Zobrazeno 1 - 10
of 55
pro vyhledávání: '"Michaela Wenzel"'
Autor:
Declan A. Gray, Biwen Wang, Margareth Sidarta, Fabián A. Cornejo, Jurian Wijnheijmer, Rupa Rani, Pamela Gamba, Kürşad Turgay, Michaela Wenzel, Henrik Strahl, Leendert W. Hamoen
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-13 (2024)
Abstract The bactericidal activity of several antibiotics partially relies on the production of reactive oxygen species (ROS), which is generally linked to enhanced respiration and requires the Fenton reaction. Bacterial persister cells, an important
Externí odkaz:
https://doaj.org/article/973560fd47384ef4942e73993a74b4e5
Autor:
Margareth Sidarta, Ana I. Lorente Martín, Anuntxi Monsalve, Gabriela Marinho Righetto, Ann-Britt Schäfer, Michaela Wenzel
Publikováno v:
Microbiology Spectrum, Vol 12, Iss 6 (2024)
ABSTRACT Membrane fluidity and thickness have emerged as crucial factors for the activity of and resistance to several antimicrobials. However, the lack of tools to study membrane fluidity and, in particular, thickness in living bacteria limits our u
Externí odkaz:
https://doaj.org/article/8aa117a493974c698bc5544d78809d95
Autor:
Ahmed M. Kamal El-sagheir, Ireny Abdelmesseh Nekhala, Mohammed K. Abd El-Gaber, Ahmed S. Aboraia, Jonatan Persson, Ann-Britt Schäfer, Michaela Wenzel, Farghaly A. Omar
Publikováno v:
ACS Omega, Vol 8, Iss 45, Pp 43271-43284 (2023)
Externí odkaz:
https://doaj.org/article/7d9e06ca033749b989cd3d87256adcd9
Autor:
Ann-Britt Schäfer, Margareth Sidarta, Ireny Abdelmesseh Nekhala, Gabriela Marinho Righetto, Aysha Arshad, Michaela Wenzel
Publikováno v:
Microbiology Spectrum, Vol 12, Iss 3 (2024)
ABSTRACTPhenotypic analysis assays such as bacterial cytological profiling (BCP) have become increasingly popular for antibiotic mode of action analysis. A plethora of dyes, protein fusions, and reporter strains are available and have been used for t
Externí odkaz:
https://doaj.org/article/7a555714268f48d789bc3c6d054aeda9
Autor:
Ahmed M. Kamal El-sagheir, Ireny Abdelmesseh Nekhala, Mohammed K. Abd El-Gaber, Ahmed S. Aboraia, Jonatan Persson, Ann-Britt Schäfer, Michaela Wenzel, Farghaly A. Omar
Publikováno v:
ACS Bio & Med Chem Au, Vol 3, Iss 6, Pp 494-506 (2023)
Externí odkaz:
https://doaj.org/article/b58ff430b5724e5db921cce6226252ef
Autor:
Michaela Wenzel, Marien P. Dekker, Biwen Wang, Maroeska J. Burggraaf, Wilbert Bitter, Jan R. T. van Weering, Leendert W. Hamoen
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-13 (2021)
Wenzel et al. developed a flat embedding method for TEM, which increases the fraction of appropriately orientated cells per image, making it easier to quantify cell morphology. They find that tetracycline-treated B. subtilis shows membrane lesions an
Externí odkaz:
https://doaj.org/article/6891a8b700bc4b0d86ca8c303d7203c1
Publikováno v:
Pharmaceuticals, Vol 15, Iss 7, p 770 (2022)
Bacteria accumulate osmolytes to prevent cell dehydration during hyperosmotic stress. A sudden change to a hypotonic environment leads to a rapid water influx, causing swelling of the protoplast. To prevent cell lysis through osmotic bursting, mechan
Externí odkaz:
https://doaj.org/article/c5ca17358e0f4d849d75a2e07ee7acf5
Autor:
Ann-Britt Schäfer, Michaela Wenzel
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 10 (2020)
Antimicrobial peptides (AMPs) are a promising alternative to classical antibiotics in the fight against multi-resistant bacteria. They are produced by organisms from all domains of life and constitute a nearly universal defense mechanism against infe
Externí odkaz:
https://doaj.org/article/32e906e0a3ee4ed5b59190217e95db82
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-18 (2017)
Abstract The conserved cell division protein SepF aligns polymers of FtsZ, the key cell division protein in bacteria, during synthesis of the (Fts)Z-ring at midcell, the first stage in cytokinesis. In addition, SepF acts as a membrane anchor for the
Externí odkaz:
https://doaj.org/article/569eec12e463423998eb20c4d829d865
Autor:
Michaela Wenzel, Marina Rautenbach, J. Arnold Vosloo, Tjalling Siersma, Christopher H. M. Aisenbrey, Ekaterina Zaitseva, Wikus E. Laubscher, Wilma van Rensburg, Jan C. Behrends, Burkhard Bechinger, Leendert W. Hamoen
Publikováno v:
mBio, Vol 9, Iss 5 (2018)
ABSTRACT Cyclic β-sheet decapeptides from the tyrocidine group and the homologous gramicidin S were the first commercially used antibiotics, yet it remains unclear exactly how they kill bacteria. We investigated their mode of action using a bacteria
Externí odkaz:
https://doaj.org/article/d9271b17950c45d6963eeb7b57386a0e