Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Michaela Nygårdas"'
Autor:
Ivana Colao, Rosamaria Pennisi, Assunta Venuti, Michaela Nygårdas, Outi Heikkilä, Veijo Hukkanen, Maria Teresa Sciortino
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-13 (2017)
Abstract The herpes simplex virus 1 is able to readdress different cellular pathways including cell cycle to facilitate its replication and spread. During infection, the progression of the cell cycle from G1 to S phase makes the cellular replication
Externí odkaz:
https://doaj.org/article/217a1b8760994f5d85cc707e7a290789
Autor:
Michaela Nygårdas, Henrik Paavilainen, Nadine Müther, Claus-Henning Nagel, Matias Röyttä, Beate Sodeik, Veijo Hukkanen
Publikováno v:
PLoS ONE, Vol 8, Iss 5, p e64200 (2013)
Herpes simplex virus type 1 (HSV-1) has properties that can be exploited for the development of gene therapy vectors. The neurotropism of HSV enables delivery of therapeutic genes to the nervous system. Using a bacterial artificial chromosome (BAC),
Externí odkaz:
https://doaj.org/article/f68e157352fd47a3830a6bacbd134747
Autor:
Alesia Romanovskaya, Henrik Paavilainen, Michaela Nygårdas, Dennis H Bamford, Veijo Hukkanen, Minna M Poranen
Publikováno v:
PLoS ONE, Vol 7, Iss 11, p e51019 (2012)
RNA interference (RNAi)-based sequence-specific gene silencing is applied to identify gene function and also possesses great potential for inhibiting virus replication both in animals and plants. Small interfering RNA (siRNA) molecules are the induce
Externí odkaz:
https://doaj.org/article/af84b84cbc8b49ddb5b8b9edf0c38f9a
Autor:
Michaela Nygårdas, Assunta Venuti, Maria Teresa Sciortino, Outi Heikkilä, Rosamaria Pennisi, Veijo Hukkanen, Ivana Colao
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-13 (2017)
Scientific Reports
Scientific Reports
The herpes simplex virus 1 is able to readdress different cellular pathways including cell cycle to facilitate its replication and spread. During infection, the progression of the cell cycle from G1 to S phase makes the cellular replication machinery
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e2b3eef8ae300d23ef7abce4232f9f0a
https://doaj.org/article/217a1b8760994f5d85cc707e7a290789
https://doaj.org/article/217a1b8760994f5d85cc707e7a290789
Autor:
Veijo Hukkanen, Michaela Nygårdas, Dennis H. Bamford, Jenni Lehtinen, Minna M. Poranen, Henrik Paavilainen, Alesia Romanovskaya
Publikováno v:
Antiviral Therapy. 22:631-637
Background Herpes simplex virus (HSV) is a common human pathogen. Despite current antivirals, it causes a significant medical burden. Drug resistant strains exist and they are especially prevalent in immunocompromised patients and in HSV eye infectio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb00cb1d7136925c3d36449e0c027777
http://juuli.fi/Record/0283718617
http://juuli.fi/Record/0283718617
Publikováno v:
Journal of interferoncytokine research : the official journal of the International Society for Interferon and Cytokine Research. 36(11)
Interleukin-27 (IL-27) inhibits the replication of many viruses, but the mechanism differs according to virus and cell type. In this study, we observed that IL-27 expression was upregulated in herpes simplex virus type 1 (HSV-1)-infected SJL/J mice,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::24f09197d97c9b9a94ac054cb8c34317
https://pubmed.ncbi.nlm.nih.gov/27617644
https://pubmed.ncbi.nlm.nih.gov/27617644
Autor:
Henrik, Paavilainen, Jenni, Lehtinen, Alesia, Romanovskaya, Michaela, Nygårdas, Dennis H, Bamford, Minna M, Poranen, Veijo, Hukkanen
Publikováno v:
Journal of medical virology. 88(12)
Herpes simplex virus (HSV) is a common human pathogen causing severe diseases such as encephalitis, keratitis, and neonatal herpes. There is no vaccine against HSV and the current antiviral chemotherapy fails to treat certain forms of the disease. He
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::5910c177efb3837fabec85d193df6eba
https://pubmed.ncbi.nlm.nih.gov/27191509
https://pubmed.ncbi.nlm.nih.gov/27191509
Publikováno v:
Journal of General Virology. 90:2468-2473
Coxsackievirus B3 (CBV3) is a member of the human enterovirus B species and a common human pathogen. Even though much is known about the enteroviral life cycle, no specific drugs are available to treat enterovirus infections. RNA interference (RNAi)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c9631898797143ce3d5ec1b980cac634
https://doi.org/10.1099/vir.0.011338-0
https://doi.org/10.1099/vir.0.011338-0
Autor:
Alesia Romanovskaya, Henrik Paavilainen, Minna M. Poranen, Dennis H. Bamford, Michaela Nygårdas, Veijo Hukkanen
Publikováno v:
Innate Immunity. 21(4)
Herpes simplex virus (HSV) is a human pathogen that can cause severe diseases such as encephalitis, keratitis and neonatal herpes. Control of HSV infection may be achieved by using small interfering (si)RNAs. We have designed and enzymatically produc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5768b1ccccfdc268d1195d1e4b0714b2
http://juuli.fi/Record/0006569015
http://juuli.fi/Record/0006569015
Autor:
Michaela Nygårdas, Veijo Hukkanen
Publikováno v:
Immunotherapy. 5:911-913
HSV type 1 (HSV‐1) is a common human path‐ ogen, known as the causative agent of recurrent labial herpes (cold sores). HSV is one of the most extensively studied viruses. The broad knowledge on HSV pathogenesis and viral gene functions have enabl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ab0d09b132a480b49d51c9e286e1882
https://doi.org/10.2217/imt.13.100
https://doi.org/10.2217/imt.13.100