Zobrazeno 1 - 10
of 82
pro vyhledávání: '"Michaela Lang"'
Autor:
Elisabeth Orgler, Maximilian Baumgartner, Stefanie Duller, Christina Kumptisch, Bela Hausmann, Doris Moser, Vineeta Khare, Michaela Lang, Thomas Köcher, Adrian Frick, Markus Muttenthaler, Athanasios Makristathis, Christine Moissl-Eichinger, Christoph Gasche
Publikováno v:
Gut Microbes, Vol 16, Iss 1 (2024)
The gut microbiota has been implicated as a driver of irritable bowel syndrome (IBS) and inflammatory bowel disease (IBD). Recently we described, mucosal biofilms, signifying alterations in microbiota composition and bile acid (BA) metabolism in IBS
Externí odkaz:
https://doaj.org/article/26bffac2a9eb40418a42c4ac2a5d1048
Autor:
Maximilian Baumgartner, Rebecca Zirnbauer, Sabine Schlager, Daniel Mertens, Nikolaus Gasche, Barbara Sladek, Craig Herbold, Olga Bochkareva, Vera Emelianenko, Harald Vogelsang, Michaela Lang, Anton Klotz, Birgit Moik, Athanasios Makristathis, David Berry, Stefanie Dabsch, Vineeta Khare, Christoph Gasche
Publikováno v:
Gut Microbes, Vol 14, Iss 1 (2022)
With increasing urbanization and industrialization, the prevalence of inflammatory bowel diseases (IBDs) has steadily been rising over the past two decades. IBD involves flares of gastrointestinal (GI) inflammation accompanied by microbiota perturbat
Externí odkaz:
https://doaj.org/article/6c622a81435d41d681ded58696d4847d
Autor:
Michaela Tanja Haindl, Muammer Üçal, Willibald Wonisch, Michaela Lang, Marta Nowakowska, Milena Z. Adzemovic, Michael Khalil, Christian Enzinger, Sonja Hochmeister
Publikováno v:
Nutrients, Vol 15, Iss 15, p 3309 (2023)
Vitamin D (VD) is the most discussed antioxidant supplement for multiple sclerosis (MS) patients and many studies suggest correlations between a low VD serum level and onset and progression of the disease. While many studies in animals as well as cli
Externí odkaz:
https://doaj.org/article/e403c965bd6e4963a628c2a94ae98748
Autor:
Rayko Evstatiev, Adam Cervenka, Tina Austerlitz, Gunther Deim, Maximilian Baumgartner, Andrea Beer, Anita Krnjic, Christina Gmainer, Michaela Lang, Adrian Frick, Helga Schachner, Vineeta Khare, Christoph Gasche
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)
Abstract Inflammatory bowel disease is a group of conditions with rising incidence caused by genetic and environmental factors including diet. The chelator ethylenediaminetetraacetate (EDTA) is widely used by the food and pharmaceutical industry amon
Externí odkaz:
https://doaj.org/article/c870e4f379f74efaa91213d474882b21
Autor:
Mario Kuttke, Dominika Hromadová, Ceren Yildirim, Julia S. Brunner, Andrea Vogel, Hannah Paar, Sophie Peters, Maria Weber, Melanie Hofmann, Martina Kerndl, Markus Kieler, Hannes Datler, Laszlo Musiejovsky, Manuel Salzmann, Michaela Lang, Klara Soukup, Angela Halfmann, Omar Sharif, Gernot Schabbauer
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Aberrant innate immune responses to the gut microbiota are causally involved in the pathogenesis of inflammatory bowel diseases (IBD). The exact triggers and main signaling pathways activating innate immune cells and how they modulate adaptive immuni
Externí odkaz:
https://doaj.org/article/8fc40d72faab43029d584838fb78452a
Autor:
