Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Michaeline McGuinty"'
Autor:
Erin Collins, Yannick Galipeau, Corey Arnold, Anne Bhéreur, Ronald Booth, Arianne C. Buchan, Curtis Cooper, Angela M. Crawley, Pauline S. McCluskie, Michaeline McGuinty, Martin Pelchat, Lynda Rocheleau, Raphael Saginur, Chris Gravel, Steven Hawken, Marc-André Langlois, Julian Little
Publikováno v:
Frontiers in Public Health, Vol 12 (2024)
IntroductionMore than 3 years into the pandemic, there is persisting uncertainty as to the etiology, biomarkers, and risk factors of Post COVID-19 Condition (PCC). Serological research data remain a largely untapped resource. Few studies have investi
Externí odkaz:
https://doaj.org/article/03769940dcf7465a9cf8e66c1dcde6b6
Autor:
Stephanie C. Burke Schinkel, Priscila O. Barros, Tamara Berthoud, Siddappa N. Byrareddy, Michaeline McGuinty, D. William Cameron, Jonathan B. Angel
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
IntroductionAlterations in the gut immune system have been implicated in various diseases.The challenge of obtaining gut tissues from healthy individuals, commonly performed via surgical explants, has limited the number of studies describing the phen
Externí odkaz:
https://doaj.org/article/bf0e6dbe932c4eb9b5ca8f32f9976853
Autor:
Julian Little, Michaeline McGuinty, Raphael Saginur, Curtis Cooper, Marc-André Langlois, Erin Collins, Yannick Galipeau, Corey Arnold, Aliisa Heiskanen, Alexa Keeshan, Ronald Booth, C Arianne Buchan, Pauline S McCluskie, Anglea Crawley
Publikováno v:
BMJ Open, Vol 13, Iss 10 (2023)
Background Predictors of COVID-19 vaccine immunogenicity and the influence of prior severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection require elucidation.Methods Stop the Spread Ottawa is a prospective cohort of individuals at-ri
Externí odkaz:
https://doaj.org/article/1ea1481535e44878b754e0c22ea01044
Autor:
Julian Little, Michaeline McGuinty, Curtis L Cooper, Raphael Saginur, Marc-André Langlois, Erin Collins, Yannick Galipeau, Corey Arnold, Cameron Bosveld, Aliisa Heiskanen, Alexa Keeshan, Kiran Nakka, Khatereh Shir-Mohammadi, Frederic St-Denis-Bissonnette, Laura Tamblyn, Agatha Vranjkovic, Leah C Wood, Ronald Booth, C Arianne Buchan, Angela M Crawley
Publikováno v:
BMJ Open, Vol 12, Iss 9 (2022)
Purpose To investigate the robustness and longevity of SARS-CoV-2 immune responses conferred by natural infection and vaccination among priority populations such as immunocompromised individuals and people with post-acute sequelae of COVID-19 in a pr
Externí odkaz:
https://doaj.org/article/1e287f3c916a4672bc86af3d21d7ade5
Autor:
Meshach Asare-Werehene, Michaeline McGuinty, Agatha Vranjkovic, Yannick Galipeau, Juthaporn Cowan, Bill Cameron, Curtis L. Cooper, Marc-André Langlois, Angela M. Crawley, Benjamin K. Tsang
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
BackgroundPrognostic markers for COVID-19 disease outcome are currently lacking. Plasma gelsolin (pGSN) is an actin-binding protein and an innate immune marker involved in disease pathogenesis and viral infections. Here, we demonstrate the utility of
Externí odkaz:
https://doaj.org/article/41ed385a3d55480dae0151ec3e8bc4eb
Publikováno v:
Frontiers in Virology, Vol 2 (2022)
Human immunodeficiency virus (HIV) infection remains a global epidemic. While antiretroviral therapy (ART) suppresses viral replication, cessation of ART results in viral rebound necessitating lifelong treatment. This is a result of a reservoir of la
Externí odkaz:
https://doaj.org/article/720785cb753d4055b16f25b08776e9eb
Autor:
Andrea Benedetti, Cecilia T Costiniuk, Kosar Khwaja, Andrew Johnson, Barret Rush, Darrell Tan, Ranjani Somayaji, Salman Qureshi, Michaeline McGuinty, Nicole Ezer, Sara Belga, Emily G. McDonald, Zahra N. Sohani, Guillaume Butler-Laporte, Andrew Aw, Alex Carignan, Matthew P. Cheng, Bryan Coburn, Dan Gregson, Alexander Lawandi, Victor Leung, Sylvain Lother, Derek MacFadden, Leighanne Parkes, Valerie Roy, Ilan Schwartz, Miranda So, Emilie Trinh, Todd C. Lee
Publikováno v:
BMJ Open, Vol 12, Iss 7 (2022)
Introduction Pneumocystis jirovecii pneumonia (PJP) is an opportunistic infection of immunocompromised hosts with significant morbidity and mortality. The current standard of care, trimethoprim-sulfamethoxazole (TMP-SMX) at a dose of 15–20 mg/kg/da
Externí odkaz:
https://doaj.org/article/93d2ad50457b4909a009a29a7dcc8958
Autor:
Yannick Galipeau, Vinayakumar Siragam, Geneviève Laroche, Erika Marion, Matthew Greig, Michaeline McGuinty, Ronald A Booth, Yves Durocher, Miroslava Cuperlovic-Culf, Steffany A.L. Bennett, Angela M. Crawley, Patrick M. Giguère, Curtis Cooper, Marc-André Langlois
Publikováno v:
EBioMedicine, Vol 74, Iss , Pp 103700- (2021)
Background: Antibodies raised against human seasonal coronaviruses (sCoVs), which are responsible for the common cold, are known to cross-react with SARS-CoV-2 antigens. This prompts questions about their protective role against SARS-CoV-2 infections
Externí odkaz:
https://doaj.org/article/7ba81d4ec8dc43269394d064eb78b2d7
Autor:
Gary Mallach, Samantha B Kasloff, Tom Kovesi, Anand Kumar, Ryan Kulka, Jay Krishnan, Benoit Robert, Michaeline McGuinty, Sophia den Otter-Moore, Bashour Yazji, Todd Cutts
Publikováno v:
PLoS ONE, Vol 16, Iss 9, p e0258151 (2021)
BackgroundFew studies have quantified aerosol concentrations of SARS-CoV-2 in hospitals and long-term care homes, and fewer still have examined samples for viability. This information is needed to clarify transmission risks beyond close contact.Metho
Externí odkaz:
https://doaj.org/article/43496064eeca4352a7ed956c6e5d2d23
Autor:
Jonathan B Angel, Ashok Kumar, Michaeline McGuinty, Curtis L Cooper, Juthaporn Cowan, Paul A MacPherson, Sanjay Murthy, Richmond Sy, Michelle Dennehy, Nancy Tremblay, Siddappa N Byrareddy, D William Cameron
Publikováno v:
BMJ Open, Vol 10, Iss 10 (2020)
Introduction Continuous antiretroviral therapy (ART) suppresses HIV plasma viral load (pVL) to very low levels, which allows for some immune recovery. Discontinuation of ART leads to pVL rebound from reservoirs of persistence and latency, and progres
Externí odkaz:
https://doaj.org/article/36d81695384243f18a42b9d91961c5c3