Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Michaela Veliova"'
Autor:
Essam A. Assali, Anthony E. Jones, Michaela Veliova, Rebeca Acín-Pérez, Mahmoud Taha, Nathanael Miller, Michaël Shum, Marcus F. Oliveira, Guy Las, Marc Liesa, Israel Sekler, Orian S. Shirihai
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-18 (2020)
Brown adipose tissue activation of thermogenesis is accompanied by a sequence of events commonly associated with apoptosis, however they evade cell death. Assali et al. show that NCLX prevents mitochondrial calcium overload and apoptosis. Deletion of
Externí odkaz:
https://doaj.org/article/b7d8f16459e24177b94890292b6533d2
Autor:
Rebeca Acín-Perez, Anton Petcherski, Michaela Veliova, Ilan Y. Benador, Essam A. Assali, Georgia Colleluori, Saverio Cinti, Alexandra J. Brownstein, Siyouneh Baghdasarian, Masha J. Livhits, Michael W. Yeh, Karthickeyan Chella Krishnan, Laurent Vergnes, Nathan C. Winn, Jaume Padilla, Marc Liesa, Harold S. Sacks, Orian S. Shirihai
Publikováno v:
Redox Biology, Vol 46, Iss , Pp 102087- (2021)
Beige adipocyte mitochondria contribute to thermogenesis by uncoupling and by ATP-consuming futile cycles. Since uncoupling may inhibit ATP synthesis, it is expected that expenditure through ATP synthesis is segregated to a disparate population of mi
Externí odkaz:
https://doaj.org/article/4b8e9dfe1be44446bb4a1b85629f27e1
Autor:
Jennifer Ngo, Ilan Y. Benador, Alexandra J. Brownstein, Laurent Vergnes, Michaela Veliova, Michael Shum, Rebeca Acín-Pérez, Karen Reue, Orian S. Shirihai, Marc Liesa
Publikováno v:
STAR Protocols, Vol 2, Iss 1, Pp 100243- (2021)
Summary: Mitochondria play a central role in lipid metabolism and can bind to lipid droplets. However, the role and functional specialization of the population of peridroplet mitochondria (PDMs) remain unclear, as methods to isolate functional PDMs w
Externí odkaz:
https://doaj.org/article/edfd860d7dca4c3cb26471e206507d87
Autor:
Anton Petcherski, Brett M Tingley, Andrew Martin, Sarah Adams, Alexandra J Brownstein, Ross A Steinberg, Byourak Shabane, Gustavo Garcia, Michaela Veliova, Vaithilingaraja Arumugaswami, Aaron H Colby, Orian S Shirihai, Mark W Grinstaff
SUMMARYSARS-CoV-2 can infect cells through endocytic uptake, a process which can be targeted by inhibition of lysosomal proteases. However, clinically this approach fared poorly with an oral regimen of hydroxychloroquine that was accompanied by signi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d1413cb51924367a4623110471e7a9f1
https://doi.org/10.1101/2023.05.08.539898
https://doi.org/10.1101/2023.05.08.539898
Publikováno v:
Thermogenic Fat ISBN: 9781071631669
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::85c6259b966d1371b61892f0ed90e3ad
https://doi.org/10.1007/978-1-0716-3167-6_5
https://doi.org/10.1007/978-1-0716-3167-6_5
Publikováno v:
Semin Cell Dev Biol
Proper regulation of cellular lipid storage and oxidation is indispensable for the maintenance of cellular energy homeostasis and health. Mitochondrial function has been shown to be a main determinant of functional lipid storage and oxidation, which
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6bdecb81b89fa96ca6e03ead45aa28db
https://doi.org/10.1016/j.semcdb.2020.04.013
https://doi.org/10.1016/j.semcdb.2020.04.013
Autor:
Jennifer Ngo, Ilan Benador, Michaela Veliova, Rebeca Acin-Perez, Anton Petcherski, Alexandra Brownstein, Dong Wook Choi, Janos Steffen, Sheng-Ping Wang, Cris Beninca, Lucia Fernandez, Ajit Divakaruni, Alessandro Pocai, Marc Liesa, Nika Danial, Orian Shirihai
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Bioenergetics. 1863:148612
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::468a647b18c8f51bafa1008a9ef0c725
https://doi.org/10.1016/j.bbabio.2022.148612
https://doi.org/10.1016/j.bbabio.2022.148612
Autor:
Belinda Faust, Aldons J. Lusis, Karthickeyan Chella Krishnan, Laura Nocito, Shi Su, Mayuko Segawa, Maria E. Zoghbi, Melissa Martinez, Vincent Gutierrez, Jeff Abramson, Elisabeth P. Carpenter, Roslin J. Adamson, C.A. Shintre, Michaela Veliova, Andrea L. Hevener, Dane M. Wolf, Raffi Gharakhanian, Marc Liesa, Margaret R. Young, Jennifer Ngo, Thorsten Althoff, Kiana Mahdaviani, Michael Shum, Alexandra D. Saxberg, Linsey Stiles
Publikováno v:
Sci Transl Med
Although the role of hydrophilic antioxidants in the development of hepatic insulin resistance and nonalcoholic fatty liver disease has been well studied, the role of lipophilic antioxidants remains poorly characterized. A known lipophilic hydrogen p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::66709f13f96e44d0f312e94279d73771
https://doi.org/10.1126/scitranslmed.abd1869
https://doi.org/10.1126/scitranslmed.abd1869
Autor:
Michael Shum, Marc Liesa, Orian S. Shirihai, Rebeca Acín-Pérez, Karen Reue, Michaela Veliova, Alexandra J. Brownstein, Jennifer Ngo, Ilan Y. Benador, Laurent Vergnes
Publikováno v:
STAR Protocols
STAR Protocols, Vol 2, Iss 1, Pp 100243-(2021)
STAR Protocols, Vol 2, Iss 1, Pp 100243-(2021)
Summary Mitochondria play a central role in lipid metabolism and can bind to lipid droplets. However, the role and functional specialization of the population of peridroplet mitochondria (PDMs) remain unclear, as methods to isolate functional PDMs we
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ece28235558033512ed028bb5062fb49
https://pubmed.ncbi.nlm.nih.gov/33458705
https://pubmed.ncbi.nlm.nih.gov/33458705
Autor:
Marc Liesa, Marc Prentki, Marcus F. Oliveira, Rebeca Acín-Pérez, Anthony E. Jones, Kiana Mahdaviani, Linsey Stiles, Orian S. Shirihai, Brandon R. Desousa, Ilan Y. Benador, Essam A. Assali, Alexandra J. Brownstein, Ajit S. Divakaruni, Michaela Veliova, Caroline M Ferreira, Anton Petcherski, Barbara E. Corkey
Publikováno v:
EMBO Reports
Combined fatty acid esterification and lipolysis, termed lipid cycling, is an ATP‐consuming process that contributes to energy expenditure. Therefore, interventions that stimulate energy expenditure through lipid cycling are of great interest. Here
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e3041fbbf8c965ba5accf81319386946
http://europepmc.org/articles/PMC7726774
http://europepmc.org/articles/PMC7726774