Zobrazeno 1 - 10
of 99
pro vyhledávání: '"Michal Bassani‐Sternberg"'
Autor:
Marta A. S. Perez, Johanna Chiffelle, Sara Bobisse, Francesca Mayol‐Rullan, Marine Bugnon, Maiia E. Bragina, Marion Arnaud, Christophe Sauvage, David Barras, Denarda Dangaj Laniti, Florian Huber, Michal Bassani‐Sternberg, George Coukos, Alexandre Harari, Vincent Zoete
Publikováno v:
Advanced Science, Vol 11, Iss 40, Pp n/a-n/a (2024)
Abstract Approaches to analyze and cluster T‐cell receptor (TCR) repertoires to reflect antigen specificity are critical for the diagnosis and prognosis of immune‐related diseases and the development of personalized therapies. Sequence‐based ap
Externí odkaz:
https://doaj.org/article/7c1d5f76a223445b9ae15faddaab978c
Immunopeptidomics-based identification of naturally presented non-canonical circRNA-derived peptides
Autor:
Humberto J. Ferreira, Brian J. Stevenson, HuiSong Pak, Fengchao Yu, Jessica Almeida Oliveira, Florian Huber, Marie Taillandier-Coindard, Justine Michaux, Emma Ricart-Altimiras, Anne I. Kraemer, Lana E. Kandalaft, Daniel E. Speiser, Alexey I. Nesvizhskii, Markus Müller, Michal Bassani-Sternberg
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-18 (2024)
Abstract Circular RNAs (circRNAs) are covalently closed non-coding RNAs lacking the 5’ cap and the poly-A tail. Nevertheless, it has been demonstrated that certain circRNAs can undergo active translation. Therefore, aberrantly expressed circRNAs in
Externí odkaz:
https://doaj.org/article/aa13b660fd674c718d5106fcd51ebb43
Autor:
Julien Schmidt, Johanna Chiffelle, Marta A. S. Perez, Morgane Magnin, Sara Bobisse, Marion Arnaud, Raphael Genolet, Julien Cesbron, David Barras, Blanca Navarro Rodrigo, Fabrizio Benedetti, Alexandra Michel, Lise Queiroz, Petra Baumgaertner, Philippe Guillaume, Michael Hebeisen, Olivier Michielin, Tu Nguyen-Ngoc, Florian Huber, Melita Irving, Stéphanie Tissot-Renaud, Brian J. Stevenson, Sylvie Rusakiewicz, Denarda Dangaj Laniti, Michal Bassani-Sternberg, Nathalie Rufer, David Gfeller, Lana E. Kandalaft, Daniel E. Speiser, Vincent Zoete, George Coukos, Alexandre Harari
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-15 (2023)
Abstract The success of cancer immunotherapy depends in part on the strength of antigen recognition by T cells. Here, we characterize the T cell receptor (TCR) functional (antigen sensitivity) and structural (monomeric pMHC-TCR off-rates) avidities o
Externí odkaz:
https://doaj.org/article/07eeb33e654749ddb84ed54edf7d260f
Autor:
John WM Martens, Reno Debets, Justine Michaux, Michal Bassani-Sternberg, Dian Kortleve, Sonja Buschow, Monique de Beijer, Dora Hammerl, Mandy Van Brakel, Rebecca Wijers, Daphne Roelofs, Madelon Badoux, Mieke A Timmermans, Anita C Liao, Erik Danen, Rachel JM Abbott
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss Suppl 1 (2023)
Externí odkaz:
https://doaj.org/article/33e6a6cb5cf54edbbedf27bd1eb6a7b0
Autor:
Bing Zhang, Michal Bassani-Sternberg
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss 10 (2023)
Identification of tumor antigens presented by the human leucocyte antigen (HLA) molecules is essential for the design of effective and safe cancer immunotherapies that rely on T cell recognition and killing of tumor cells. Mass spectrometry (MS)-base
Externí odkaz:
https://doaj.org/article/7586fbd652ac440baf8e4f894a99db4c
Autor:
Hakimeh Ebrahimi-Nik, Marmar Moussa, Ryan P. Englander, Summit Singhaviranon, Justine Michaux, HuiSong Pak, Hiroko Miyadera, William L. Corwin, Grant L. J. Keller, Adam T. Hagymasi, Tatiana V. Shcheglova, George Coukos, Brian M. Baker, Ion I. Mandoiu, Michal Bassani-Sternberg, Pramod K. Srivastava
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-11 (2021)
The immunogenicity of peptides is believed to be determined by their high-affinity binding to MHC I. Here authors show that low-affinity MHC I-peptide interactions are also able to trigger robust T cell response and anti-tumour immunity in vivo.
Externí odkaz:
https://doaj.org/article/1e4f015d0d0f4721934a300013d3a61f
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Externí odkaz:
https://doaj.org/article/8574f0256f1042d49a1b2f08d2062ee0
Autor:
Marthe Solleder, Julien Racle, Philippe Guillaume, George Coukos, Michal Bassani-Sternberg, David Gfeller
Publikováno v:
iScience, Vol 25, Iss 5, Pp 104215- (2022)
Summary: CD4+ T cell activation in infectious diseases and cancer is governed by the recognition of peptides presented on class II human leukocyte antigen (HLA-II) molecules. Therefore, HLA-II ligands represent promising targets for vaccine design an
Externí odkaz:
https://doaj.org/article/c79e975ad73e42688c1d67bbad14a835
Autor:
Janos L. Tanyi, Cheryl L.-L. Chiang, Johanna Chiffelle, Anne-Christine Thierry, Petra Baumgartener, Florian Huber, Christine Goepfert, David Tarussio, Stephanie Tissot, Drew A. Torigian, Harvey L. Nisenbaum, Brian J. Stevenson, Hajer Fritah Guiren, Ritaparna Ahmed, Anne-Laure Huguenin-Bergenat, Emese Zsiros, Michal Bassani-Sternberg, Rosemarie Mick, Daniel J. Powell, George Coukos, Alexandre Harari, Lana E. Kandalaft
Publikováno v:
npj Vaccines, Vol 6, Iss 1, Pp 1-14 (2021)
Abstract T cells are important for controlling ovarian cancer (OC). We previously demonstrated that combinatorial use of a personalized whole-tumor lysate-pulsed dendritic cell vaccine (OCDC), bevacizumab (Bev), and cyclophosphamide (Cy) elicited neo
Externí odkaz:
https://doaj.org/article/ba1d3a5199c64080b68ad63708532dda
Autor:
Chloe Chong, Markus Müller, HuiSong Pak, Dermot Harnett, Florian Huber, Delphine Grun, Marion Leleu, Aymeric Auger, Marion Arnaud, Brian J. Stevenson, Justine Michaux, Ilija Bilic, Antje Hirsekorn, Lorenzo Calviello, Laia Simó-Riudalbas, Evarist Planet, Jan Lubiński, Marta Bryśkiewicz, Maciej Wiznerowicz, Ioannis Xenarios, Lin Zhang, Didier Trono, Alexandre Harari, Uwe Ohler, George Coukos, Michal Bassani-Sternberg
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-21 (2020)
Non-canonical HLA-bound peptides from presumed non-coding regions are potential targets for cancer immunotherapy, but their discovery remains challenging. Here, the authors integrate exome sequencing, transcriptomics, ribosome profiling, and immunope
Externí odkaz:
https://doaj.org/article/f9a358af84884389af3e4820907dade6