Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Michaeleen Doucleff"'
Autor:
Michaeleen Doucleff
NEW YORK TIMES BESTSELLER The oldest cultures in the world have mastered the art of raising happy, well-adjusted children. What can we learn from them? “Hunt, Gather, Parent is full of smart ideas that I immediately wanted to force on my own kids.
Autor:
Michaeleen Doucleff
Las culturas más antiguas del mundo siempre han dominado el arte de criar niños felices y bien adaptados. ¿Qué podemos aprender de ellos? Una lectura obligatoria para las mamás y los papás que buscan soluciones inteligentes y creativas a los pr
Autor:
Joseph D. Batchelor, Sacha De Carlo, David E. Wemmer, Johanna Heideker, Michaeleen Doucleff, Chul-Jin Lee, Meindert H. Lamers, Jeffrey G. Pelton, Koshi Matsubara
Publikováno v:
Journal of Molecular Biology. 384:1058-1075
Genetic changes lead gradually to altered protein function, making deduction of the molecular basis for activity from a sequence difficult. Comparative studies provide insights into the functional consequences of specific changes. Here we present str
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d1fcc6932d87c25d929e834fa8f7a534
https://doi.org/10.1016/j.jmb.2008.10.024
https://doi.org/10.1016/j.jmb.2008.10.024
Publikováno v:
Journal of Molecular Biology. 369:1070-1078
The sigma subunit of bacterial RNA polymerase (RNAP) regulates gene expression by directing RNAP to specific promoters. Unlike sigma(70)-type proteins, the alternative sigma factor, sigma(54), requires interaction with an ATPase to open DNA. We prese
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::29fb60ad5daa50831fe5a5c6fb6ee34f
https://doi.org/10.1016/j.jmb.2007.04.019
https://doi.org/10.1016/j.jmb.2007.04.019
Publikováno v:
Journal of Biological Chemistry. 280:41530-41536
The ''{delta}'' subunit of prokaryotic RNA-polymerase allows gene-specific transcription initiation. Two {sigma} families have been identified, {sigma}{sup 70} and {sigma}{sup 54}, which use distinct mechanisms to initiate transcription and share no
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::911a166bcbe2241faf1849d652fe7d54
https://doi.org/10.1074/jbc.m509010200
https://doi.org/10.1074/jbc.m509010200
Autor:
B. Tracy Nixon, Michaeleen Doucleff, Jeffrey G. Pelton, Hemant P. Yennawar, Susan Krueger, Elena Kondrashkina, David E. Wemmer
Publikováno v:
Biochemistry. 44:13962-13969
Two-component signal transduction is the predominant information processing mechanism in prokaryotes and is also present in single-cell eukaryotes and higher plants. A phosphorylation-based switch is commonly used to activate as many as 40 different
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::376755904378412c700e893f1fec78e0
https://doi.org/10.1021/bi051129u
https://doi.org/10.1021/bi051129u
Autor:
Baoyu Chen, Elena Kondrashkina, B. Tracy Nixon, Michaeleen Doucleff, David E. Wemmer, Ann E. Maris
Publikováno v:
Journal of Molecular Biology. 353:242-255
Only a few transcriptional regulatory proteins have been characterized in extremely hyperthermophilic organisms, and most function as repressors. Structural features of the NtrC1 protein from the hyperthermophilic bacterium Aquifex aeolicus suggested
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c47b2fd1a6e12ac8bddb5b7438f1d4d6
https://doi.org/10.1016/j.jmb.2005.08.003
https://doi.org/10.1016/j.jmb.2005.08.003
Steering clear of quantum mechanics and product operators,'Pocket Guide to Biomolecular NMR'uses intuitive, concrete analogies to explain the theory required to understand NMR studies on the structure and dynamics of biological macromolecules. For ex
Publikováno v:
Journal of molecular biology. 425(1)
The σ subunits of bacterial RNA polymerase occur in many variant forms and confer promoter specificity to the holopolymerase. Members of the σ(54) family of σ subunits require the action of a 'transcriptional activator' protein to open the promote
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7398532c120373c0d28194fb242772d7
https://pubmed.ncbi.nlm.nih.gov/23123379
https://pubmed.ncbi.nlm.nih.gov/23123379
Publikováno v:
Journal of the American Chemical Society. 133(46)
Calmodulin (CaM) is the universal calcium sensor in eukaryotes, regulating the function of numerous proteins. Crystallography and NMR show that free CaM-4Ca(2+) exists in an extended conformation with significant interdomain separation, but clamps do
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::613c2e32ce7b608504cc8693122fffc1
https://pubmed.ncbi.nlm.nih.gov/21999431
https://pubmed.ncbi.nlm.nih.gov/21999431