 52, Iss , Pp 109765- (2024)
We present trajectories from non-equilibrium (in electric field) molecular dynamics (MD) simulations of a kinesin motor domain on tubulin heterodimers with two tubulin heterodimers forming neighbouring microtubule protofilaments. The trajectories are
Externí odkaz:
https://doaj.org/article/75ab9579f7c5453fab15055294f2c387
Autor:
Jiří Průša, Michal Cifra
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 21, Iss , Pp 1349-1361 (2023)
Kinesin is a motor protein essential in cellular functions, such as intracellular transport and cell-division, as well as for enabling nanoscopic transport in bio-nanotechnology. Therefore, for effective control of function for nanotechnological appl
Externí odkaz:
https://doaj.org/article/d3aeebc94dea4ce8918136d36fbf2863
Autor:
Daniel Havelka, Ilia Zhernov, Michal Teplan, Zdeněk Lánský, Djamel Eddine Chafai, Michal Cifra
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-12 (2022)
Abstract Pulsed electric field (PEF) technology is promising for the manipulation of biomolecular components and has potential applications in biomedicine and bionanotechnology. Microtubules, nanoscopic tubular structures self-assembled from protein
Externí odkaz:
https://doaj.org/article/eba222524d9945e799afc6dae530f950
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-10 (2021)
Abstract Nowadays, modern medicine is looking for new, more gentle, and more efficient diagnostic methods. A pathological state of an organism is often closely connected with increased amount of reactive oxygen species. They can react with biomolecul
Externí odkaz:
https://doaj.org/article/8df2e8167c544f9c8e72a11138fb4be4
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-11 (2021)
Abstract Normal or excessive oxidative metabolism in organisms is essential in physiological and pathophysiological processes, respectively. Therefore, monitoring of biological oxidative processes induced by the chemical or physical stimuli is nowada
Externí odkaz:
https://doaj.org/article/ff99636881aa40129f501b3854eca94c
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 19, Iss , Pp 1488-1496 (2021)
Modulation of the structure and function of biomaterials is essential for advancing bio-nanotechnology and biomedicine. Microtubules (MTs) are self-assembled protein polymers that are essential for fundamental cellular processes and key model compoun
Externí odkaz:
https://doaj.org/article/117b00da3feb429b8d7b7c4a4cc720c5
Publikováno v:
Data in Brief, Vol 38, Iss , Pp 107337- (2021)
We present molecular dynamics (MD) trajectories of a single ring of B-lattice microtubule ring consisting of 13 tubulin heterodimers. The data contain trajectories of this molecular system ran under various conditions (two temperature values, three i
Externí odkaz:
https://doaj.org/article/22bb93b5bc73474583dea2a0fad01fa2
Autor:
Jiří Průša, Michal Cifra
Publikováno v:
Data in Brief, Vol 30, Iss , Pp 105483- (2020)
We present molecular dynamics (MD) trajectories of water solutions of eight zwitterionic amino-acids (L- form) glycine (GLY), alanine (ALA), proline (PRO), threonine (THR), leucine (LEU), glutamine (GLN), histidine (HIS) and tyrosine (TYR) using vari
Externí odkaz:
https://doaj.org/article/5868578cbb77475687ae351e14249c0c
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-11 (2017)
Abstract The mechanical properties of microtubules are of great importance for understanding their biological function and for applications in artificial devices. Although microtubule mechanics has been extensively studied both theoretically and expe
Externí odkaz:
https://doaj.org/article/e923275ab6c84b638424cbb4e8a9f6a5