Zobrazeno 1 - 10
of 343
pro vyhledávání: '"Michal, Toborek"'
Autor:
Silvia Torices, Leah Daire, Sierra Simon, Oandy Naranjo, Luisa Mendoza, Timea Teglas, Nikolai Fattakhov, Daniel Adesse, Michal Toborek
Publikováno v:
Fluids and Barriers of the CNS, Vol 20, Iss 1, Pp 1-14 (2023)
Abstract Compromised structure and function of the blood-brain barrier (BBB) is one of the pathological hallmarks of brain infection by HIV-1. BBB damage during HIV-1 infection has been associated with modified expression of tight junction (TJ) prote
Externí odkaz:
https://doaj.org/article/be2bb48628934c6abf7b98937d2365e4
Publikováno v:
iScience, Vol 26, Iss 8, Pp 107461- (2023)
Summary: For more than a century, clinicians have been aware of the devastating neurological condition called Alzheimer’s disease (AD). AD is characterized by the presence of abnormal amyloid protein plaques and tau tangles in the brain. The domina
Externí odkaz:
https://doaj.org/article/c8a371f932b84d958068fc3fb752ca25
Autor:
Nicolette Schurhoff, Michal Toborek
Publikováno v:
Molecular Brain, Vol 16, Iss 1, Pp 1-18 (2023)
Abstract Circadian disruption has become more prevalent in society due to the increase in shift work, sleep disruption, blue light exposure, and travel via different time zones. The circadian rhythm is a timed transcription-translation feedback loop
Externí odkaz:
https://doaj.org/article/132ce101248a4c8f8e54194000b86707
Autor:
Oandy Naranjo, Silvia Torices, Paul R. Clifford, Manav T. Daftari, Olivia M. Osborne, Nikolai Fattakhov, Michal Toborek
Publikováno v:
Retrovirology, Vol 19, Iss 1, Pp 1-9 (2022)
Abstract While HIV-1 is primarily an infection of CD4 + T cells, there is an emerging interest towards understanding how infection of other cell types can contribute to HIV-associated comorbidities. For HIV-1 to cross from the blood stream into tissu
Externí odkaz:
https://doaj.org/article/fe1d23929df24ad495c3baaceb18c726
Autor:
Daniel Adesse, Luis Gladulich, Liandra Alvarez-Rosa, Michele Siqueira, Anne Caroline Marcos, Marialice Heider, Caroline Soares Motta, Silvia Torices, Michal Toborek, Joice Stipursky
Publikováno v:
Fluids and Barriers of the CNS, Vol 19, Iss 1, Pp 1-19 (2022)
Abstract COVID-19, which is caused by Severe Acute Respiratory Syndrome Corona Virus 2 (SARS-CoV-2), has resulted in devastating morbidity and mortality worldwide due to lethal pneumonia and respiratory distress. In addition, the central nervous syst
Externí odkaz:
https://doaj.org/article/0e4a2efd2b0947feb67a66b31f887657
Autor:
Brianna M. Holder, Shaina E. Tolan, Kaleb K. Heinrich, Kaitlin C. Miller, Natalie Hudson, Geetika Nehra, Michelle E. Pizzo, Steffen E. Storck, William F. Elmquist, Britta Engelhardt, Irena Loryan, Michal Toborek, Bjoern Bauer, Anika M. S. Hartz, Brandon J. Kim
Publikováno v:
Fluids and Barriers of the CNS, Vol 19, Iss 1, Pp 1-11 (2022)
Abstract Background Scientific conferences are vital communication events for scientists in academia, industry, and government agencies. In the brain barriers research field, several international conferences exist that allow researchers to present d
Externí odkaz:
https://doaj.org/article/9b52a93633bb43e6822fea744263dc65
Publikováno v:
Addiction Neuroscience, Vol 4, Iss , Pp 100027- (2022)
Opioid addiction is a worldwide public health crisis stemming from the well-intentioned efforts of physicians to improve pain management in the 1990’s. The lack of knowledge behind the addictive tendencies of opioids, led to what is now known as th
Externí odkaz:
https://doaj.org/article/376c231f660e43fa92890eae485b3205
Autor:
Silvia Torices, Rosalba Cabrera, Michael Stangis, Oandy Naranjo, Nikolai Fattakhov, Timea Teglas, Daniel Adesse, Michal Toborek
Publikováno v:
Journal of Neuroinflammation, Vol 18, Iss 1, Pp 1-16 (2021)
Abstract Background Neurological complications are common in patients affected by COVID-19 due to the ability of SARS-CoV-2 to infect brains. While the mechanisms of this process are not fully understood, it has been proposed that SARS-CoV-2 can infe
Externí odkaz:
https://doaj.org/article/03e20f5f5bf546eb8ba5d8aac9a127d7
Autor:
Carolline Soares Motta, Silvia Torices, Barbara Gomes da Rosa, Anne Caroline Marcos, Liandra Alvarez-Rosa, Michele Siqueira, Thaidy Moreno-Rodriguez, Aline da Rocha Matos, Braulia Costa Caetano, Jessica Santa Cruz de Carvalho Martins, Luis Gladulich, Erick Loiola, Olivia R. M. Bagshaw, Jeffrey A. Stuart, Marilda M. Siqueira, Joice Stipursky, Michal Toborek, Daniel Adesse
Publikováno v:
Viruses, Vol 15, Iss 3, p 745 (2023)
Neurological effects of COVID-19 and long-COVID-19, as well as neuroinvasion by SARS-CoV-2, still pose several questions and are of both clinical and scientific relevance. We described the cellular and molecular effects of the human brain microvascul
Externí odkaz:
https://doaj.org/article/b2d9a075de874e7aa939bc8913b7eaee
Publikováno v:
Frontiers in Drug Delivery, Vol 2 (2022)
Drug delivery across the blood–brain barrier (BBB) has several challenges, especially toward targeting neurological diseases, due to tight and selective barrier function of the BBB. Several structural and functional components of this barrier contr
Externí odkaz:
https://doaj.org/article/d18ef7460e9d4f6bb84ad7c22d638607