H3K36 methylation and DNA-binding both promote Ioc4 recruitment and Isw1b remodeller function

Autor: Jian Li, Lena Bergmann, Andreia Rafael de Almeida, Kimberly M. Webb, Madelaine M. Gogol, Philipp Voigt, Yingfang Liu, Huanhuan Liang, Michaela M. Smolle

The Isw1b chromatin-remodelling complex is specifically recruited to gene bodies to help retain pre-existing histones during transcription by RNA polymerase II. Recruitment is dependent on H3K36 methylation and the Isw1b subunit Ioc4, which contains

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::e584d68dee5a22df33c77b69dc7780f5
https://doi.org/10.1101/2021.02.26.432832

ISWI catalyzes nucleosome sliding in condensed nucleosome arrays.

Autor: Vizjak P; Institute of Physiological Chemistry, Faculty of Medicine Carl Gustav Carus, Technische Universität Dresden, Fetscherstraße 74, 01307 Dresden, Germany.; Department of Molecular Biology, Biomedical Center, Faculty of Medicine, Ludwig-Maximilians-Universität München, Großhadernerstr. 9, 82152 Planegg-Martinsried, Germany., Kamp D; Gene Center, Department of Biochemistry, Ludwig-Maximilians-Universität München, Feodor-Lynen-Str 25, 81377 München, Germany., Hepp N; Department of Molecular Biology, Biomedical Center, Faculty of Medicine, Ludwig-Maximilians-Universität München, Großhadernerstr. 9, 82152 Planegg-Martinsried, Germany.; Current address: Department of Clinical Genetics, Rigshospitalet, Copenhagen University Hospital, Blegdamsvej 9, 2100 Copenhagen, Denmark., Scacchetti A; Department of Molecular Biology, Biomedical Center, Faculty of Medicine, Ludwig-Maximilians-Universität München, Großhadernerstr. 9, 82152 Planegg-Martinsried, Germany.; Current address: Epigenetics Institute & Department of Cell and Developmental Biology, University of Pennsylvania, Perelman School of Medicine, Philadelphia (PA), USA., Pisfil MG; Core Facility Bioimaging and Walter-Brendel-Centre of Experimental Medicine, Biomedical Center, Ludwig-Maximilians-Universität München, Großhaderner Straße 9, 82152, Planegg-Martinsried, Germany., Bartho J; Gene Center, Department of Biochemistry, Ludwig-Maximilians-Universität München, Feodor-Lynen-Str 25, 81377 München, Germany., Halic M; Department of Structural Biology, St. Jude Children's Research Hospital, 263 Danny Thomas Place, Memphis, TN, 38105, USA., Becker PB; Department of Molecular Biology, Biomedical Center, Faculty of Medicine, Ludwig-Maximilians-Universität München, Großhadernerstr. 9, 82152 Planegg-Martinsried, Germany., Smolle M; Department of Physiological Chemistry, Biomedical Center, Faculty of Medicine, Ludwig-Maximilians-Universität München, Großhadernerstr. 9, 82152 Planegg-Martinsried, Germany.; BioPhysics Core Facility, Biomedical Center, Faculty of Medicine, Ludwig-Maximilians-Universität München, Großhadernerstr. 9, 82152 Planegg-Martinsried, Germany., Stigler J; Gene Center, Department of Biochemistry, Ludwig-Maximilians-Universität München, Feodor-Lynen-Str 25, 81377 München, Germany., Mueller-Planitz F; Institute of Physiological Chemistry, Faculty of Medicine Carl Gustav Carus, Technische Universität Dresden, Fetscherstraße 74, 01307 Dresden, Germany.

Publikováno v: BioRxiv : the preprint server for biology [bioRxiv] 2023 Dec 04. Date of Electronic Publication: 2023 Dec 04.

Features of MOG required for recognition by patients with MOG antibody-associated disorders.

