Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Michail A. Esterman"'
Publikováno v:
Journal of Cardiovascular Pharmacology. 45:22-29
In the present study, we report that staurosporine, a known PKC inhibitor, enhanced in vitro angiogenesis. Endothelial cells plated in a three-dimensional matrix formed cords and enclosed structures within 4-6 hours. The cells in cord structures beca
Publikováno v:
Journal of Pharmacology and Experimental Therapeutics. 307:1120-1126
The pancreatic polypeptide-fold family of peptides consists of three 36-amino acid peptides, namely neuropeptide Y (NPY), peptide YY, and pancreatic polypeptide (PP). These peptides regulate important functions, including food intake, circadian rhyth
Publikováno v:
American Journal of Physiology-Cell Physiology. 284:C1645-C1653
αENaC-EGFP (enhanced green fluorescent protein-tagged α-subunit of the epithelial Na+ channel) stably transfected clonal lines derived from the A6 parental cell line were used to study the physical mechanisms of insulin-stimulated Na+ transport. Wi
Autor:
Cynthia DeLong, Michail A. Esterman, William H. Jordan, Sandy L. White, Kelly R. Bales, Steven M. Paul, Cindy E. Fishman, David J. Cummins, Jeffery C. Hanson
Publikováno v:
Journal of Neuroscience Methods. 108:145-152
Cerebral beta-amyloidosis is a central part of the neuropathology of Alzheimer's disease (AD). Quantitation of beta-amyloid plaques in the human AD brain, and in animal models of AD, is an important study endpoint in AD research. Methodologic approac
Autor:
Rebecca L. Fouts, Xiao Di Huang, George E. Sandusky, Michail A. Esterman, Paul D. Allen, Rosemarie Maddi, Karen Mintze, Eileen McCall, Chris J. Vlahos, Nancy Bowling
Publikováno v:
Journal of Molecular and Cellular Cardiology. 33:789-798
We have previously demonstrated that protein kinase C (PKC)- alpha expression is significantly elevated in failing human left ventricle, with immunostaining showing increased PKC- alpha localization at the intercalated disks of cardiomyocytes. In the
Autor:
Michail A. Esterman
Publikováno v:
JALA: Journal of the Association for Laboratory Automation. 12:374-376
Increased sophistication in laboratory automation has increased the importance of computer technology, and has had an impact on the information technology infrastructure of organizations as a whole. Scientific imaging architecture is the subject of t
Publikováno v:
Life Sciences. 46:917-925
Anaphylactic shock was induced in actively sensitized guinea pigs by free inhalation of a high dose of ovalbumin (10 mg/ml) aerosol. Tibenelast (LY 186655), 5,6-diethoxybenzo (b)-thiophene-2-carboxylic acid, sodium salt, proved to be a potent orally
Autor:
Steven M. Paul, Michail A. Esterman, Jeffrey C. Hanson, Xin Wu, Kelly R. Bales, Seema Malkani, Milla Koistinaho, Suizhen Lin, Feng Liu, Richard E. Higgs, Deanna Koger
Publikováno v:
Nature medicine. 10(7)
We have previously shown that apolipoprotein E (Apoe) promotes the formation of amyloid in brain and that astrocyte-specific expression of APOE markedly affects the deposition of amyloid-beta peptides (Abeta) in a mouse model of Alzheimer disease. Gi
Autor:
Eileen L. Considine, Krishna Menon, Michail A. Esterman, Beverly A. Teicher, Margaret M. Faul, Enrique Alvarez, Chuan Shih
Publikováno v:
Cancer chemotherapy and pharmacology. 49(1)
Background: Protein kinase C frequently plays a central role in the intracellular signal transduction of growth factors and cytokines. Methods: The acyclic bisindolylmaleimide 317615·2HCl was identified as a potent selective inhibitor of protein kin
Autor:
Michail A. Esterman, Rebecca L. Fouts, Laura J. Bloem, George E. Sandusky, Leslie E. Lemke, Chris J. Vlahos
Publikováno v:
Journal of molecular and cellular cardiology. 33(8)
Short duration exposure to cellular stresses have been shown to activate p38 mitogen-activated protein kinase (MAPK) in cultured rat ventricular cardiomyocytes and isolated perfused hearts; however, effects of chronic stress on p38 MAPK are not well