Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Michail H Karavolos"'
Autor:
David M Bulmer, Lubna Kharraz, Andrew J Grant, Paul Dean, Fiona J E Morgan, Michail H Karavolos, Anne C Doble, Emma J McGhie, Vassilis Koronakis, Richard A Daniel, Pietro Mastroeni, C M Anjam Khan
Publikováno v:
PLoS Pathogens, Vol 8, Iss 1, p e1002500 (2012)
Although there have been great advances in our understanding of the bacterial cytoskeleton, major gaps remain in our knowledge of its importance to virulence. In this study we have explored the contribution of the bacterial cytoskeleton to the abilit
Externí odkaz:
https://doaj.org/article/0e54051753e7417a9ab0ff1ecf95a74a
Autor:
Richard Hastings, Michail H. Karavolos
Publikováno v:
Archives of Microbiology & Immunology. :112-126
The continual advancements in major technological sectors and their immediate relevance to society has led to significant changes in the way people interact in their homes and in society. Similarly, and consequently, advances in science have consider
Autor:
Michail H. Karavolos, Pietro Mastroeni, Lubna Kharraz, David M. Bulmer, Emma J. McGhie, Fiona J. E. Morgan, Paul Dean, Andrew J. Grant, Anne C. Doble, Vassilis Koronakis, Richard A. Daniel, C. M. Anjam Khan
Publikováno v:
PLoS Pathogens, Vol 8, Iss 1, p e1002500 (2012)
PLoS Pathogens
PLoS Pathogens
Although there have been great advances in our understanding of the bacterial cytoskeleton, major gaps remain in our knowledge of its importance to virulence. In this study we have explored the contribution of the bacterial cytoskeleton to the abilit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::25c9c9b343cebceab62e914a8246c9d8
Autor:
Kim M. Summers, Barry W. McColl, Sara Clohisey, Mark P. Stevens, Tom C. Freeman, Tom Michoel, Michail H. Karavolos, J Kenneth Baillie, Kathleen Grabert
Publikováno v:
Nature neuroscience
Grabert, K, Michoel, T, Karavolos, M H, Clohisey, S, Baillie, J K, Stevens, M P, Freeman, T C, Summers, K M & McColl, B W 2016, ' Microglial brain region−dependent diversity and selective regional sensitivities to aging ', Nature Neuroscience, vol. 19, no. 3, pp. 504-516 . https://doi.org/10.1038/nn.4222
Grabert, K, Michoel, T, Karavolos, M H, Clohisey, S, Baillie, J K, Stevens, M P, Freeman, T C, Summers, K M & McColl, B W 2016, ' Microglial brain region−dependent diversity and selective regional sensitivities to aging ', Nature Neuroscience, vol. 19, no. 3, pp. 504-516 . https://doi.org/10.1038/nn.4222
Microglia have critical roles in neural development, homeostasis and neuroinflammation and are increasingly implicated in age-related neurological dysfunction. Neurodegeneration often occurs in disease-specific, spatially restricted patterns, the ori
Publikováno v:
Molecular Microbiology. 87:455-465
The interactions between bacterial pathogens and their eukaryotic hosts are vital in determining the outcome of infections. Bacterial pathogens employ molecular sensors to detect and facilitate adaptation to changes in their niche. The sensing of the
Publikováno v:
Virulence
Recent studies have identified cytoskeletal elements in bacteria which play important roles in cellular morphology, cell division, DNA segregation and the establishment of cell polarity. However, our understanding of the contribution the bacterial cy
Publikováno v:
Scopus-Elsevier
The ability of bacterial pathogens to sense their immediate environment plays a significant role on their capacity to survive and cause disease. Salmonella enterica serovar typhi (S. typhi) is an exclusively human pathogen that causes typhoid fever.
Publikováno v:
Microbiology. 156:1805-1814
Salmonella enterica serovar Typhimurium (S. Typhimurium) is an important pathogen and a causative agent of gastroenteritis. During infection, S. Typhimurium assembles molecular-needle complexes termed type III secretion (T3S) systems to translocate e
Autor:
Fidel Zavala, Michail H. Karavolos, C E Hormaeche, Jeong Jin Lee, Duncan J. Maskell, David M. Bulmer, C. M. Anjam Khan, Shahid Khan, Nicola D. McKelvie, Raquel DeMarco
Publikováno v:
FEMS Immunology & Medical Microbiology. 52:237-246
Live Salmonella vaccines are limited in use by the inherent toxicity of the lipopolysaccharide. The waaN gene encodes a myristyl transferase required for the secondary acylation of lipid A in lipopolysaccharide. A waaN mutant exhibits reduced inducti
Autor:
Raquel Demarco Carlos E. Hormaeche, C. M. Anjam Khan, Wen-Tssann Liu, Jeong Jin Lee, David M. Bulmer, Abdelmounaaim Allaoui, Michail H. Karavolos
Publikováno v:
Microbial Pathogenesis. 42:2-10
Pathogenic bacteria employ a variety of mechanisms to resist a barrage of stresses they encounter during active growth in or outside the host as well as during growth stasis. An in silico screen of the Salmonella genome sequence revealed that Salmone