Autor: Macrini C; Institute of Clinical Neuroimmunology, Biomedical Center and University Hospitals, Ludwig-Maximilians-Universität München, 82152 Munich, Germany., Gerhards R; Institute of Clinical Neuroimmunology, Biomedical Center and University Hospitals, Ludwig-Maximilians-Universität München, 82152 Munich, Germany., Winklmeier S; Institute of Clinical Neuroimmunology, Biomedical Center and University Hospitals, Ludwig-Maximilians-Universität München, 82152 Munich, Germany., Bergmann L; Physiological Chemistry, Biomedical Center, Ludwig-Maximilians-Universität, 82152 Munich, Germany., Mader S; Institute of Clinical Neuroimmunology, Biomedical Center and University Hospitals, Ludwig-Maximilians-Universität München, 82152 Munich, Germany., Spadaro M; Institute of Clinical Neuroimmunology, Biomedical Center and University Hospitals, Ludwig-Maximilians-Universität München, 82152 Munich, Germany., Vural A; Department of Neurology, Koc University School of Medicine, 34450 Istanbul, Turkey., Smolle M; Physiological Chemistry, Biomedical Center, Ludwig-Maximilians-Universität, 82152 Munich, Germany.; BioPhysics Core Facility, Biomedical Center, Ludwig-Maximilians-Universität, 82152 Munich, Germany., Hohlfeld R; Institute of Clinical Neuroimmunology, Biomedical Center and University Hospitals, Ludwig-Maximilians-Universität München, 82152 Munich, Germany., Kümpfel T; Institute of Clinical Neuroimmunology, Biomedical Center and University Hospitals, Ludwig-Maximilians-Universität München, 82152 Munich, Germany., Lichtenthaler SF; German Center for Neurodegenerative Diseases (DZNE) Munich and Neuroproteomics, School of Medicine, Klinikum rechts der Isar, Technical University of Munich, 81675 Munich, Germany.; Munich Cluster for Systems Neurology (SyNergy), 81377 Munich, Germany., Franquelim HG; Cellular and Molecular Biophysics, Max Planck Institute of Biochemistry, 82152 Munich, Germany., Jenne D; Institute of Lung Biology and Disease (ILBD), Comprehensive Pneumology Center (CPC), 81377 Munich, Germany., Meinl E; Institute of Clinical Neuroimmunology, Biomedical Center and University Hospitals, Ludwig-Maximilians-Universität München, 82152 Munich, Germany.

Publikováno v: Brain : a journal of neurology [Brain] 2021 Sep 04; Vol. 144 (8), pp. 2375-2389.

Role of Nhp6 and Hmo1 in SWI/SNF occupancy and nucleosome landscape at gene regulatory regions.

Autor: Hepp MI; Departamento de Bioquímica y Biología Molecular, Facultad de Ciencias Biológicas, Universidad de Concepción, Barrio Universitario s/n, Concepción 4070043, Chile., Smolle M; Stowers Institute for Medical Research, 1000 E 50th Street, Kansas City, MO 64110, USA., Gidi C; Departamento de Bioquímica y Biología Molecular, Facultad de Ciencias Biológicas, Universidad de Concepción, Barrio Universitario s/n, Concepción 4070043, Chile., Amigo R; Departamento de Bioquímica y Biología Molecular, Facultad de Ciencias Biológicas, Universidad de Concepción, Barrio Universitario s/n, Concepción 4070043, Chile., Valenzuela N; Departamento de Bioquímica y Biología Molecular, Facultad de Ciencias Biológicas, Universidad de Concepción, Barrio Universitario s/n, Concepción 4070043, Chile., Arriagada A; Departamento de Bioquímica y Biología Molecular, Facultad de Ciencias Biológicas, Universidad de Concepción, Barrio Universitario s/n, Concepción 4070043, Chile., Maureira A; Departamento de Bioquímica y Biología Molecular, Facultad de Ciencias Biológicas, Universidad de Concepción, Barrio Universitario s/n, Concepción 4070043, Chile., Gogol MM; Stowers Institute for Medical Research, 1000 E 50th Street, Kansas City, MO 64110, USA., Torrejón M; Departamento de Bioquímica y Biología Molecular, Facultad de Ciencias Biológicas, Universidad de Concepción, Barrio Universitario s/n, Concepción 4070043, Chile., Workman JL; Stowers Institute for Medical Research, 1000 E 50th Street, Kansas City, MO 64110, USA., Gutiérrez JL; Departamento de Bioquímica y Biología Molecular, Facultad de Ciencias Biológicas, Universidad de Concepción, Barrio Universitario s/n, Concepción 4070043, Chile. Electronic address: lgutier@udec.cl.

Publikováno v: Biochimica et biophysica acta. Gene regulatory mechanisms [Biochim Biophys Acta Gene Regul Mech] 2017 Mar; Vol. 1860 (3), pp. 316-326. Date of Electronic Publication: 2017 Jan 09.

Swi/Snf dynamics on stress-responsive genes is governed by competitive bromodomain interactions.

Autor: Dutta A; Stowers Institute for Medical Research, Kansas City, Missouri 64110, USA;, Gogol M; Stowers Institute for Medical Research, Kansas City, Missouri 64110, USA;, Kim JH; Medical Proteomics Research Center, Korea Research Institute of Bioscience and Biotechnology, Yuseong-gu, Daejeon 305-806, Korea;, Smolle M; Stowers Institute for Medical Research, Kansas City, Missouri 64110, USA;, Venkatesh S; Stowers Institute for Medical Research, Kansas City, Missouri 64110, USA;, Gilmore J; Stowers Institute for Medical Research, Kansas City, Missouri 64110, USA;, Florens L; Stowers Institute for Medical Research, Kansas City, Missouri 64110, USA;, Washburn MP; Stowers Institute for Medical Research, Kansas City, Missouri 64110, USA; Department of Pathology and Laboratory Medicine, University of Kansas Medical Center, Kansas City, Kansas 66160, USA., Workman JL; Stowers Institute for Medical Research, Kansas City, Missouri 64110, USA;

Publikováno v: Genes & development [Genes Dev] 2014 Oct 15; Vol. 28 (20), pp. 2314-30.