Binding Interactions of Peptide Aptamers

Autor: Roger R. C. New, Tam T. T. Bui, Michal Bogus

Publikováno v: Molecules, Vol 25, Iss 24, p 6055 (2020)

Peptide aptamers are short amino acid chains that are capable of binding specifically to ligands in the same way as their much larger counterparts, antibodies. Ligands of therapeutic interest that can be targeted are other peptide chains or loops loc

Externí odkaz: https://doaj.org/article/2d4195c60d4e4aca90a31db1022f64e7

Efficacy of Bioactive Cyclic Peptides in Rheumatoid Arthritis: Translation from In Vitro to In Vivo Models

Autor: Roger New, Michal Bogus, Gurpal S. Bansal, Malgorzata Dryjska, Katarzyna Zajkowska, Michael Burnet

Publikováno v: Molecules, Vol 22, Iss 10, p 1613 (2017)

Using a novel drug discovery technology reported in previous issues of this journal cyclic peptides have been created which are able to down-regulate secretion of inflammatory cytokines, in vitro, by stimulated cells of the macrophage cell line J774.

Externí odkaz: https://doaj.org/article/99ecb3ec52e240eaaab7edb144d12485

99-LB: A Phase 2b Study of Oral Insulin (Capsulin) Administered to Patients with Type 2 Diabetes

Autor: Roger New, Michal Bogus, Gajanan S. Namjoshi, Glen Travers

Publikováno v: Diabetes. 70

Data from 93 patients, divided into three equal groups, were used to compare the efficacy of three different doses of insulin - 75iu, 150iu and 300iu - administered twice daily in enteric-coated capsules containing Diabetology’s Axcess™ oral deli

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::1fc389da1f16c2bf8af043e64c455cd9
https://doi.org/10.2337/db21-99-lb

Efficacy of Bioactive Cyclic Peptides in Rheumatoid Arthritis: Translation from In Vitro to In Vivo Models

Autor: Michael Burnet, Gurpal S. Bansal, Roger New, Malgorzata Dryjska, Katarzyna Zajkowska, Michal Bogus

Publikováno v: Molecules, Vol 22, Iss 10, p 1613 (2017)
Molecules; Volume 22; Issue 10; Pages: 1613
Molecules : A Journal of Synthetic Chemistry and Natural Product Chemistry

Using a novel drug discovery technology reported in previous issues of this journal cyclic peptides have been created which are able to down-regulate secretion of inflammatory cytokines, in vitro, by stimulated cells of the macrophage cell line J774.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bfe8ef3d74efa8f954c7057c4e2705e6
https://www.mdpi.com/1420-3049/22/10/1613

Atypical Endometrial Hyperplasia Arising in a Cesarean Section Scar: A Mechanism of Malignant Transformation

Autor: Marta Monist, Dorota Lewkowicz, Maciej Jóźwik, Marek Gogacz, Michał Bogusiewicz, Tomasz Rechberger, Andrzej Semczuk

Publikováno v: Case Reports in Oncology, Vol 12, Iss 1, Pp 317-321 (2019)

The incidence of scar endometriosis in Cesarean sections varies between 0.03 and 0.4%. However, the recently increased rate of Cesarean sections worldwide may be causing an increase in occurrence of scar endometriosis. This report presents anatomopat

Externí odkaz: https://doaj.org/article/977e0e9ee9e14780b5b264b5434d5ab5