Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Michal Cardon"'
Publikováno v:
Brain, Behavior, and Immunity. 25:1036-1043
An organism's behavior is determined by the way it senses and perceives the surrounding environment, and by its responses to these stimuli. The major factors known to affect the behavioral response to an event are genetic background, environmental fa
Publikováno v:
Trends in Molecular Medicine. 12:107-112
T-cell-mediated autoimmunity participates in physiological defense, maintenance and repair of the adult brain. However, unless such autoimmune responses to insults are rigorously controlled, they might lead to an autoimmune disease or other immune-re
Publikováno v:
Proceedings of the National Academy of Sciences. 101:8180-8185
The effects of the adaptive immune system on the cognitive performance and abnormal behaviors seen in mental disorders such as schizophrenia have never been documented. Here, we show that mice deprived of mature T cells manifested cognitive deficits
Autor:
Aleksandra Deczkowska, Michal Schwartz, Mark P. Mattson, Hilah Gal, Fernando Gomez-Pinilla, Michal Cardon, Wilfred Ndifon, Nir Friedman, Nataly Mirlas-Neisberg, Tamara Berkutzki, Kuti Baruch, Eric Shifrut, Liora Cahalon, Ilan Vaknin, Noga Ron-Harel
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 110(6)
The adaptive arm of the immune system has been suggested as an important factor in brain function. However, given the fact that interactions of neurons or glial cells with T lymphocytes rarely occur within the healthy CNS parenchyma, the underlying m
Autor:
Miguel Weil, Raz Somech, Michal Schwartz, Gideon Rechavi, Ninette Amariglio, Maya Koronyo-Hamaoui, MinHee K. Ko, Akop Seksenyan, Eli Konen, Michal Cardon, Patricia Rogeri, Liora Cahalon, David Azoulay, Shlomo Bulvik, Noga Ron-Harel
Publikováno v:
Journal of Cellular and Molecular Medicine
Amyotrophic lateral sclerosis (ALS) is a devastating disease, characterized by extremely rapid loss of motor neurons. Our studies over the last decade have established CD4+ T cells as important players in central nervous system maintenance and repair
Publikováno v:
Molecular psychiatry. 15(4)
Neuropsychological syndromes including schizophrenia often do not manifest until late adolescence or early adulthood. Studies attributing a role in brain maintenance to the immune system led us to propose that malfunction of immune-dependent regulati
Autor:
Micha Gawlik, Dorit Ben-Shachar, Gerald Stöber, Norbert Müller, Johannes Kornhuber, Peter Riederer, Michal Cardon, Toshikazu Saito, Andrea Schmitt, Assen Jablensky, Alfred N. Fonteh, Edna Grünblatt, Johannes Thome, Bob Oranje, Thomas F. McNeil, Marat Uzbekov, Michal Schwartz, Birte Glenthøj, Peter Falkai, Nuria Durany, Yong Ku Kim, Mohamed Saoud
Publikováno v:
The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry. 10(2)
Objective. The phenotypic complexity, together with the multifarious nature of the so-called "schizophrenic psychoses", limits our ability to form a simple and logical biologically based hypothesis for the disease group. Biological markers are define
Autor:
Dvir Netanely, Yaniv Ziv, J. Jacob-Hirsch, Gil M. Lewitus, Michal Cardon, Eytan Domany, Yifat Segev, G. Rechavi, Michal Schwartz, Ninette Amariglio, Noga Ron-Harel
Publikováno v:
Rejuvenation research. 11(5)
Aging is often associated with a decline in hippocampus-dependent spatial memory. Here, we show that functional cell-mediated immunity is required for the maintenance of hippocampus-dependent spatial memory. Sudden imposition of immune compromise in
Autor:
Michal Schwartz, Michal Cardon, Yaniv Ziv, Jonathan Kipnis, Zeev Kaplan, Michael A. Matar, Hagit Cohen, Yori Gidron
Publikováno v:
Journal of neurobiology. 66(6)
Peripheral cellular immunity was recently shown to play a critical role in brain plasticity and performance. The antigenic specificity of the participating T cells, however, was not investigated, and nor was their relevance to psychological stress. H
Autor:
Sharon Mordechay, Jonathan Kipnis, Asya Rolls, Michal Schwartz, Hila Avidan, Gil M. Lewitus, Yael Shani, Michal Cardon
Publikováno v:
The Journal of neuroscience : the official journal of the Society for Neuroscience. 24(27)
Fighting off neuronal degeneration requires a well controlled T-cell response against self-antigens residing in sites of the CNS damage. The ability to evoke this response is normally suppressed by naturally occurring CD4+CD25+regulatory T-cells (Tre