Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Michal, Kriegelstein"'
Autor:
Michal Kriegelstein, Aleš Marek
Publikováno v:
Journal of Labelled Compounds and Radiopharmaceuticals. 65:244-253
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::42858a127753af1028b7af53bf00044b
https://doi.org/10.1002/jlcr.3991
https://doi.org/10.1002/jlcr.3991
Publikováno v:
Journal of Labelled Compounds and Radiopharmaceuticals. 64:500-512
Convenient and straightforward synthesis of ibrutinib labeled by carbon-13 isotope is reported. Isotopically labeled building block is introduced in the last step of reaction sequence affording sufficient isolated yield (7%) of [13 C6 ]-ibrutinib cal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a9f9ab2b23fe3f7f7306490cd7f7788a
https://doi.org/10.1002/jlcr.3944
https://doi.org/10.1002/jlcr.3944
Autor:
Michal, Kriegelstein, Aleš, Marek
Publikováno v:
Journal of labelled compoundsradiopharmaceuticalsREFERENCES. 65(9)
[
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f9b8771325667bcbb07d07cd5c4ce1a8
https://pubmed.ncbi.nlm.nih.gov/35840548
https://pubmed.ncbi.nlm.nih.gov/35840548
Publikováno v:
The Journal of Organic Chemistry. 85:12912-12921
Axially chiral trifluoromethylbenzimidazolylbenzoic acid (TBBA) was used as a chiral derivatization agent for the assignment of the absolute configuration of β-chiral primary alcohols. The structures varied from simple aliphatic alcohols to complex
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e819eea226b3a5e9a2946c3e942d00f
https://doi.org/10.1021/acs.joc.0c01510
https://doi.org/10.1021/acs.joc.0c01510
Publikováno v:
Journal of labelled compoundsradiopharmaceuticalsREFERENCES. 64(13)
Convenient and straightforward synthesis of ibrutinib labeled by carbon-13 isotope is reported. Isotopically labeled building block is introduced in the last step of reaction sequence affording sufficient isolated yield (7%) of [
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::1bd3fbf6da71a42ae468e2d37d0662c5
https://pubmed.ncbi.nlm.nih.gov/34478181
https://pubmed.ncbi.nlm.nih.gov/34478181
Publikováno v:
Journal of pharmaceutical and biomedical analysis. 206
At present, therapeutic drug monitoring is the standard in pharmacotherapy using medications with a narrow therapeutic index or showing serious adverse effects, such as in the case of ibrutinib. A technique commonly used for this purpose is liquid ch
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e7cd6796056680492da44dc5305ac6c4
https://pubmed.ncbi.nlm.nih.gov/34555634
https://pubmed.ncbi.nlm.nih.gov/34555634
Publikováno v:
Journal of Pharmaceutical and Biomedical Analysis. 206:114366
At present, therapeutic drug monitoring is the standard in pharmacotherapy using medications with a narrow therapeutic index or showing serious adverse effects, such as in the case of ibrutinib. A technique commonly used for this purpose is liquid ch
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f0d227010442d133f770f5c9f154f16b
https://doi.org/10.1016/j.jpba.2021.114366
https://doi.org/10.1016/j.jpba.2021.114366
Autor:
Sandra Benická, Michal Kriegelstein, Adam Přibylka, Antonín Lyčka, David Profous, Tereza Volná, Zdeněk Trávníček, Petr Cankař
Publikováno v:
The Journal of organic chemistry. 84(18)
Racemic 2-(2-trifluoromethyl)-1H-benzo[d]imidazol-1-yl)benzoic acid (TBBA) was synthesized in three steps from 1-fluoro-2-nitrobenzene. Target (P)- and (M)-TBBA atropisomers were stable with a racemization barrier above 30 kcal/mol. As a chiral deriv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ea701483fc7d9f0472915898d11a683c
https://pubmed.ncbi.nlm.nih.gov/31449414
https://pubmed.ncbi.nlm.nih.gov/31449414