Upregulation of mitotic bookmarking factors during enhanced proliferation of human stromal cells in human platelet lysate

Autor: Sandra Laner-Plamberger, Michaela Oeller, Cornelia Mrazek, Arnulf Hartl, Alina Sonderegger, Eva Rohde, Dirk Strunk, Katharina Schallmoser

Publikováno v: Journal of Translational Medicine, Vol 17, Iss 1, Pp 1-13 (2019)

Abstract Background Innovative human stromal cell therapeutics require xeno-free culture conditions. Various formulations of human platelet lysate (HPL) are efficient alternatives for fetal bovine serum (FBS). However, a consistent lack of standardiz

Externí odkaz: https://doaj.org/article/90bd222f18704e199fca508cc7c9a8b9

Mitochondrial haplogroups, control region polymorphisms and malignant melanoma: a study in middle European Caucasians.

Autor: Sabine Ebner, Roland Lang, Edith E Mueller, Waltraud Eder, Michaela Oeller, Alexandra Moser, Josef Koller, Bernhard Paulweber, Johannes A Mayr, Wolfgang Sperl, Barbara Kofler

Publikováno v: PLoS ONE, Vol 6, Iss 12, p e27192 (2011)

BackgroundBecause mitochondria play an essential role in energy metabolism, generation of reactive oxygen species (ROS), and apoptosis, sequence variation in the mitochondrial genome has been postulated to be a contributing factor to the etiology of

Externí odkaz: https://doaj.org/article/a86263c3b9bf4d86a3a90b22a66ee141

Heparin and Derivatives for Advanced Cell Therapies

Autor: Michaela Oeller, Dirk Strunk, Katharina Schallmoser, Eva Rohde, Sandra Laner-Plamberger

Publikováno v: Int. J. Mol. Sci.
International Journal of Molecular Sciences, Vol 22, Iss 12041, p 12041 (2021)
International Journal of Molecular Sciences

Heparin and its derivatives are saving thousands of human lives annually, by successfully preventing and treating thromboembolic events. Although the mode of action during anticoagulation is well studied, their influence on cell behavior is not fully

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef2ed58dfd7269c83865779531a05e78
https://pubmed.ncbi.nlm.nih.gov/34769471

Human Platelet Lysate for Good Manufacturing Practice-Compliant Cell Production

Autor: Linda Krisch, Katharina Schallmoser, Eva Rohde, Dirk Strunk, Sandra Laner-Plamberger, Michaela Oeller

Publikováno v: International Journal of Molecular Sciences
International Journal of Molecular Sciences, Vol 22, Iss 5178, p 5178 (2021)

Numerous cell-based therapeutics are currently being tested in clinical trials. Human platelet lysate (HPL) is a valuable alternative to fetal bovine serum as a cell culture medium supplement for a variety of different cell types. HPL as a raw materi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e275ebd5859333c39b0946c66633aac

Collagen Receptor-Mediated Mechanochemical Signaling Contributes to Human Pro-Angiogenic Mesenchymal Stem/Progenitor Cell-Induced Neo-Vasculogenesis

Autor: Eva Rohde, Doris Peckl-Schmid, Thomas Lener, Rokhsareh Rohban, Mario Gimona, Katharina Schallmoser, Dirk Strunk, Michaela Oeller

Publikováno v: Blood. 120:5196-5196

Abstract 5196 Background and rationale Human mesenchymal stem/progenitor cells (MSPCs) are important tools for tissue repair and regenerative approaches. Co-application of autologous pairs of human MSPCs and endothelial colony forming progenitor cell

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::0b364fa0da63f4ddce207052ac5df77c
https://doi.org/10.1182/blood.v120.21.5196.5196