Zobrazeno 1 - 10
of 40
pro vyhledávání: '"Michal Caspi, Tal"'
Autor:
Satu Strausz, Erik Abner, Grace Blacker, Sarah Galloway, Paige Hansen, Qingying Feng, Brandon T. Lee, Samuel E. Jones, Hele Haapaniemi, Sten Raak, George Ronald Nahass, Erin Sanders, FinnGen, Estonian Genome Centre, Estonian Biobank Research Team, Pilleriin Soodla, Urmo Võsa, Tõnu Esko, Nasa Sinnott-Armstrong, Irving L. Weissman, Mark Daly, Tuomas Aivelo, Michal Caspi Tal, Hanna M. Ollila
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-11 (2024)
Abstract Lyme disease is a tick-borne disease caused by bacteria of the genus Borrelia. The host factors that modulate susceptibility for Lyme disease have remained mostly unknown. Using epidemiological and genetic data from FinnGen and Estonian Biob
Externí odkaz:
https://doaj.org/article/6ff1c773b86b466eacdd4659aaa166eb
Publikováno v:
STAR Protocols, Vol 3, Iss 4, Pp 101832- (2022)
Summary: Cell motility and biomechanics are critical in various (patho)physiological processes, including the regulation of vascular barrier integrity, which can be subverted by bacterial pathogens. Here, we present a protocol on how to expose endoth
Externí odkaz:
https://doaj.org/article/067a329ecc0f4280ab6dc7139a81033b
Autor:
Raúl Aparicio Yuste, Marie Muenkel, Konstantinos Axarlis, María J. Gómez Benito, Annalena Reuss, Grace Blacker, Michal Caspi Tal, Peter Kraiczy, Effie E. Bastounis
Publikováno v:
iScience, Vol 25, Iss 8, Pp 104793- (2022)
Summary: Borrelia burgdorferi (Bb), a vector-borne bacterial pathogen and the causative agent of Lyme disease, can spread to distant tissues in the human host by traveling in and through monolayers of endothelial cells (ECs) lining the vasculature. T
Externí odkaz:
https://doaj.org/article/53a6bebb630d447588f4790ec2498c2c
Autor:
Lara M. Myers, Michal Caspi Tal, Laughing Bear Torrez Dulgeroff, Aaron B. Carmody, Ronald J. Messer, Gunsagar Gulati, Ying Ying Yiu, Matthew M. Staron, Cesar Lopez Angel, Rahul Sinha, Maxim Markovic, Edward A. Pham, Benjamin Fram, Aijaz Ahmed, Aaron M. Newman, Jeffrey S. Glenn, Mark M. Davis, Susan M. Kaech, Irving L. Weissman, Kim J. Hasenkrug
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-15 (2019)
SIRPa is most commonly known as a phagocytosis inhibitory receptor expressed by myeloid cells. Here the authors show SIRPa is expressed on a subset of CD8+ T cells with higher proliferative and effector activity during the chronic phase of the immune
Externí odkaz:
https://doaj.org/article/1fe7158a38ec4c6c9bd116baa3bb1dee
Autor:
Michal Caspi Tal, Laughing Bear Torrez Dulgeroff, Lara Myers, Lamin B. Cham, Katrin D. Mayer-Barber, Andrea C. Bohrer, Ehydel Castro, Ying Ying Yiu, Cesar Lopez Angel, Ed Pham, Aaron B. Carmody, Ronald J. Messer, Eric Gars, Jens Kortmann, Maxim Markovic, Michaela Hasenkrug, Karin E. Peterson, Clayton W. Winkler, Tyson A. Woods, Paige Hansen, Sarah Galloway, Dhananjay Wagh, Benjamin J. Fram, Thai Nguyen, Daniel Corey, Raja Sab Kalluru, Niaz Banaei, Jayakumar Rajadas, Denise M. Monack, Aijaz Ahmed, Debashis Sahoo, Mark M. Davis, Jeffrey S. Glenn, Tom Adomati, Karl S. Lang, Irving L. Weissman, Kim J. Hasenkrug
Publikováno v:
mBio, Vol 11, Iss 3 (2020)
ABSTRACT It is well understood that the adaptive immune response to infectious agents includes a modulating suppressive component as well as an activating component. We now show that the very early innate response also has an immunosuppressive compon