Annelieke Overbeeke, Michaela Lang, Bela Hausmann, Margarete Watzka, Georgi Nikolov, Jasmin Schwarz, Gudrun Kohl, Kim De Paepe, Kevin Eislmayr, Thomas Decker, Andreas Richter, David Berry
Publikováno v:
Nutrients, Vol 14, Iss 18, p 3802 (2022)
The gut mucosal environment is key in host health; protecting against pathogens and providing a niche for beneficial bacteria, thereby facilitating a mutualistic balance between host and microbiome. Lack of dietary fiber results in erosion of the muc
Externí odkaz:
https://doaj.org/article/d7dbcd5dda7d4c9a893874d69b4d7967
Autor:
Adrian Frick, Vineeta Khare, Kristine Jimenez, Kyle Dammann, Michaela Lang, Anita Krnjic, Christina Gmainer, Maximilian Baumgartner, Ildiko Mesteri, Christoph Gasche
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 11, Iss 3, Pp 892-907.e1 (2021)
Background & Aims: p21-activated kinase-1 (PAK1) belongs to a family of serine-threonine kinases and contributes to cellular pathways such as nuclear factor-κB (NF-κB), mitogen-activated protein kinase (MAPK), phosphatidylinositol 3-kinase/protein
Externí odkaz:
https://doaj.org/article/709ac4fc74d24866bd6d4548848d2c7b
Autor:
Luigi Tortola, Roberto Nitsch, Mathieu J.M. Bertrand, Melanie Kogler, Younes Redouane, Ivona Kozieradzki, Iris Uribesalgo, Lilian M. Fennell, Mads Daugaard, Helene Klug, Gerald Wirnsberger, Reiner Wimmer, Thomas Perlot, Renu Sarao, Shuan Rao, Toshikatsu Hanada, Nozomi Takahashi, Elisabeth Kernbauer, Duygu Demiröz, Michaela Lang, Giulio Superti-Furga, Thomas Decker, Andrea Pichler, Fumiyo Ikeda, Guido Kroemer, Peter Vandenabeele, Poul H. Sorensen, Josef M. Penninger
Publikováno v:
Cell Reports, Vol 15, Iss 7, Pp 1481-1492 (2016)
Summary: The HECT domain E3 ligase HACE1 has been identified as a tumor suppressor in multiple cancers. Here, we report that HACE1 is a central gatekeeper of TNFR1-induced cell fate. Genetic inactivation of HACE1 inhibits TNF-stimulated NF-κB activa
Externí odkaz:
https://doaj.org/article/e091f3229be44c319bc3164c0e592945
Autor:
Christoph Campregher, Gerald Schmid, Franziska Ferk, Siegfried Knasmüller, Vineeta Khare, Benedikt Kortüm, Kyle Dammann, Michaela Lang, Theresa Scharl, Andreas Spittler, Andres I Roig, Jerry W Shay, Christopher Gerner, Christoph Gasche
Publikováno v:
PLoS ONE, Vol 7, Iss 11, p e50541 (2012)
Background/aimElevated microsatellite instability at selected tetranucleotide repeats (EMAST) is a genetic signature in certain cases of sporadic colorectal cancer and has been linked to MSH3-deficiency. It is currently controversial whether EMAST is
Externí odkaz:
https://doaj.org/article/37e4f1008a594872bb5cfd82f5c85f2d
Autor:
Michaela Lang, Baktybek Kojonazarov, Xia Tian, Anuar Kalymbetov, Norbert Weissmann, Friedrich Grimminger, Axel Kretschmer, Johannes-Peter Stasch, Werner Seeger, Hossein Ardeschir Ghofrani, Ralph Theo Schermuly
Publikováno v:
PLoS ONE, Vol 7, Iss 8, p e43433 (2012)
The nitric oxide (NO)-soluble guanylate cyclase (sGC)-cyclic guanosine monophosphate (cGMP) signal-transduction pathway is impaired in many cardiovascular diseases, including pulmonary arterial hypertension (PAH). Riociguat (BAY 63-2521) is a stimula
Externí odkaz:
https://doaj.org/article/1c606bf697d6478ba87d2f960a32e7b3