Zobrazeno 1 - 10
of 89
pro vyhledávání: '"Michal A. Zmijewski"'
Autor:
Magdalena Gorska, Alicja Kuban-Jankowska, Michal Aleksander Zmijewski, Monika Gorzynik, Michal Szkatula, Michal Wozniak
Publikováno v:
Molecules, Vol 19, Iss 9, Pp 13267-13281 (2014)
Objective: 2-Methoxyestradiol, one of the natural 17β-estradiol derivatives, is a novel, potent anticancer agent currently being evaluated in advanced phases of clinical trials. The main goal of the study was to investigate the anticancer activity o
Externí odkaz:
https://doaj.org/article/0233a15cd287442ca5febfdfe0f05910
Autor:
Anna A. Brożyna, Radomir M. Slominski, Bogusław Nedoszytko, Michal A. Zmijewski, Andrzej T. Slominski
Publikováno v:
International journal of molecular sciences. 23(15)
Psoriasis is a systemic, chronic, immune-mediated disease that affects approximately 2–3% of the world’s population. The etiology and pathophysiology of psoriasis are still unknown, but the activation of the adaptive immune system with the main r
Autor:
Dorota Purzycka-Bohdan, Aneta Szczerkowska-Dobosz, Monika Zablotna, Justyna Wierzbicka, Anna Piotrowska, Michal A Zmijewski, Boguslaw Nedoszytko, Roman Nowicki
Publikováno v:
PLoS ONE, Vol 11, Iss 10, p e0165577 (2016)
Interleukin 16 (IL-16) has been described as a significant cytokine involved in the recruitment of CD4+ cells during inflammation; however, its potential role in psoriasis has not been defined. Our aim was to investigate the IL-16 serum levels and IL
Externí odkaz:
https://doaj.org/article/7be5d17c29d7469bb8ffe2f4cd35a3e2
Autor:
Michal A. Zmijewski, Carsten Carlberg
Publikováno v:
Experimental Dermatology. 29:876-884
The genomic actions of the vitamin D are mediated via its biologically most potent metabolite 1α,25-dihydroxyvitamin D3 (1,25(OH)2 D3 ) and the transcription factor vitamin D receptor (VDR). Activation of VDR by 1,25(OH)2 D3 leads to change in the e
Autor:
David K. Crossman, Tae Kang Kim, Jaroslaw W. Zmijewski, Michal A. Zmijewski, Shariq Qayyum, Andrzej Slominski, Radomir M. Slominski, Robert C. Tuckey, Anyamanee Chaiprasongsuk, Joanna Stefan, Uraiwan Panich, Michael F. Holick, Zorica Janjetovic, Vidya Sagar Hanumanthu, Chander Raman, Mohammad Athar, Anton M. Jetten, Yuhua Song, Yuwei Song
Publikováno v:
Cell Biochem Biophys
We have previously described new pathways of vitamin D3 activation by CYP11A1 to produce a variety of metabolites including 20(OH)D3 and 20,23(OH)(2)D3. These can be further hydroxylated by CYP27B1 to produce their C1α-hydroxyderivatives. CYP11A1 si
Autor:
Meri K. Tulic, Konrad Kleszczyński, Andrzej Slominski, F. Schedel, Anna Piotrowska, Michal A. Zmijewski, Kerstin Steinbrink, Elżbieta Pyza, Russel J. Reiter, Bernadetta Bilska, Joanna Stefan
Publikováno v:
Journal of pineal researchREFERENCES. 70(3)
Melanoma is a leading cause of cancer deaths worldwide. Although immunotherapy has revolutionized the treatment for some patients, resistance towards therapy and unwanted side effects remain a problem for numerous individuals. Broad anti-cancer activ
Autor:
Magdalena Gorska, Antonella Marino Gammazza, Michal Aleksander Zmijewski, Claudia Campanella, Francesco Cappello, Tomasz Wasiewicz, Alicja Kuban-Jankowska, Agnieszka Daca, Alicja Sielicka, Urszula Popowska, Narcyz Knap, Jakub Antoniewicz, Takashi Wakabayashi, Michal Wozniak
Publikováno v:
PLoS ONE, Vol 8, Iss 8, p e71135 (2013)
Osteosarcoma is one of the most malignant tumors of childhood and adolescence that is often resistant to standard chemo- and radio-therapy. Geldanamycin and geldanamycin analogs have been recently studied as potential anticancer agents for osteosarco
Externí odkaz:
https://doaj.org/article/f82aff0e2b464c539e76049802cccbb9
Autor:
Radomir M. Slominski, Mohammad Athar, Robert C. Tuckey, Jörg Reichrath, Tae Kang Kim, Purushotham Guroji, Andrzej Slominski, Anna A. Brożyna, Craig A. Elmets, Zorica Janjetovic, Anton M. Jetten, Rebecca S. Mason, Michal A. Zmijewski
Publikováno v:
Sunlight, Vitamin D and Skin Cancer ISBN: 9783030462260
Adv Exp Med Biol
Adv Exp Med Biol
Nonmelanoma skin cancers including basal and squamous cell carcinomas (SCC and BCC) represent a significant clinical problem due to their relatively high incidence, imposing an economic burden to healthcare systems around the world. It is accepted th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7ebc1fd574e431c69a27190bc92a9fbb
https://doi.org/10.1007/978-3-030-46227-7_13
https://doi.org/10.1007/978-3-030-46227-7_13
Publikováno v:
Endocrinology. 159:1992-2007
The skin, a self-regulating protective barrier organ, is empowered with sensory and computing capabilities to counteract the environmental stressors to maintain and restore disrupted cutaneous homeostasis. These complex functions are coordinated by a
Autor:
Allen S.W. Oak, Andrzej Slominski, Anna A. Brożyna, Michal A. Zmijewski, Craig A. Elmets, Zorica Janjetovic, Rebecca S. Mason, Robert M. Hoffman, Anton M. Jetten, Cezary Skobowiat, We Li, Wojciech Jozwicki, Tae Kang Kim, Robert C. Tuckey
Publikováno v:
The Journal of Steroid Biochemistry and Molecular Biology. 177:159-170
Melanoma represents a significant clinical problem affecting a large segment of the population with a relatively high incidence and mortality rate. Ultraviolet radiation (UVR) is an important etiological factor in malignant transformation of melanocy