Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Michaela Kadlecová"'
Autor:
Silvie Hojná, Hana Malínská, Martina Hüttl, Zdeňka Vaňourková, Irena Marková, Denisa Miklánková, Jaroslav Hrdlička, František Papoušek, Jan Neckář, Petr Kujal, Michal Behuliak, Hana Rauchová, Michaela Kadlecová, David Sedmera, Kristýna Neffeová, Eva Zábrodská, Veronika Olejníčková, Josef Zicha, Ivana Vaněčková
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 174, Iss , Pp 116520- (2024)
A combination of liver and heart dysfunction worsens the prognosis of human survival. The aim of this study was to investigate whether empagliflozin (a sodium-glucose transporter-2 inhibitor) has beneficial effects not only on cardiac and renal funct
Externí odkaz:
https://doaj.org/article/ce293d8af73640869fc6eca6e079b0bb
Autor:
Silvie Hojná, Hana Rauchová, Hana Malínská, Irena Marková, Martina Hüttl, František Papoušek, Michal Behuliak, Denisa Miklánková, Zdeňka Vaňourková, Jan Neckář, Michaela Kadlecová, Petr Kujal, Josef Zicha, Ivana Vaněčková
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 144, Iss , Pp 112246- (2021)
The new antidiabetic drugs, gliflozins, inhibit sodium-glucose transporter-2 in renal proximal tubules promoting glucose and sodium excretion. This leads not only to a significant improvement of glucose control but also to the reduction of blood pres
Externí odkaz:
https://doaj.org/article/e201a9068c7440d880c7984feaa998e8
Autor:
Silvie Hojná, Zoe Kotsaridou, Zdeňka Vaňourková, Hana Rauchová, Michal Behuliak, Petr Kujal, Michaela Kadlecová, Josef Zicha, Ivana Vaněčková
Publikováno v:
Biomedicines, Vol 10, Iss 10, p 2509 (2022)
Gliflozins (sodium-glucose transporter-2 inhibitors) exhibited renoprotective effects not only in diabetic but also in non-diabetic patients with chronic kidney disease (CKD). Controversial results were reported in experimental non-diabetic models of
Externí odkaz:
https://doaj.org/article/c1aa47ac95cc44c1b6738ee49f9010da
Autor:
Ivana Vaněčková, Silvie Hojná, Zdenka Vernerová, Michaela Kadlecová, Hana Rauchová, Elzbieta Kompanowska-Jezierska, Zdeňka Vaňourková, Luděk Červenka, Josef Zicha
Publikováno v:
Frontiers in Physiology, Vol 10 (2019)
ObjectiveOur previous study in heterozygous Ren-2 transgenic rats (TGR) demonstrated that long-term treatment with endothelin receptor A (ETA) blocker atrasentan added to the renin-angiotensin system (RAS) blockade had renoprotective effects in a mod
Externí odkaz:
https://doaj.org/article/8daa08cb54f64a98ac0962f6e60ea410
Autor:
Lenka Řezáčová, Silvie Hojná, Libor Kopkan, Hana Rauchová, Michaela Kadlecová, Josef Zicha, Ivana Vaněčková
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 116, Iss , Pp 108996- (2019)
Our previous studies demonstrated that chronic systemic blockade of renin-angiotensin system (RAS) lowered blood pressure (BP) of Ren-2 transgenic rats (TGR) by the attenuation of both angiotensin II-dependent and sympathetic vasoconstriction. Since
Externí odkaz:
https://doaj.org/article/c74b0e384337412ab98fb29865854402
Publikováno v:
Physiol Res
Sex-related differences were observed not only in human but also in experimental hypertension. The aim of our study was to compare blood pressure (BP) of aged male and female heterozygous transgenic rats (TGR) harboring Ren-2 mouse gene, with their n
Autor:
Jan Neckář, Michaela Kadlecová, Martina Hüttl, S Hojná, Denisa Miklankova, Frantisek Papousek, Michal Behuliak, Josef Zicha, Hana Rauchová, Hana Malinska, Petr Kujal, Zdeňka Vaňourková, Ivana Vaněčková, Irena Markova
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 144, Iss, Pp 112246-(2021)
The new antidiabetic drugs, gliflozins, inhibit sodium-glucose transporter-2 in renal proximal tubules promoting glucose and sodium excretion. This leads not only to a significant improvement of glucose control but also to the reduction of blood pres
Autor:
Hana Rauchová, Luděk Červenka, S Hojná, Zdeňka Vaňourková, Ivana Vaněčková, Michaela Kadlecová, Elzbieta Kompanowska-Jezierska, Josef Zicha, Zdenka Vernerová
Publikováno v:
Frontiers in Physiology
Frontiers in Physiology, Vol 10 (2019)
Frontiers in Physiology, Vol 10 (2019)
Objective: Our previous study in heterozygous Ren-2 transgenic rats (TGR) demonstrated that long-term treatment with endothelin receptor A (ETA) blocker atrasentan added to the renin-angiotensin system (RAS) blockade had renoprotective effects in a m
Autor:
Ivana Vaněčková, Michaela Kadlecová, J. Zicha, Ludek Cervenka, Libor Kopkan, Zdenka Vernerová, S Hojná
Publikováno v:
Physiological Research. :S55-S67
Chronic kidney disease (CKD) is a life-threatening disease arising as a frequent complication of diabetes, obesity and hypertension. Since it is typically undetected for long periods, it often progresses to end-stage renal disease. CKD is characteriz
Autor:
Lucie Hrubá, Jiří Funda, Petra Janovska, Michal Benzce, Lenka Maletínská, Lucia Kořínková, Blanka Železná, Barbora Neprašová, Michaela Kadlecová, Jan Kopecký, Jaroslav Kuneš, Alena Karnošová, Zdenko Pirnik, Kristina Bardova, Veronika Pražienková, Jaroslav Blahos
Publikováno v:
Gene. 774:145427
G-protein-coupled receptor GPR10 is expressed in brain areas regulating energy metabolism. In this study, the effects of GPR10 gene deficiency on energy homeostasis in mice of both sexes fed either standard chow or a high-fat diet (HFD) were studied,