Externí odkaz:
https://doaj.org/article/d8f71f31b4e248b893caeb967d0cb234
Publikováno v:
Language Learning in Higher Education. 11:15-32
This paper describes a joint programme developed in 2018 by the University of Parma Language Centre (Italy) and the Humanities and Arts Department of the Technion-Israel Institute of Technology. The aim of the project was to involve students of Engli
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::44770345254174c74cb796e552fed7fc
https://doi.org/10.1515/cercles-2021-2003
https://doi.org/10.1515/cercles-2021-2003
Autor:
Satu Strausz, Grace Blacker, Sarah Galloway, Paige Hansen, Samuel E. Jones, Erin Sanders, Nasa Sinnott-Armstrong, null FinnGen, Irving L. Weissman, Mark Daly, Tuomas Aivelo, Michal Caspi Tal, Hanna M. Ollila
SUMMARYLyme disease is a tick-borne disease caused by bacteria of the genus Borrelia. The disease can initially manifest as an erythema migrans rash and, if able to evade the host immune defenses, can progress into a secondary stage chronic disease w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::520f035a0fbd03c52ec0ac91d1774108
https://doi.org/10.1101/2022.05.27.493784
https://doi.org/10.1101/2022.05.27.493784
Autor:
Ying Ying Yiu, Paige S. Hansen, Laughing Bear Torrez Dulgeroff, Grace Blacker, Lara Myers, Sarah Galloway, Eric Gars, Olivia Colace, Paul Mansfield, Kim J. Hasenkrug, Irving L. Weissman, Michal Caspi Tal
Publikováno v:
J Immunol
CD47 is an important innate immune checkpoint through its interaction with its inhibitory receptor on macrophages, signal-regulatory protein α (SIRPα). Therapeutic blockade of CD47–SIRPα interactions is a promising immuno-oncology treatment that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::506185d192a6ad6c7bf843a33ec3c6b3
https://europepmc.org/articles/PMC9012117/
https://europepmc.org/articles/PMC9012117/
Autor:
Brandon T Lee, Sarah Galloway, Satu Strausz, Paige Hansen, Laughing Bear Torrez-Dulgeroff, Grace Blacker, Ying Ying Yiu, Paul Mansfield, FinnGen Affiliation, Atif Saleem, Eric Gars, Erin Sanders, Irving L Weissman, Hanna Ollila, Michal Caspi Tal
Background Borrelia burgdorferi is a bacterial spirochete that can cause Lyme disease after infecting a susceptible host. Immune responses to the bacteria are highly variable and host specific. The murine substrain, C3H/HeJ, is one of the most freque
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::95bf064a7441145c5222caa6d51c42fe
https://doi.org/10.21203/rs.3.rs-1316212/v1
https://doi.org/10.21203/rs.3.rs-1316212/v1
Autor:
Brandon T. Lee, Sarah D. Galloway, Satu Strausz, Maia Shoham, Paige Hansen, Laughing Bear Torrez Dulgeroff, Grace Blacker, Ying Y. Yiu, Paul Mansfield, Finn Gen, Atif Saleem, Eric Gars, Erin C. Sanders, Irving L. Weissman, Hanna M. Ollila, Michal Caspi Tal
Borrelia burgdorferi is a bacterial spirochete that can cause Lyme disease (LD) after infecting a susceptible host. Immune responses to the bacteria are highly variable and host specific. The murine substrain, C3H/HeJ, is a frequently utilized model
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ecaaa550fe083f7676eb8c9c0cba1e34
https://doi.org/10.1101/2022.01.27.476641
https://doi.org/10.1101/2022.01.27.476641