Zobrazeno 1 - 10
of 48
pro vyhledávání: '"Michaela Petter"'
Autor:
Suffian Azizan, Shamista A. Selvarajah, Jingyi Tang, Myriam D. Jeninga, Danae Schulz, Kapil Pareek, Tamara Herr, Karen P. Day, Tania F. De Koning-Ward, Michaela Petter, Michael F. Duffy
Publikováno v:
mBio, Vol 14, Iss 6 (2023)
ABSTRACTThe Plasmodium falciparum alternative histones Pf H2A.Z and Pf H2B.Z are enriched in the same nucleosomes in intergenic euchromatin but depleted from heterochromatin. They occupy most promoters but are only dynamically associated with express
Externí odkaz:
https://doaj.org/article/0360b043dc2143da902026ff0db27662
Plasmodium falciparum gametocytes display global chromatin remodelling during sexual differentiation
Autor:
Myriam D. Jeninga, Jingyi Tang, Shamista A. Selvarajah, Alexander G. Maier, Michael F. Duffy, Michaela Petter
Publikováno v:
BMC Biology, Vol 21, Iss 1, Pp 1-29 (2023)
Abstract Background The protozoan malaria parasite Plasmodium falciparum has a complex life cycle during which it needs to differentiate into multiple morphologically distinct life forms. A key process for transmission of the disease is the developme
Externí odkaz:
https://doaj.org/article/2121ad1a1f8c4a94a6433d804794cc96
Autor:
Jennifer E. Quinn, Myriam D. Jeninga, Katharina Limm, Kapil Pareek, Tina Meißgeier, Anna Bachmann, Michael F. Duffy, Michaela Petter
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 10 (2022)
Epigenetic regulation is a critical mechanism in controlling virulence, differentiation, and survival of the human malaria parasite Plasmodium (P.) falciparum. Bromodomain proteins contribute to this process by binding to acetylated lysine residues o
Externí odkaz:
https://doaj.org/article/6213dcd7d9aa4c9693b81f422ea0c278
Autor:
Arne Cordsmeier, Sven Rinkel, Myriam Jeninga, Jan Schulze-Luehrmann, Martha Ölke, Benedikt Schmid, Daniele Hasler, Gunter Meister, Georg Häcker, Michaela Petter, Paul A. Beare, Anja Lührmann
Publikováno v:
PLoS Pathogens, Vol 18, Iss 2 (2022)
Inhibition of host cell apoptosis is crucial for survival and replication of several intracellular bacterial pathogens. To interfere with apoptotic pathways, some pathogens use specialized secretion systems to inject bacterial effector proteins into
Externí odkaz:
https://doaj.org/article/94ffbda6c9e34508bd66071b94b27c11
Autor:
J. Stephan Wichers, Judith A. M. Scholz, Jan Strauss, Susanne Witt, Andrés Lill, Laura-Isabell Ehnold, Niklas Neupert, Benjamin Liffner, Renke Lühken, Michaela Petter, Stephan Lorenzen, Danny W. Wilson, Christian Löw, Catherine Lavazec, Iris Bruchhaus, Egbert Tannich, Tim W. Gilberger, Anna Bachmann
Publikováno v:
mBio, Vol 10, Iss 4 (2019)
ABSTRACT During its intraerythrocytic development, the malaria parasite Plasmodium falciparum exposes variant surface antigens (VSAs) on infected erythrocytes to establish and maintain an infection. One family of small VSAs is the polymorphic STEVOR
Externí odkaz:
https://doaj.org/article/517410248da74ba7892762b5ae7fb344
Autor:
Anna Bachmann, Ellen Bruske, Ralf Krumkamp, Louise Turner, J Stephan Wichers, Michaela Petter, Jana Held, Michael F Duffy, B Kim Lee Sim, Stephen L Hoffman, Peter G Kremsner, Bertrand Lell, Thomas Lavstsen, Matthias Frank, Benjamin Mordmüller, Egbert Tannich
Publikováno v:
PLoS Pathogens, Vol 15, Iss 7, p e1007906 (2019)
The pathogenesis of Plasmodium falciparum malaria is linked to the variant surface antigen PfEMP1, which mediates tethering of infected erythrocytes to the host endothelium and is encoded by approximately 60 var genes per parasite genome. Repeated ep
Externí odkaz:
https://doaj.org/article/f0e3b373a1e945afb416f25a061c088a
Publikováno v:
Pathogens, Vol 8, Iss 2, p 47 (2019)
Apicomplexan parasites are protozoan organisms that are characterised by complex life cycles and they include medically important species, such as the malaria parasite Plasmodium and the causative agents of toxoplasmosis (Toxoplasma gondii) and crypt
Externí odkaz:
https://doaj.org/article/6545a389ce844aaaa65c95077b5c1ce2
Autor:
Anna Bachmann, Michaela Petter, Ralf Krumkamp, Meral Esen, Jana Held, Judith A M Scholz, Tao Li, B Kim Lee Sim, Stephen L Hoffman, Peter G Kremsner, Benjamin Mordmüller, Michael F Duffy, Egbert Tannich
Publikováno v:
PLoS Pathogens, Vol 12, Iss 4, p e1005538 (2016)
Virulence of the most deadly malaria parasite Plasmodium falciparum is linked to the variant surface antigen PfEMP1, which is encoded by about 60 var genes per parasite genome. Although the expression of particular variants has been associated with d
Externí odkaz:
https://doaj.org/article/5464bcb773fb43a8aa635e2277a2665f
Autor:
Anna Bachmann, Michaela Petter, Ann-Kathrin Tilly, Laura Biller, Karin A Uliczka, Michael F Duffy, Egbert Tannich, Iris Bruchhaus
Publikováno v:
PLoS ONE, Vol 7, Iss 11, p e49540 (2012)
Avoidance of antibody-mediated immune recognition allows parasites to establish chronic infections and enhances opportunities for transmission. The human malaria parasite Plasmodium falciparum possesses a number of multi-copy gene families, including
Externí odkaz:
https://doaj.org/article/0fff85b9b1924253aaf51338c9f5cd9a
Autor:
Michaela Petter, Chin Chin Lee, Timothy J Byrne, Katja E Boysen, Jennifer Volz, Stuart A Ralph, Alan F Cowman, Graham V Brown, Michael F Duffy
Publikováno v:
PLoS Pathogens, Vol 7, Iss 2, p e1001292 (2011)
Plasmodium falciparum employs antigenic variation to evade the human immune response by switching the expression of different variant surface antigens encoded by the var gene family. Epigenetic mechanisms including histone modifications and sub-nucle
Externí odkaz:
https://doaj.org/article/a371233bd49f41d8a0bdab37ddbd6565